Results 181 to 190 of about 27,453 (249)

Integrative Analysis of Post-Translational Modifications Identifies a PTM-Enriched Regulatory Core in Human Metabolic Enzymes. [PDF]

Metabolites
Varghese S, Soman SP, Ahmed M, John L, Ramesh P, Soman S, Pai VR, Raju R.   +7 more
europepmc   +1 more source

Therapeutic Silencing of Tmprss6 Reduces Iron‐Induced Inflammation and Prolongs Survival in MDS Mice

American Journal of Hematology, Volume 101, Issue 9, Page 2105-2122, September 2026.
ABSTRACT Myelodysplastic syndromes (MDS) are a heterogeneous group of clonal hematopoietic disorders characterized by ineffective hematopoiesis, cytopenias, and an increased risk of progression to acute myeloid leukemia (AML). Despite advances in supportive and targeted therapies, disease‐modifying interventions remain limited.
Shahla Vilcassim, Nuttanan Pholngam, Rattanawan Thubthed, Tiwaporn Nualkaew, Saovaros Svasti, Pornthip Chaichompoo, Kai Kysenius, Peter J. Crouch, Sibylle Dames, Mona Eisermann, Alberto Martinez, Ute Schaeper, Jim Vadolas, George Grigoriadis   +13 more
wiley   +1 more source

Enzymatic and non-enzymatic oxidation of fibrillar collagen. [PDF]

Redox Rep
Mathias-Netto FC, Cantuária NM, Gaspar RS.   +2 more
europepmc   +1 more source

From regulatory mechanisms to cutting‐edge applications: Research progress of ultrasound, electrical, magnetic, and optical stimulation in neural modulation

Journal of Intelligent Medicine, Volume 3, Issue 3, Page 196-219, September 2026.
Abstract In recent years, the clinical treatment and symptom management of neurological disorders have faced significant challenges due to the high complexity of the nervous system's structure and function. Against this backdrop, physical stimulation techniques have emerged as a vital complementary approach to traditional pharmacological treatments and
Wanying Li, Liqun Chen
wiley   +1 more source

Global Profiling of Post-Translationally Modified Crustacean Neuropeptidome Trends Affiliated with Feeding Activity. [PDF]

J Am Soc Mass Spectrom
Fields L, Selby KG, Hayes MM, Corsetti P, Gao T, Li L.   +5 more
europepmc   +1 more source

Conformational diversity in poly‐HAMP arrays and its implications for signal transduction

Protein Science, Volume 35, Issue 9, September 2026.
Abstract Prokaryotic transmembrane receptors are built around a helical coiled‐coil backbone, with sensory, modulatory, and effector domains arranged along its length. The modulatory HAMP domain forms a parallel four‐helix coiled coil integrated into this backbone, typically connecting transmembrane segments with downstream cytosolic domains.
Murray Coles, Carolin P. Ewers, Reinhard Albrecht, Mikel Martinez‐Goikoetxea, Malgorzata Orlowska, Jörg Martin, Andrei N. Lupas, Marcus D. Hartmann, Stanislaw Dunin‐Horkawicz   +8 more
wiley   +1 more source

Landscape of Protein Post-Translational Modifications in Age-Related Neurodegenerative Disorders: Implications in Protein Aggregation, Altered Cellular Processes, and Therapeutics. [PDF]

ACS Omega
Singh AK, Kundu TK.
europepmc   +1 more source

Interplay of Ser273 Phosphorylation and K268 and K293 Acetylation in PPARγ: Implications for PPARγ Activation

Proteins: Structure, Function, and Bioinformatics, Volume 94, Issue 9, Page 1597-1609, September 2026.
ABSTRACT Post‐translational modifications (PTMs) play a critical role in regulating the transcriptional activity of PPARγ, a nuclear receptor central to glucose and lipid homeostasis. Among these, lysine acetylation at K268 and K293 and phosphorylation at S273 are particularly relevant to insulin sensitivity.
Caique Camargo Malospirito, Marieli Mariano Gonçalves Dias, Gabriel Ernesto Jara, Thayná Mendonça Avelino, Giovanna Blazutti Elias, Paulo Sergio Lopes de Oliveira, Ana Carolina Migliorini Figueira   +6 more
wiley   +1 more source

Thiol post-translational modifications modulate allosteric regulation of the OpcA-G6PDH complex through conformational gate control. [PDF]

Protein Sci
Kim H, Feng S, Bohutskyi P, Li X, Mejia-Rodriguez D, Zhang T, Qian WJ, Cheung MS.   +7 more
europepmc   +1 more source

Complete Chloroplast Genome of Indonesian Sugarcane (Saccharum ‘Bululawang’): Comparative, Structural, and Evolutionary Analysis of Photosystem I‐Encoding Genes

Journal of Sustainable Agriculture and Environment, Volume 5, Issue 3, September 2026.
ABSTRACT Sugarcane is one of the most important crops, providing the majority of global sugar production and serving as a major feedstock for bioenergy. Increasing demands for sustainable sugar production under climate and productivity constraint have intensified the need for molecular‐level characterization of elite cultivars.
Widhi Dyah Sawitri, Dwi Kusuma Wahyuni, Triono Bagus Saputro, Denianto Agung Wicaksono, Muhammad Rafi Fairuza, Tiara Putria Judith, Ganies Riza Aristya   +6 more
wiley   +1 more source