ABSTRACT While targeted therapies have improved outcomes in lung adenocarcinoma (LUAD), many patients still lack targetable mutations. Here, we identified alpha‐L‐fucosidase 2 (FUCA2) as a crucial driver of LUAD by preventing cellular senescence. Mechanistically, through the restriction of fucosyltransferase 3 (FUT3)‐mediated α‐1,3‐fucosylation of ...
Lu Chen +18 more
wiley +1 more source
Advances in post-translational and epigenetic modification of hyperuricemia-to-gout progression: mechanisms and therapeutic targets. [PDF]
Fu W +9 more
europepmc +1 more source
Proteome-Transcriptome Discordance in Rice Under Drought Is Modulated by Post-Translational Modifications with Functional Consequences for Photosynthesis and Energy Metabolism. [PDF]
Guo Z, Yan X, Liang J.
europepmc +1 more source
Precision Profiling of the Cardiovascular Post-Translationally Modified Proteome. [PDF]
Pruktanakul T, Theofilatos K.
europepmc +1 more source
Post-Translational Modifications of NTCP: A Regulatory Nexus for Bile Acid Transport and HBV Entry. [PDF]
Yu F +7 more
europepmc +1 more source
Recombinant monoclonal antibodies for labeling tubulin post-translational modifications in <i>Caenorhabditis elegans</i>. [PDF]
Dobossy L, Wang J, Verhey KJ, Barr M.
europepmc +1 more source
Editorial: Unraveling enzyme-substrate dynamics in protein acylation and disease implications. [PDF]
Cheng S +5 more
europepmc +1 more source
Alkaline phosphatase is a vital enzyme used in separation studies and as a biomarker for liver, bone, and certain cancer conditions. Its stability and specific properties enable insights into enzyme behavior, aiding in the development of detection methods with broader applications in various scientific fields.
Eric Moore, Thanih Balbaied
exaly +2 more sources
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POSTMan (POST‐translational modification analysis), a software application for PTM discovery
PROTEOMICS, 2009AbstractPost‐translationally modified peptides present in low concentrations are often not selected for CID, resulting in no sequence information for these peptides. We have developed a software POSTMan (POST‐translational Modification analysis) allowing post‐translationally modified peptides to be targeted for fragmentation.
Magnus Ø, Arntzen +6 more
openaire +2 more sources

