Results 231 to 240 of about 10,517,225 (330)

Propofol enhances the field excitatory postsynaptic potentials in CA1 hippocampal slices of young and aged mice

open access: gold, 2014
Yiqing Yin   +4 more
openalex   +1 more source

Differential Effects of Levodopa and Stimulation on Post‐Surgery Freezing of Gait in Subthalamic Nucleus Deep Brain Stimulation Parkinson's Disease Patients: A Clinical and Kinematic Analysis

open access: yesMovement Disorders Clinical Practice, EarlyView.
Abstract Background The long‐term efficacy of high‐frequency subthalamic nucleus deep brain stimulation (STN‐DBS) on freezing of gait (FOG) remains unclear. We aimed to study the mechanism and optimal therapeutic approach to long‐term post‐surgery FOG.
Raquel Barbosa   +13 more
wiley   +1 more source

Investigation of the Determinants of Disease Severity in Patients with Idiopathic Normal Pressure Hydrocephalus

open access: yesMovement Disorders Clinical Practice, EarlyView.
Background The determinants of the severity of idiopathic normal pressure hydrocephalus (iNPH) have not been examined previously. Objective To reveal the clinical determinants of the clinical severity of iNPH in detail. To provide some clinical remarks and contributions to the understanding of the pathophysiology.
Halil Onder   +3 more
wiley   +1 more source

Exploring Autophagy Inducing Molecules: Targeting Diverse Pathways in Alzheimer's Disease Management

open access: yesMedicinal Research Reviews, EarlyView.
ABSTRACT Neurodegenerative disorders, including Alzheimer's disease (AD), impose a significant burden on society due to their progressive nature and the associated healthcare costs. Autophagy, a vital cellular degradation process, has emerged as a promising therapeutic target in these disorders.
Baljinder Singh   +4 more
wiley   +1 more source

Topiramate Enhances GABAergic Tone to Orexigenic Neuropeptide Y/Agouti‐Related Peptide (NPY/AgRP) Neurons

open access: yesObesity, EarlyView.
ABSTRACT Objective Topiramate is a medication used off‐label, or in combination with phentermine, for the management of obesity. However, its mechanism of action remains elusive. As many obesity medications target the brain, we aimed to determine if topiramate influences the activity of hypothalamic melanocortin neurons known to regulate energy balance.
Moein Minbashi Moeini   +4 more
wiley   +1 more source

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