Results 41 to 50 of about 460,039 (310)
The ubiquitin ligase RNF115 is required for the clearance of damaged lysosomes
FEBS Letters, EarlyView.Upon lysosomal rupture, an E3 ubiquitin ligase RNF115 translocates from the cytosol to the damaged lysosomal membrane. Moreover, RNF115 depletion impairs the clearance of damaged lysosomes, identifying it as a key regulator of lysosomal quality control.
Sae Nakanaga +3 more
wiley +1 more source
MD/MS thesis as a training tool
Indian Journal of Public Health, 2020 As part of the MD/MS thesis, a postgraduate resident plans, conducts, analyses, and reports a research study under the guidance of the faculty members of the department.
Anwita Khaitan +3 more
doaj +1 more source
Degradation mechanism of the von Willebrand factor A2 domain by nattokinase
FEBS Letters, EarlyView.Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto +3 more
wiley +1 more source
“The best part was the contact!”: Understanding postgraduate students’ experiences of wrapped MOOCs
Open Praxis, 2017 Mandated to provide support to postgraduate students, the Office of Postgraduate Studies at the University of Cape Town operates in a context characterised by limited funding and resourcing, varied student preparedness for postgraduate study, and ...
Tasneem Jaffer +2 more
doaj +1 more source
FEBS Letters, EarlyView.An unexpected alternative interaction site for ethyl viologen was identified in formate dehydrogenase 1 from Methylorubrum extorquens. Combined mutagenesis, kinetic analysis, and docking revealed that aromatic residues near an iron–sulfur cluster enable flavin mononucleotide‐independent electron transfer, offering a framework for engineering improved ...
Eleni G. Poloniataki, Yong Hwan Kim
wiley +1 more source
Naval Postgraduate Journal [PDF]
, 2001 The Joint Vision of NPSNPS Journal is published quarterly by the Naval Postgraduate ...
Naval Postgraduate School (U.S.)
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Molecular Oncology, EarlyView.Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat +8 more
wiley +1 more source
Physical Therapy Center - Naval Postgraduate School Foundation [PDF]
, 2019 Web Page Capture on this date.It’s a quiet Wednesday morning at the Naval Postgraduate School and some of America’s best and brightest soldiers are being put back together again. In a physical therapy clinic tucked within the Presidio of Monterey (Calif.)
Naval Postgraduate School Foundation
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CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3
Molecular Oncology, EarlyView.PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh +12 more
wiley +1 more source
Evaluation of the Application of Constructivist Curriculum in Higher Education: A Case Study in Shiraz University of Medical Sciences Iran [PDF]
Strides in Development of Medical Education, 2016 Background & Objective: Constructivism is an approach that has profound effects on learning and teaching approaches and thus alters education teaching learner teachers roles and learning environment The medical sciences are not exempt from this effect On
Meimanat Abedini-Baltork +3 more
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