Results 211 to 220 of about 71,707 (290)

Posttranslational Modification of Constitutive Nitric Oxide Synthase in the Penis [PDF]

, 2009
Biljana Musicki, Ashley E. Ross, Hunter C. Champion, Arthur L. Burnett, Trinity J. Bivalacqua   +4 more
openalex   +1 more source

Mining Alzheimer's Interactomes, Macromolecular Complexes and Pathways for Drug Discovery

PROTEOMICS, EarlyView.
ABSTRACT Alzheimer's disease (AD) is a progressive neurodegenerative disorder that leads to dementia. Many cases are diagnosed annually and there is no currently available cure. Understanding the underlying disease biology of AD through the study of molecular networks, particularly by mapping clinical variants to tissue‐specific interactomes and ...
Kalpana Panneerselvam, Krishna Kumar Tiwari, Luana Licata, Simona Panni, Sylvie Ricard‐Blum, Sucharitha Balu, Susie Huget, Juan Jose Medina Reyes, Eliot Ragueneau, Livia Perfetto, Birgit Meldal, Sandra Orchard, Henning Hermjakob   +12 more
wiley   +1 more source

Posttranslational modification and beyond: interplay between histone deacetylase 6 and heat-shock protein 90. [PDF]

Mol Med, 2021
Liu P, Xiao J, Wang Y, Song X, Huang L, Ren Z, Kitazato K, Wang Y.   +7 more
europepmc   +1 more source

Proteoform Identification Using Multiplexed Top‐Down Mass Spectra

PROTEOMICS, EarlyView.
ABSTRACT Top‐down mass spectrometry (TDMS) is the method of choice for analyzing intact proteoforms, as well as their posttranslational modifications and sequence variations. In top‐down tandem mass spectrometry (TD‐MS/MS) experiments, multiple proteoforms are often co‐fragmented, resulting in multiplexed TD‐MS/MS spectra.
Zhige Wang, Xingzhao Xiong, Xiaowen Liu
wiley   +1 more source

Alzheimer's disease associated AKAP9 I2558M mutation alters posttranslational modification and interactome of tau and cellular functions in CRISPR-edited human neuronal cells. [PDF]

Aging Cell, 2022
You Y, Hersh SW, Aslebagh R, Shaffer SA, Ikezu S, Mez J, Lunetta KL, Logue MW, Farrer LA, Ikezu T.   +9 more
europepmc   +1 more source

Targeting Posttranslational Modifications – Perspectives for Biocatalyst Engineering

, 2005
Beate Pscheidt, Roland Weís, Anton Glieder   +2 more
openalex   +2 more sources

Chemoproteomic Profiling of Reactive Cysteines in Response to Oxidative Stress Induced by 6‐Hydroxydopamine

PROTEOMICS, EarlyView.
ABSTRACT Although oxidative stress is a well‐established driver of neurodegeneration, it remains poorly understood as to how the global cysteine (Cys) proteome is remodeled under oxidative stress conditions. Proteins with aberrantly modified cysteines in response to oxidative stress can induce and exacerbate neurodegeneration, contributing to disorders
Rayan Murtada, Chiho Kim, Xu‐dong Wang, Youkai Yang, Yonghao Yu   +4 more
wiley   +1 more source

Archaeal Protein Biogenesis: Posttranslational Modification and Degradation [PDF]

, 2010
Jerry Eichler, Julie A. Maupin‐Furlow, Jörg Soppa   +2 more
openalex   +1 more source

The Crystal Structure of Human Transport and Golgi Organization 2 Homolog (TANGO2) Protein Reveals an αββα‐Fold Arrangement

Proteins: Structure, Function, and Bioinformatics, EarlyView.
ABSTRACT Transport and Golgi Organization 2 Homolog (TANGO2) protein deficiency disorder (TDD) is a rare autosomal recessive disorder characterized by multi‐systemic abnormalities and significant phenotypic variability including neurodevelopmental delay, seizures, intermittent ataxia, hypothyroidism, rhabdomyolysis, life‐threatening metabolic ...
Anne Cooper, Alyssa Powers, Kevin P. Battaile, Al‐Walid Mohsen, David K. Johnson, Scott Lovell, Lina Ghaloul‐Gonzalez   +6 more
wiley   +1 more source

msqrob2PTM: Differential Abundance and Differential Usage Analysis of MS-Based Proteomics Data at the Posttranslational Modification and Peptidoform Level. [PDF]

Mol Cell Proteomics
Demeulemeester N, Gébelin M, Caldi Gomes L, Lingor P, Carapito C, Martens L, Clement L.   +6 more
europepmc   +1 more source