Results 211 to 220 of about 5,850,387 (280)

Pan-modification proteomics: decoding tumor heterogeneity and guiding the next generation of precision oncology. [PDF]

Cancer Cell Int
Wang L, Yang Y, Yang JH.
europepmc   +1 more source

Compartmentalisation in cAMP signalling: A phase separation perspective

British Journal of Pharmacology, EarlyView.
Cells rely on precise spatiotemporal control of signalling pathways to ensure functional specificity. The compartmentalisation of cyclic AMP (cAMP) and protein kinase A (PKA) signalling enables distinct cellular responses within a crowded cytoplasmic space.
Milda Folkmanaite, Manuela Zaccolo
wiley   +1 more source

A cross-species post-translational modification profiling of histones by LC-MS/MS revealed conserved oxidative modifications in plants. [PDF]

New Phytol
Cheng SS, Sin WC, Chau YY, Lam HM.
europepmc   +1 more source

TRIM59 Drives Bladder Cancer Progression Through E3 Ligase‐Dependent K48‐Linked Degradation of PTRF

Cancer Science, EarlyView.
Schematic model of TRIM59‐driven BLCA progression through K48‐linked ubiquitination and proteasomal degradation of PTRF, leading to AKT activation and c‐Myc upregulation. ABSTRACT Tripartite motif‐containing 59 (TRIM59) is an E3 ubiquitin ligase implicated in multiple malignancies, but its role in bladder cancer (BLCA) remains incompletely understood ...
Junlin Gan, Xuesong Bai, Aijie Zhang, Fei Lin, Hang Tong, Tinghao Li, Ning Xu, Xinyuan Li, Zhou Yu, Hubin Yin   +9 more
wiley   +1 more source

Post-translational modifications of integrins: molecular mechanisms and pathological implications. [PDF]

Cell Mol Life Sci
Wu X, Zhang H, Wei X.
europepmc   +1 more source

PABPC1 in Cancer: From a Translational Housekeeper to a Stress‐Responsive Regulatory Hub

Cancer Science, EarlyView.
PABPC1 shifts from a translational housekeeper to a stress‐responsive oncogenic hub via phase separation, PTMs, and non‐coding RNA crosstalk, selectively driving oncogene translation and therapy resistance in cancer. ABSTRACT PABPC1, long recognized as a constitutive translational housekeeper, has emerged as a stress‐responsive translational ...
Cuiwei Zhang, Ye Zhu, Wenbo Long
wiley   +1 more source

Post-translational modifications in rosacea. [PDF]

Front Immunol
Zhang X, Su H, Deng W, Liu F, Liu S.
europepmc   +1 more source

Reactive oxygen species, antioxidants and the regulation of plant development

The FEBS Journal, EarlyView.
The regulation of axillary bud outgrowth by the interplay between phytohormone and redox signals. Axillary bud outgrowth is regulated by cellular energy status and the balance between phytohormones, notably abscisic acid (ABA) and gibberellic acid (GA).
Juwita R. Dewi, Christine H. Foyer, Michael J. Considine   +2 more
wiley   +1 more source

Protein Glycosylation and Its Role in Current Immunotherapeutic Strategies. [PDF]

Cancers (Basel)
Agostini M, Traldi P, Hamdan M.
europepmc   +1 more source

Mass spectrometry analysis of transthyretin (TTR) post-translational modifications (PTMs) in hereditary ATTR: a case-control Spanish experience [PDF]

Orphanet J Rare Dis, 2015
Vilà-Rico M, Contesse S, Barcena Llona J, Rojas-García R, Valle F, Planas A, Canals F, Campistol J.   +7 more
europepmc   +1 more source