Results 101 to 110 of about 77,986 (211)

The postsynaptic density in excitatory synapses is composed of clustered, heterogeneous nanoblocks. [PDF]

J Cell Biol
Sun R, Allen JP, Mao Z, Wilson L, Haider M, Alten B, Zhou Z, Wang X, Zhou Q.   +8 more
europepmc   +1 more source

New opportunities for bioscaffold‐enabled spinal cord injury repair

BMEMat, EarlyView.
Schematic illustration of bioscaffolds for spinal cord injury repair. We summarize the effects of bioscaffold properties on SCI repair, highlight different types of bioscaffolds, various fabrication strategies, and in vivo transformations for the clinical development of SCI‐repairing bioscaffolds.
Xiaoqing Qi, Yicheng Fu, Zhaoliang Su, Li Li, Subrata Chakrabarti, Peng Li, Yilun Wu, Fang Liu, Teng Gao, Zhifeng Dong, Lei Liu, Pei Cao   +11 more
wiley   +1 more source

Molecular and topographic mapping of antipsychotic effects: a meta-analysis of postsynaptic density proteins in animal models with translational implications. [PDF]

Mol Psychiatry
De Simone G, De Prisco M, Oliva V, Vellucci L, Ciccarelli M, Mazza B, Fico G, Fornaro M, Iasevoli F, Vieta E, de Bartolomeis A.   +10 more
europepmc   +1 more source

Bioinspired Crossmodal Tactile Sensory Nerve for High‐Accurate Object Recognition

ENERGY &ENVIRONMENTAL MATERIALS, EarlyView.
An artificial crossmodal sensory neuron system (ACSNS) that combines a complementary memristor with high‐sensitivity pressure–temperature bimodal sensors, which integrate tactile perception, information storage, and neuromorphic computing. With the aid of machine learning, this ACSNS presents an improved accuracy of 96.67% in recognizing temperatures ...
Delu Chen, Yuetong Han, Xiaodong Wang, Wanli Cheng, Jianjie He, Xing Li, Yoshifumi Oshima, Chongxin Shan, Shaobo Cheng   +8 more
wiley   +1 more source

Tubulin and GTP Are Crucial Elements for Postsynaptic Density Construction and Aggregation. [PDF]

J Neurochem
Suzuki T, Fujii T, Kametani K, Li W, Tabuchi K.   +4 more
europepmc   +1 more source

Long‐lasting remodeling of astrocytes in an Scna1+/− mouse model of Dravet syndrome

Epilepsia, EarlyView.
Abstract Objective Dravet syndrome (DS) is a prototypical developmental and epileptic encephalopathy caused by mutations in the SCN1A gene, leading to loss of function of the voltage‐gated sodium channel Naᵥ1.1. The latter causes early onset drug‐resistant seizures and enduring cognitive and behavioral deficits.
Athénaïs Genin, Alicia Janvier, Tristan Moujellil‐Legagneur, Marine Blaquière, Alexis Chaussy, Romane Privé, Fabrice Duprat, Massimo Mantegazza, Etienne Audinat, Nicola Marchi, Noémie Cresto   +10 more
wiley   +1 more source

Omega-3 fatty acid normalizes postsynaptic density related miRNAs and proteins in hippocampus and prevents DEHP-induced impairment of learning and memory in mice. [PDF]

PLoS One
Ding M, Ma H, Du H, Yang Y, Yu M, Zhang C.   +5 more
europepmc   +1 more source

Compound heterozygous SLC12A5 variants expand the molecular and functional spectrum of KCC2‐developmental and epileptic encephalopathy

Epilepsia, EarlyView.
Overview of the multimodal experimental approach integrating clinical, genetic, in silico, and in vitro investigations. Clinical: Representative EEG recording setup and ictal traces from affected patients. Genetic: Pedigrees for Families A and B highlighting the inheritance of the four identified SLC12A5 variants (A1, A2, B1, B2).
Mira Hamze, Robyn Whitney, Dorothée Ville, Nathalie Villeneuve, Anna‐Maria Hartmann, Lisa Becker, Jens Hausmann, Jinwei Zhang, Cathy Brier, Lucie I. Pisella, Perrine Friedel, Audrey Labalme, Eudeline Alix, Nicolas Chatron, Damien Sanlaville, Sylvie Gory‐Fauré, Eric Denarier, Christophe Porcher, Gaetan Lesca, Igor Medina   +19 more
wiley   +1 more source

Preclinical Replication Study of the Postsynaptic Density Protein-95 Inhibitor Nerinetide. [PDF]

J Clin Neurol
Kim H, Choi S, Kim DE.
europepmc   +1 more source

Pyruvate dehydrogenase autoantibodies in autoantibody‐negative patients with seizures are associated with reduced pyruvate dehydrogenase activity

Epilepsia, EarlyView.
Abstract Objective We investigated the presence and potential functional relevance of antimitochondrial autoantibodies in patients suspicious for autoimmune encephalitis (AIE) associated with psychiatric symptoms and/or seizures, who were negative for known antineuronal autoantibodies.
Annika Breuer, Chiara A. Hummel, Tobias Baumgartner, Juliane L. Berns, Afaf Milad Said, Isabel Bünger, Susanne Schoch, Gábor Zsurka, Harald Prüss, Wolfram S. Kunz, Rainer Surges, Albert J. Becker, Julika Pitsch   +12 more
wiley   +1 more source