Results 271 to 280 of about 10,435,031 (361)
Impacts of perinatal nicotine exposure on nicotinic acetylcholine receptor expression and glutamatergic synaptic transmission in the mouse auditory brainstem. [PDF]
Wollet M+5 more
europepmc +1 more source
Proteomic Insight Into Alzheimer's Disease Pathogenesis Pathways
ABSTRACT Alzheimer's disease (AD) is a leading cause of dementia, but the pathogenesis mechanism is still elusive. Advances in proteomics have uncovered key molecular mechanisms underlying AD, revealing a complex network of dysregulated pathways, including amyloid metabolism, tau pathology, apolipoprotein E (APOE), protein degradation ...
Taekyung Ryu+3 more
wiley +1 more source
For the advancement of neuromorphic computing and bio‐integrated electronics, a dual‐stacked ITO/IGZO/ZrO2/Ti resistive random access memory (RRAM) device with oxygen vacancy engineering is demonstrated for reliable synaptic and nociceptive behavior. Gradual potentiation and depression, along with biologically inspired spike‐timing‐dependent plasticity
Seo‐Young Jo+4 more
wiley +1 more source
Sleep Deprivation in Rats Causes Dissociation of the Synaptic NMDA Receptor/D1 Dopamine Receptor Heterocomplex. [PDF]
Kiknadze N+8 more
europepmc +1 more source
Update on Gene Therapy in the Treatment of Hereditary Hearing Loss
Gene therapy is a promising therapeutic approach for genetic disorders, including three major gene therapy strategies: gene replacement, gene suppression, and gene editing. After transmitting genes to the inner ear through appropriate pathways, repair the cochlea in order to achieve the goal of treating hereditary hearing loss.
Weiwei He+7 more
wiley +1 more source
Conductive Materials and Electrical Stimulation for Auditory Restoration
Applications of electroconductive biomaterials and electrical stimulation in cochlear tissue engineering.(1) Enable auditory neural repair through conductive materials and electrical stimulation, enhancing neuron survival and synaptic plasticity.(2) Integrate optogenetic‐electrical systems and cochlear organoid platforms for frequency‐specific ...
Menghui Liao+8 more
wiley +1 more source
Illuminating LGI1 Seizure Mechanisms Using Novel Optical Techniques. [PDF]
Stafstrom CE.
europepmc +1 more source
MXene‐Based Flexible Memory and Neuromorphic Devices
The unique two‐dimensional structure, excellent electrical conductivity, and diverse surface groups of MXenes have garnered significant attention. Coupled with their exceptional flexibility, MXene‐based devices hold immense potential for flexible memory and neuromorphic systems. This review comprehensively discusses the fundamentals of flexible devices,
Yan Li+13 more
wiley +1 more source
Molecular organization of central cholinergic synapses. [PDF]
Rosenthal JS+10 more
europepmc +1 more source