Structures of the T cell potassium channel Kv1.3 with immunoglobulin modulators
Nature Communications, 2022 The Kv1.3 potassium channel is expressed abundantly on activated T cells and mediates the cellular immune responses. Here, the authors report structures of the Kv1.3 potassium channel with and without immunoglobulin modulators, shedding light on the ...
Purushotham Selvakumar +10 more
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Pharmacological Actions of Potassium Channel Openers on Voltage-Gated Potassium Channels [PDF]
PharmaceuticalsBackground/Objectives: Potassium (K+) channels are essential transmembrane proteins that regulate ion flow, playing a critical role in regulating action potentials and neuronal transmission.
Michael T. McCoy +3 more
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Phα1β interaction with the Kv11.1 potassium channel in HEK293 cells transfected with the human ERG channel [PDF]
Journal of Venomous Animals and Toxins including Tropical DiseasesBackground: This study examines the impact of Phα1β, a spider peptide derived from the venom of Phoneutria nigriventer, on the Kv11.1 potassium channel in HEK293 cells transfected with the human ERG potassium channel.
João B. Calixto +5 more
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Potassium channel‐mediated NO‐induced vasodilation during maturation: Dominance of Kv7 channels [PDF]
FASEB BioAdvancesMaturation represents a process characterized by adaptive changes, particularly in the circulatory system. However, it is not known whether, in neonates, potassium channels contribute to NO‐induced vasorelaxation at all and, if so, which potassium ...
Anastasia A. Shvetsova +4 more
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Potassium channel‐related epilepsy: Pathogenesis and clinical features [PDF]
Epilepsia OpenVariants in potassium channel‐related genes are one of the most important mechanisms underlying abnormal neuronal excitation and disturbances in the cellular resting membrane potential.
Tong Zhao, Le Wang, Fang Chen
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BK potassium channel modulation by leucine-rich repeat-containing proteins [PDF]
Proceedings of the National Academy of Sciences of the United States of America, 2012 Jiusheng Yan, Richard W. Aldrich
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Stereoselective block of the hERG potassium channel by the Class Ia antiarrhythmic drug disopyramide. [PDF]
Cell Mol Life SciZhang Y +5 more
europepmc +3 more sources
When Is a Potassium Channel Not a Potassium Channel?
Function, 2022 Ever since they were first observed in Purkinje fibers of the heart, funny channels have had close connections to potassium channels. Indeed, funny channels were initially thought to produce a potassium current in the heart called IK2.
E. Accili
semanticscholar +1 more source
Membranes, 2023 In the inner mitochondrial membrane, several potassium channels that play a role in cell life and death have been identified. One of these channels is the ATP-regulated potassium channel (mitoKATP).
Milena Krajewska +3 more
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Unique features of two potassium channels, OsKAT2 and OsKAT3, expressed in rice guard cells. [PDF]
PLoS ONE, 2013 Potassium is the most abundant cation and a myriad of transporters regulate K(+) homeostasis in plant. Potassium plays a role as a major osmolyte to regulate stomatal movements that control water utility of land plants.
Hyunsik Hwang +10 more
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