Results 41 to 50 of about 60,195 (270)

Pre-LTP requires extracellular signal-regulated kinase in the ACC

open access: yesMolecular Pain, 2016
The extracellular signal-regulated kinase is an important protein kinase for cortical plasticity. Long-term potentiation in the anterior cingulate cortex is believed to play important roles in chronic pain, fear, and anxiety.
Manabu Yamanaka   +3 more
doaj   +1 more source

The effect of combined preconditioning strategies on isokinetic strength in well trained kickboxers

open access: yesPhysical Education of Students, 2018
Background & Study Aim: The use of preconditioning strategies (PconSt) alone has a positive impact on performance. However, it is thought that there will be more impact on the performance of the combined preconditioning strategies, and this is the first ...
A. Yilmaz, V.V. Gurses, M. Gulsen
doaj   +1 more source

The effect of ischemic preconditioning on the of anaerobic performance in female student's athletes [PDF]

open access: yesفیزیولوژی ورزش و فعالیت بدنی, 2019
Purpose: Recently, effect of ischemic preconditioning (IPC) in sports as an ergogenic aid is taken into consideration. IPC may have positive effects on the athletic performance of individuals, which leads to increased capacity in exercise. So, the aim of
Akram Sharifi Moghadam   +1 more
doaj   +1 more source

Post-activation Potentiation In Propulsive Force After Specific Swimming Strength Training [PDF]

open access: yes, 2016
We investigated whether a conditioning activity (8x12.5m with 2.5min-interval using both hand paddles and parachute) induced post-activation potentiation in swimming propulsive force and whether a swimmer's force level affected a post-activation ...
AC; Barroso, R; Andries, Barbosa, O
core   +2 more sources

Αcute Effect of Two Different Post-Activation Potentiation Running Protocols on Sprint Performance of Preadolescent Boys

open access: yesProceedings, 2019
AIM: Forward and backward sprint are two types of locomotion commonly used in sports. The purpose of the present study was to examine the acute effect of two post-activation potentiation sprint protocols, including the aforementioned types of locomotion,
Dimitrios Petrakis   +2 more
doaj   +1 more source

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

open access: yesMolecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla   +9 more
wiley   +1 more source

The Acute Effects of Plyometric Exercises on Sprint Performance and Kinematics

open access: yesPhysiologia, 2023
Background: Post-activation potentiation refers to the acute and temporary enhancement of performance in explosive movements after performing a conditioning activity, such as plyometrics.
Maria Zisi   +4 more
doaj   +1 more source

Cell‐cycle‐specific lesion evolution rather than inhibition of double‐strand‐break repair underpins cisplatin radiosensitization

open access: yesMolecular Oncology, EarlyView.
We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu   +10 more
wiley   +1 more source

Acute caffeine treatment protects the developing retina from ischemia‐induced cell death

open access: yesFEBS Open Bio, EarlyView.
Caffeine reduces cell death in the developing retina under ischemia (OGD). This effect does not involve BDNF upregulation or antioxidant pathways (NRF2/VEGF). Neuroprotection occurs mainly through adenosine A2A receptor antagonism, decreasing glutamate release and excitotoxicity, highlighting caffeine's potential as an acute neuroprotective agent in ...
Amanda Alves Nascimento   +6 more
wiley   +1 more source

Impact of Asymptomatic Intracranial Hemorrhage on Outcome After Endovascular Stroke Treatment

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Endovascular treatment (EVT) achieves high rates of recanalization in acute large‐vessel occlusion (LVO) stroke, but functional recovery remains heterogeneous. While symptomatic intracranial hemorrhage (sICH) has been well studied, the prognostic impact of asymptomatic intracranial hemorrhage (aICH) after EVT is less certain ...
Shihai Yang   +22 more
wiley   +1 more source

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