Results 151 to 160 of about 136,994 (263)

Tracking Genetic Parkinson's Disease with Molecular Imaging: A Systematic Review

open access: yesMovement Disorders Clinical Practice, EarlyView.
Abstract Background Parkinson's disease (PD) is a worldwide, complex neurodegenerative disorder influenced by both genetic and environmental factors. Around 15–20% of PD cases are linked to genetic mutations, providing insights into the disease's pathogenesis.
Chiara Meneghini   +5 more
wiley   +1 more source

Low-Grade Papillary Urothelial Carcinoma of the Bladder Presenting as Persistent Genital Arousal Disorder/Genito-Pelvic Dysesthesia: A Case Report. [PDF]

open access: yesCase Rep Urol
Ponce S   +8 more
europepmc   +1 more source

Spatiotemporal Progression Patterns of Striatal Dopamine Depletion and Cerebral Hypoperfusion in Parkinson's Disease

open access: yesMovement Disorders, EarlyView.
Abstract Background The identification of Parkinson's disease (PD) subtypes is crucial for predicting the disease course and designing personalized therapeutic strategies. Objectives The aim of the study was to characterize the heterogeneity of the spatiotemporal evolutionary patterns of striatal dopamine depletion and cerebral hypoperfusion in PD ...
Yeeun Sun   +9 more
wiley   +1 more source

Bi4Ti2.85Zr0.15O12/Nb: SrTiO3‐Based Artificial Optic Neuron for Synaptic Plasticity Simulation and Light‐Controlled Neuromorphic Computing

open access: yesMaterials Genome Engineering Advances, EarlyView.
An optoelectronic synapse based on Zr‐doped Bi4Ti3O12 exhibits learning/forgetting mimicry and achieves 94.2% accuracy on MNIST, demonstrating a novel pathway for high‐performance neuromorphic computing. ABSTRACT This study enhanced the optoelectronic properties of BIT (Bi4Ti3O12) through Zr doping at the B site, constructing an Au/Bi4Ti2.85Zr0.15O12 ...
Dongping Yang   +5 more
wiley   +1 more source

SNAP47 Silencing Impairs the Morphology and Neurotransmission of Hippocampal GABAergic Neurons. [PDF]

open access: yesMol Neurobiol
He Z   +6 more
europepmc   +1 more source

AGRN‐, LRP4‐, MUSK‐Related CMS: Clinical, Neurophysiological, Morphological, Genetic and Pathological Mechanisms

open access: yesMuscle &Nerve, EarlyView.
ABSTRACT Congenital myasthenic syndromes (CMS) are inherited disorders caused by mutations in genes encoding proteins essential for neuromuscular junction (NMJ) function. Pathogenic variants have been identified in more than 35 genes, underscoring the complexity of synaptic biology and the wide range of mechanisms that can compromise neuromuscular ...
Rocio‐Nur Villar‐Quiles   +5 more
wiley   +1 more source

Synaptic Facilitation Enhances the Reliability and Precision of High-Frequency Neurotransmission. [PDF]

open access: yesJ Neurosci
Bernal-Correa AM   +3 more
europepmc   +1 more source

Presynaptic Congenital Myasthenic Syndromes

open access: yesMuscle &Nerve, EarlyView.
ABSTRACT Presynaptic congenital myasthenic syndromes (CMS) encompass a large number of rare neurologic disorders caused by impaired release of acetylcholine (ACh) from motor nerve terminals. There are two main groups of presynaptic CMS: one in which the amount of ACh in synaptic vesicles (SV) is diminished and another in which the mechanism of synaptic
Ricardo A. Maselli
wiley   +1 more source

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