Results 1 to 10 of about 117,832 (333)

Posttranslational Modification in Bone Homeostasis and Osteoporosis [PDF]

MedComm
Bone is responsible for providing mechanical protection, attachment sites for muscles, hematopoiesis micssroenvironment, and maintaining balance between calcium and phosphorate.
Yuzhe Lin, Shide Jiang, Yuming Yao, Hengzhen Li, Hongfu Jin, Guang Yang, Bingzhou Ji, Yusheng Li   +7 more
doaj   +2 more sources

Protein ISGylation: a posttranslational modification with implications for malignant neoplasms [PDF]

Exploration of Targeted Anti-tumor Therapy, 2023
Interferon (IFN)-stimulated gene 15 (ISG15) is a member of the ubiquitin-like (UBL) protein family that can modify specific proteins via a catalytic process called ISGylation.
Angeles C. Tecalco-Cruz, Jesús Zepeda-Cervantes   +1 more
doaj   +2 more sources

Balancing acts: The posttranslational modification tightrope of flavivirus replication. [PDF]

PLoS Pathogens
Posttranslational modifications (PTMs) such as phosphorylation, ubiquitination, SUMOylation, and ISGylation are involved in various cellular pathways, including innate immunity and disease processes.
RuthMabel Boytz, Maudry Laurent-Rolle
doaj   +2 more sources

Posttranslational modification of Elongation Factor P from Staphylococcus aureus [PDF]

FEBS Open Bio, 2020
Antibiotic‐resistant Staphylococcus aureus is becoming a major burden on health care systems in many countries, necessitating the identification of new targets for antibiotic development.
Alexander Golubev, Luc Negroni, Filipp Krasnovid, Shamil Validov, Gulnara Yusupova, Marat Yusupov, Konstantin Usachev   +6 more
doaj   +2 more sources

Archaeal Protein Biogenesis: Posttranslational Modification and Degradation [PDF]

, 2010
Jerry Eichler, Julie A. Maupin‐Furlow, Jörg Soppa   +2 more
openalex   +3 more sources

Proteome-Wide Analysis of Lysine 2-Hydroxyisobutyrylation in Candida albicans

mSystems, 2021
Candida albicans is the most common human fungal pathogen, causing diseases ranging from mucosal to systemic infections for both immunocompetent and immunocompromised individuals.
Hailin Zheng, Nana Song, Xiaowei Zhou, Huan Mei, Dongmei Li, Xiaofang Li, Weida Liu   +6 more
doaj   +1 more source

AMPylation profiling during neuronal differentiation reveals extensive variation on lysosomal proteins

iScience, 2021
Summary: Protein AMPylation is a posttranslational modification with an emerging role in neurodevelopment. In metazoans two highly conserved protein AMP-transferases together with a diverse group of AMPylated proteins have been identified using chemical ...
Tobias Becker, Cedric Cappel, Francesco Di Matteo, Giovanna Sonsalla, Ewelina Kaminska, Fabio Spada, Silvia Cappello, Markus Damme, Pavel Kielkowski   +8 more
doaj   +1 more source

Comparative genomics of Burkholderia multivorans, a ubiquitous pathogen with a highly conserved genomic structure [PDF]

, 2017
The natural environment serves as a reservoir of opportunistic pathogens. A well-established method for studying the epidemiology of such opportunists is multilocus sequence typing, which in many cases has defined strains predisposed to causing infection.
Peeters, Charlotte, Cooper, Vaughn S, Hatcher, Philip J, Verheyde, Bart, Carlier, Aurélien, Vandamme, Peter   +5 more
core   +13 more sources

Histone lysine methacrylation is a dynamic post-translational modification regulated by HAT1 and SIRT2

Cell Discovery, 2021
Histone lysine crotonylation is a posttranslational modification with demonstrated functions in transcriptional regulation. Here we report the discovery of a new type of histone posttranslational modification, lysine methacrylation (Kmea), corresponding ...
Kyle Delaney, Minjia Tan, Zhesi Zhu, Jinjun Gao, Lunzhi Dai, Sunjoo Kim, Jun Ding, Maomao He, Levon Halabelian, Lu Yang, Prabakaran Nagarajan, Mark Robert Parthun, Sangkyu Lee, Saadi Khochbin, Yujun George Zheng, Yingming Zhao   +15 more
doaj   +1 more source

Effects of the Acetyltransferase p300 on Tumour Regulation from the Novel Perspective of Posttranslational Protein Modification

Biomolecules, 2023
p300 acts as a transcription coactivator and an acetyltransferase that plays an important role in tumourigenesis and progression. In previous studies, it has been confirmed that p300 is an important regulator in regulating the evolution of malignant ...
Qingmei Zeng, Kun Wang, Yongxiang Zhao, Qingzhi Ma, Zhinan Chen, Wan Huang   +5 more
doaj   +1 more source