CysDBase: a comprehensive database of cysteine post-translational modifications across protein sequence, structure, microenvironment, class, cellular localization, biological pathway, and taxonomy. [PDF]
Himaja D, Bandyopadhyay D.
europepmc +1 more source
Nitrogen‐Starved Wheat: A Multi‐Omics Perspective From Epigenome Regulation to Grain Quality
This review establishes epigenetic regulation, specifically H3K27ac and H3K27me3 dynamics at nitrogen transporter, assimilation, and storage protein loci, as a principal determinant of cultivar‐specific nitrogen use efficiency in hexaploid wheat, independent of DNA sequence variation, and identifies the rhizosphere microbiome as an integral but ...
Baber Ali, Zeeshan Khan, Nijat Imin
wiley +1 more source
Microtubule dynamics and post-translational modifications in cardiovascular diseases: mechanisms and therapeutic implications. [PDF]
Cui L, Guo L, Yang L, Zhang Y, Ma C.
europepmc +1 more source
Cas9 Protein Post-translational Modifications (PTMs): A Potential Biomarker of Gene-editing
openaire +2 more sources
Cultured white adipocytes exposed to 31°C undergo cell‐autonomous metabolic adaptation characterized by enhanced mitochondrial function and widespread remodeling of the mitochondrial acetylome. Acetyl‐proteomic and metabolomic profiling identified mitochondria‐associated proteins, including SHMT2 and PCCA, whose acetylation changes were linked to ...
Hiroyuki Mori +11 more
wiley +1 more source
Expanding the Global Map of Protein Post-Translational Modifications With Immunoaffinity Enrichment and nDIA Analysis on the Orbitrap Astral Mass Spectrometer. [PDF]
Kumar M +12 more
europepmc +1 more source
PKC‐mediated phosphorylation of FOXL2 weakens DNA binding, alters subnuclear localization and protein interactions, and reshapes FOXL2‐dependent transcriptional programs in granulosa cells, supporting a reversible mechanism that modulates FOXL2 activity through phosphorylation of its DNA‐binding domain. ABSTRACT FOXL2 is a forkhead transcription factor
Ludovic Mousseron +5 more
wiley +1 more source
What Are the Practical Applications of Single-Cell Proteomics? [PDF]
Orsburn BC.
europepmc +1 more source
Lasso peptide, Microcin J25 (MccJ25), exhibits extreme stability and potent antibacterial activity against Gram‐negative bacteria due to its rigid “lariat” structure. However, this unique topology precludes researchers to achieve the total chemical synthesis. Herein, we investigated the chemical synthetic prestapling strategy toward synthesis of MccJ25
Yu‐Ting Hsiao +7 more
wiley +1 more source
Ischemia-Induced Post-Translational Modifications of GLT-1 Mediate Aberrant Trafficking and Impaired Glutamate Uptake. [PDF]
Gill SK +4 more
europepmc +1 more source

