An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane
Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa +3 more
wiley +1 more source
“The best part was the contact!”: Understanding postgraduate students’ experiences of wrapped MOOCs
Mandated to provide support to postgraduate students, the Office of Postgraduate Studies at the University of Cape Town operates in a context characterised by limited funding and resourcing, varied student preparedness for postgraduate study, and ...
Tasneem Jaffer +2 more
doaj +1 more source
Center for Joint Services Electronic Warfare (CJSEW) (archived) [PDF]
Includes an image of the main page on this date and compressed file containing additional web pages.The Center for Joint Services Electronic Warfare (CJSEW) is a major focal point for both industrial and Department of Defense electronic warfare research.
Naval Postgraduate School +1 more
core
Fetal Brain Tumor Harboring a Unique ROCK1::BRAF Fusion
Pediatric Blood &Cancer, EarlyView.
Marllon Cindra Sant'Ana +8 more
wiley +1 more source
The ubiquitin ligase RNF115 is required for the clearance of damaged lysosomes
Upon lysosomal rupture, an E3 ubiquitin ligase RNF115 translocates from the cytosol to the damaged lysosomal membrane. Moreover, RNF115 depletion impairs the clearance of damaged lysosomes, identifying it as a key regulator of lysosomal quality control.
Sae Nakanaga +3 more
wiley +1 more source
Therapeutic strategies for MMAE‐resistant bladder cancer through DPP4 inhibition
We established monomethyl auristatin E (MMAE)‐resistant bladder cancer (BC) cell lines by exposure to progressively increasing concentrations of MMAE in vitro. RNA sequencing showed DPP4 expression was increased in MMAE‐resistant BC cells. Both si‐DPP4 and the DPP4 inhibitor sitagliptin suppressed the viability of MMAE‐resistant BC cells.
Gang Li +10 more
wiley +1 more source
Evaluation of the Application of Constructivist Curriculum in Higher Education: A Case Study in Shiraz University of Medical Sciences Iran [PDF]
Background & Objective: Constructivism is an approach that has profound effects on learning and teaching approaches and thus alters education teaching learner teachers roles and learning environment The medical sciences are not exempt from this effect On
Meimanat Abedini-Baltork +3 more
doaj
Transition to postgraduate study: postgraduate ecological systems and identity [PDF]
This paper explores and examines the distal and proximal systems which construct social science postgraduate study in the UK and analyses the emergent identities of postgraduate students as they negotiate the multiple and interacting practices in their transition to study.
Tobbell, Jane, O'Donnell, V. L.
openaire +1 more source
Use of electronic resources by postgraduate students in University of Cape Coast [PDF]
The study investigates the use of electronic resources by postgraduate students in University of Cape Coast (UCC). It specifically targets first year postgraduate students of UCC. Awareness, usage, training, and access were explored.
Agyapong, Emmanuel Manu, Mr +2 more
core +1 more source
We show that the majority of the 18 analyzed recurrent cancer‐associated ERBB4 mutations are transforming. The most potent mutations are activating, co‐operate with other ERBB receptors, and are sensitive to pan‐ERBB inhibitors. Activating ERBB4 mutations also promote therapy resistance in EGFR‐mutant lung cancer.
Veera K. Ojala +15 more
wiley +1 more source

