Results 1 to 10 of about 119,060 (284)

Posttranslational Modification in Bone Homeostasis and Osteoporosis [PDF]

MedComm
Bone is responsible for providing mechanical protection, attachment sites for muscles, hematopoiesis micssroenvironment, and maintaining balance between calcium and phosphorate.
Yuzhe Lin, Shide Jiang, Yuming Yao, Hengzhen Li, Hongfu Jin, Guang Yang, Bingzhou Ji, Yusheng Li   +7 more
doaj   +2 more sources

Protein ISGylation: a posttranslational modification with implications for malignant neoplasms [PDF]

Exploration of Targeted Anti-tumor Therapy, 2023
Interferon (IFN)-stimulated gene 15 (ISG15) is a member of the ubiquitin-like (UBL) protein family that can modify specific proteins via a catalytic process called ISGylation.
Angeles C. Tecalco-Cruz, Jesús Zepeda-Cervantes   +1 more
doaj   +2 more sources

Balancing acts: The posttranslational modification tightrope of flavivirus replication. [PDF]

PLoS Pathogens
Posttranslational modifications (PTMs) such as phosphorylation, ubiquitination, SUMOylation, and ISGylation are involved in various cellular pathways, including innate immunity and disease processes.
RuthMabel Boytz, Maudry Laurent-Rolle
doaj   +2 more sources

Posttranslational modification of Elongation Factor P from Staphylococcus aureus [PDF]

FEBS Open Bio, 2020
Antibiotic‐resistant Staphylococcus aureus is becoming a major burden on health care systems in many countries, necessitating the identification of new targets for antibiotic development.
Alexander Golubev, Luc Negroni, Filipp Krasnovid, Shamil Validov, Gulnara Yusupova, Marat Yusupov, Konstantin Usachev   +6 more
doaj   +2 more sources

Angelica gigas extract inhibits acetylation of eNOS via IRE1α sulfonation/RIDD-SIRT1-mediated posttranslational modification in vascular dysfunction. [PDF]

Aging (Albany NY), 2023
Lee GH, Lee HY, Lim YJ, Kim JH, Jung SJ, Jung ES, Chae SW, Lee J, Lim J, Rashid MMU, Min KH, Chae HJ.   +11 more
europepmc   +3 more sources

A novel posttranslational modification of histone, H3 S-sulfhydration, is down-regulated in asthenozoospermic sperm. [PDF]

J Assist Reprod Genet, 2021
Qi Q, Pan H, Jiang N, Zhang M, Sun S, Wan X, Zhang F, Zhang L, Diao H, Wang J, Li R.   +10 more
europepmc   +3 more sources

Posttranslational modification and beyond: interplay between histone deacetylase 6 and heat-shock protein 90. [PDF]

Mol Med, 2021
Liu P, Xiao J, Wang Y, Song X, Huang L, Ren Z, Kitazato K, Wang Y.   +7 more
europepmc   +3 more sources

Proteome-Wide Analysis of Lysine 2-Hydroxyisobutyrylation in Candida albicans

mSystems, 2021
Candida albicans is the most common human fungal pathogen, causing diseases ranging from mucosal to systemic infections for both immunocompetent and immunocompromised individuals.
Hailin Zheng, Nana Song, Xiaowei Zhou, Huan Mei, Dongmei Li, Xiaofang Li, Weida Liu   +6 more
doaj   +1 more source

AMPylation profiling during neuronal differentiation reveals extensive variation on lysosomal proteins

iScience, 2021
Summary: Protein AMPylation is a posttranslational modification with an emerging role in neurodevelopment. In metazoans two highly conserved protein AMP-transferases together with a diverse group of AMPylated proteins have been identified using chemical ...
Tobias Becker, Cedric Cappel, Francesco Di Matteo, Giovanna Sonsalla, Ewelina Kaminska, Fabio Spada, Silvia Cappello, Markus Damme, Pavel Kielkowski   +8 more
doaj   +1 more source

Histone lysine methacrylation is a dynamic post-translational modification regulated by HAT1 and SIRT2

Cell Discovery, 2021
Histone lysine crotonylation is a posttranslational modification with demonstrated functions in transcriptional regulation. Here we report the discovery of a new type of histone posttranslational modification, lysine methacrylation (Kmea), corresponding ...
Kyle Delaney, Minjia Tan, Zhesi Zhu, Jinjun Gao, Lunzhi Dai, Sunjoo Kim, Jun Ding, Maomao He, Levon Halabelian, Lu Yang, Prabakaran Nagarajan, Mark Robert Parthun, Sangkyu Lee, Saadi Khochbin, Yujun George Zheng, Yingming Zhao   +15 more
doaj   +1 more source