Results 221 to 230 of about 14,425,416 (299)

Exploratory machine learning-based early post-treatment assessment of willingness to reuse rubber dam isolation after microscopic root canal treatment. [PDF]

J Int Med Res
Cai Y, Xiang T, Sun Q, Guan L, Zhao C.
europepmc   +1 more source

Avidin is evolutionarily conserved in fish but dispensable for development and resistance against Streptococcus agalactiae in zebrafish

FEBS Open Bio, EarlyView.
The presence of biotin‐binding avidin proteins in fish and their biological significance are poorly characterized. We cataloged fish avidins and demonstrate that they are widely present and evolutionarily conserved. We created avd knockout zebrafish and show that zebavidin is dispensable for development and that resistance of avd knockout embryos in ...
Anni K. Saralahti, Markus J. T. Ojanen, Mataleena Parikka, Otto Kauko, Mika Rämet, Vesa P. Hytönen   +5 more
wiley   +1 more source

Baseline prolonged venous transit on CT perfusion predicts the post-treatment Brush Sign after successful reperfusion in acute ischemic stroke patients. [PDF]

Front Neurol
Tsang DA, Gad M, Cho A, Lalwani K, Salim H, Lakhani D, Greene C, Koneru M, Dmytriw A, Guenego A, Hui F, Heit J, Faizy T, Albers G, Lu H, Aziz Y, Sriwastaw A, Yedavalli V.   +17 more
europepmc   +1 more source

Salmonella enterica serovar typhi limits the potency of typhoid toxin and ADP‐ribosylating toxin AB to establish a persistent infection

FEBS Open Bio, EarlyView.
The two catalytic subunits of typhoid toxin dissociate from the holotoxin in the ER of an intoxicated cell, but only CdtB exits the ER to generate immunosuppressive effects. PltA is retained in the ER and sequestered from its cytosolic target, thus allowing the anti‐inflammatory effects of CdtB to promote intestinal colonization.
Maria C. Zabala‐Rodriguez, Juliette K. Tinker, Teresa Frisan, Taj Azarian, Ken Teter   +4 more
wiley   +1 more source

Fewer breast cancers during post-treatment surveillance among patients initially staged using contrast-based imaging. [PDF]

Breast Cancer Res Treat
Yang TWW, Rose AK, Matheson J, Elder K, MacCallum C, Nickson C, Mann GB.   +6 more
europepmc   +1 more source

BCG vaccination potentiates oxidative phosphorylation in neonatal myeloid‐derived suppressor cells

FEBS Open Bio, EarlyView.
BCG vaccination enhances oxidative phosphorylation in neonatal MDSCs, impairing their immunosuppressive function. It upregulates electron transport chain genes and mitochondrial activity, increasing ATP and oxygen consumption. Pharmacological OXPHOS inhibition partially restores suppressive capacity, confirming causality.
Yingying Chen, Hui Li
wiley   +1 more source

A novel non-invasive technique for pediatric phimosis treatment: assessing efficacy and post-treatment family care - a retrospective cohort study. [PDF]

BMC Pediatr
Zhao X, Zhang L, Jin N.
europepmc   +1 more source

The C‐terminal truncated splicing variant of NK1R negatively modulates substance P‐stimulated NK1R signaling

FEBS Open Bio, EarlyView.
The neurokinin 1 receptor exists as full‐length (NK1L) and C‐terminally truncated (NK1S) splice variants. We show that NK1S heterodimerizes with NK1L, impairing Gαq coupling and Ca2+ mobilization while enhancing β‐arrestin1 recruitment. NK1S suppresses substance P‐driven gene expression and cell migration, revealing NK1S as an endogenous biased ...
Lan Phuong Nguyen, Duc Trung Nguyen, Minyoung Cho, Jihun Kim, Soyeon In, Thai Uy Nguyen, Sunghoon Hurh, Beom Jin Park, Jong‐Ik Hwang   +8 more
wiley   +1 more source

Post-treatment renal function deterioration following radiation therapy: implications for SABR in primary renal cell cancer. [PDF]

Front Oncol
Kilian MS, Fischer LA, Bensberg J, von Diest LA, Zwerenz CM, Anczykowski MZ, Bendrich S, Guhlich M, Leu M, Dröge LH, Kesztyüs TI, Uhlig A, Rieken S, El Shafie RA.   +13 more
europepmc   +1 more source

The C‐terminal domain of yeast Arginyltransferase1 is essential for its catalytic activity

FEBS Open Bio, EarlyView.
Arginyltransferase 1 (Ate1), a eukaryotic enzyme, catalyses arginylation, transferring arginine from tRNA‐Arg to the amino terminus of the target protein. Overexpression of Ate1 in yeast is lethal and is dependent on arginylation. This study elucidates how mutations in the cofactor‐binding and active site of Ate1 and truncation of its structural ...
Vikas Kumar Yadav, Shweta Shweta, Manisha Malhotra, Vikash Maurya, Akhilesh Kumar   +4 more
wiley   +1 more source