Results 81 to 90 of about 15,278 (270)

Physiological and Pharmacological Manipulations with Light Flashes [PDF]

open access: yes, 1982
In the experiments described here, a physiological measurement is made while photochemical procedures are employed to alter (a) the concentration of a ligand near membranes or proteins or (b) the structure of the ligand-receptor complexes.
Lester, Henry A., Nerbonne, Jeanne M.
core   +1 more source

Optoelectrical Devices for Neural Interfacing: Engineering Integration, Stability, and Multimodal Sensing

open access: yesAdvanced Healthcare Materials, EarlyView.
Implantable optoelectrical devices are an effective resource for the modulation and monitoring of neural activity with high spatiotemporal resolution. This review discusses current challenges faced by these devices and outlines future perspectives for the development of next‐generation neural interfaces targeting chronic, multisite, and multimodal ...
Stella Aslanoglou   +4 more
wiley   +1 more source

Potassium-Competitive Acid Blockers: New Opportunities of Antisecretory Therapy in Gastroesophageal Reflux Disease

open access: yesРоссийский журнал гастроэнтерологии, гепатологии, колопроктологии
Aim: to present modern data on the efficacy and safety of using potassium-competitive acid blockers (P-CAB) using tegoprazan as an example in patients with gastroesophageal reflux disease.Key points.
A. S. Trukhmanov, D. E. Rumyantseva
doaj   +1 more source

The Beta-1-Receptor Blocker Nebivolol Elicits Dilation of Cerebral Arteries by Reducing Smooth Muscle [Ca2+]i [PDF]

open access: yes, 2018
K
Cséplő, Péter   +5 more
core   +1 more source

Bacteria‐Responsive Nanostructured Drug Delivery Systems for Targeted Antimicrobial Therapy

open access: yesAdvanced Materials, EarlyView.
Bacteria‐responsive nanocarriers are designed to release antimicrobials only in the presence of infection‐specific cues. This selective activation ensures drug release precisely at the site of infection, avoiding premature or indiscriminate release, and enhancing efficacy.
Guillermo Landa   +3 more
wiley   +1 more source

Current status of drug screening and disease modelling in human pluripotent stem cells [PDF]

open access: yes, 2012
The emphasis in human pluripotent stem cell (hPSC) technologies has shifted from cell therapy to in vitro disease modelling and drug screening. This review examines why this shift has occurred, and how current technological limitations might be overcome ...
Crutchley, James   +6 more
core   +2 more sources

POM‐Based Water Splitting Catalyst Under Acid Conditions Driven by Its Assembly on Carbon Nanotubes

open access: yesAdvanced Materials, EarlyView.
A newly‐engineered POM‐based electrocatalyst incorporating non‐innocent counter cations exhibits fast kinetics for either the OER or HER under strongly acidic conditions (1 m H2SO4), depending on whether it is assembled on carbon nanotubes (1@CNT) or physically mixed with them (1/CNT). In water‐splitting tests using a two‐electrode setup, these systems
Eugenia P. Quirós‐Díez   +8 more
wiley   +1 more source

Potassium-Competitive Acid Blockers for the Treatment of Gastroesophageal Reflux Disease

open access: yesForegut: The Journal of the American Foregut Society, 2023
Current treatments for gastroesophageal reflux disease (GERD) and other acid-related disorders either block stimulation of the parietal cell (H2-receptor antagonists) or inhibit gastric H+/K+-ATPase (proton pump inhibitors; PPIs). PPIs are usually very effective in healing esophageal erosions and improving heartburn in patients with GERD. However, the
Jiten P. Kothadia, Colin W. Howden
openaire   +1 more source

Current research status and trends of potassium-competitive acid blockers in the treatment of acid-related diseases: a bibliometric analysis

open access: yesFrontiers in Pharmacology
ObjectiveTo explore the current research status and trends of potassium-competitive acid blockers (P-CABs) in the treatment of acid related diseases (ARDs) using bibliometric analysis.Materials and methodsWe collected publications related to P-CAB in the
Baoqiang Zhu   +7 more
doaj   +1 more source

Seven‐day vonoprazan‐based triple therapy as first‐line Helicobacter pylori treatment in comparison with extended sequential therapy

open access: yesJGH Open, 2023
Background and Aim Vonoprazan as a new acid blocker has more potency and longer lasting acid suppression than proton pump inhibitors. Whether the efficacy of vonoprazan‐based triple therapy is comparable with or even better than that of currently ...
Yu‐Tse Chiu   +7 more
doaj   +1 more source

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