Results 51 to 60 of about 874,288 (310)

An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane

open access: yesFEBS Letters, EarlyView.
Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa   +3 more
wiley   +1 more source

“The best part was the contact!”: Understanding postgraduate students’ experiences of wrapped MOOCs

open access: yesOpen Praxis, 2017
Mandated to provide support to postgraduate students, the Office of Postgraduate Studies at the University of Cape Town operates in a context characterised by limited funding and resourcing, varied student preparedness for postgraduate study, and ...
Tasneem Jaffer   +2 more
doaj   +1 more source

Center for Joint Services Electronic Warfare (CJSEW) (archived) [PDF]

open access: yes, 2015
Includes an image of the main page on this date and compressed file containing additional web pages.The Center for Joint Services Electronic Warfare (CJSEW) is a major focal point for both industrial and Department of Defense electronic warfare research.
Naval Postgraduate School   +1 more
core  

Fetal Brain Tumor Harboring a Unique ROCK1::BRAF Fusion

open access: yes
Pediatric Blood &Cancer, EarlyView.
Marllon Cindra Sant'Ana   +8 more
wiley   +1 more source

The ubiquitin ligase RNF115 is required for the clearance of damaged lysosomes

open access: yesFEBS Letters, EarlyView.
Upon lysosomal rupture, an E3 ubiquitin ligase RNF115 translocates from the cytosol to the damaged lysosomal membrane. Moreover, RNF115 depletion impairs the clearance of damaged lysosomes, identifying it as a key regulator of lysosomal quality control.
Sae Nakanaga   +3 more
wiley   +1 more source

Therapeutic strategies for MMAE‐resistant bladder cancer through DPP4 inhibition

open access: yesMolecular Oncology, EarlyView.
We established monomethyl auristatin E (MMAE)‐resistant bladder cancer (BC) cell lines by exposure to progressively increasing concentrations of MMAE in vitro. RNA sequencing showed DPP4 expression was increased in MMAE‐resistant BC cells. Both si‐DPP4 and the DPP4 inhibitor sitagliptin suppressed the viability of MMAE‐resistant BC cells.
Gang Li   +10 more
wiley   +1 more source

Evaluation of the Application of Constructivist Curriculum in Higher Education: A Case Study in Shiraz University of Medical Sciences Iran [PDF]

open access: yesStrides in Development of Medical Education, 2016
Background & Objective: Constructivism is an approach that has profound effects on learning and teaching approaches and thus alters education teaching learner teachers roles and learning environment The medical sciences are not exempt from this effect On
Meimanat Abedini-Baltork   +3 more
doaj  

Transition to postgraduate study: postgraduate ecological systems and identity [PDF]

open access: yesCambridge Journal of Education, 2013
This paper explores and examines the distal and proximal systems which construct social science postgraduate study in the UK and analyses the emergent identities of postgraduate students as they negotiate the multiple and interacting practices in their transition to study.
Tobbell, Jane, O'Donnell, V. L.
openaire   +1 more source

Use of electronic resources by postgraduate students in University of Cape Coast [PDF]

open access: yes, 2019
The study investigates the use of electronic resources by postgraduate students in University of Cape Coast (UCC). It specifically targets first year postgraduate students of UCC. Awareness, usage, training, and access were explored.
Agyapong, Emmanuel Manu, Mr   +2 more
core   +1 more source

Recurrent cancer‐associated ERBB4 mutations are transforming and confer resistance to targeted therapies

open access: yesMolecular Oncology, EarlyView.
We show that the majority of the 18 analyzed recurrent cancer‐associated ERBB4 mutations are transforming. The most potent mutations are activating, co‐operate with other ERBB receptors, and are sensitive to pan‐ERBB inhibitors. Activating ERBB4 mutations also promote therapy resistance in EGFR‐mutant lung cancer.
Veera K. Ojala   +15 more
wiley   +1 more source

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