Results 1 to 10 of about 441,765 (225)

Effect of channel block on the spiking activity of excitable membranes in a stochastic Hodgkin-Huxley model [PDF]

PHYSICAL BIOLOGY 1, pp. 61-66 (2004), 2006
The influence of intrinsic channel noise on the spontaneous spiking activity of poisoned excitable membrane patches is studied by use of a stochastic generalization of the Hodgkin-Huxley model. Internal noise stemming from the stochastic dynamics of individual ion channels is known to affect the collective properties of the whole ion channel cluster ...
Chow C C, Clay J R, DeFelice L J, Fox R F, G Schmid, Gammaitoni L, Goldman M S, Hille B, Hodgkin A L, Hänggi P, Hänggi P, I Goychuk, Lecar H, LeMasson G, P Hänggi, Press W H, Skaugen E, Strassberg A F   +17 more
arxiv   +5 more sources

Phα1β interaction with the Kv11.1 potassium channel in HEK293 cells transfected with the human ERG channel [PDF]

Journal of Venomous Animals and Toxins including Tropical Diseases
Background: This study examines the impact of Phα1β, a spider peptide derived from the venom of Phoneutria nigriventer, on the Kv11.1 potassium channel in HEK293 cells transfected with the human ERG potassium channel.
João B. Calixto, Adara Aurea dos Santos, Juliano Ferreira, Alessandra Hubner Souza, Célio José de Castro Junior, Marcus Vinicius Gomez   +5 more
doaj   +2 more sources

Potassium channel‐mediated NO‐induced vasodilation during maturation: Dominance of Kv7 channels [PDF]

FASEB BioAdvances
Maturation represents a process characterized by adaptive changes, particularly in the circulatory system. However, it is not known whether, in neonates, potassium channels contribute to NO‐induced vasorelaxation at all and, if so, which potassium ...
Anastasia A. Shvetsova, Dina K. Gaynullina, Peter Winkler, Paulus Wohlfart, Rudolf Schubert   +4 more
doaj   +2 more sources

Potassium channel‐related epilepsy: Pathogenesis and clinical features [PDF]

Epilepsia Open
Variants in potassium channel‐related genes are one of the most important mechanisms underlying abnormal neuronal excitation and disturbances in the cellular resting membrane potential.
Tong Zhao, Le Wang, Fang Chen
doaj   +2 more sources

Correlation studies of open and closed states fluctuations in an ion channel: Analysis of ion current through a large conductance locust potassium channel [PDF]

, 2001
Ion current fluctuations occurring within open and closed states of large conductance locust potassium channel (BK channel) were investigated for the existence of correlation. Both time series, extracted from the ion current signal, were studied by the autocorrelation function (AFA) and the detrended fluctuation analysis (DFA) methods.
A. Fuliński, D. Petracchi, E. Braun, E. Gorczyńska, E. Neher, H. Salman, H. Salman, H. Schrempf, H.E. Stanley, J. Timmer, J.W. Kantelhardt, J.W. Mozrzymas, K. Hu, Kristinka Ivanova, L.S. Liebovitch, L.S. Liebovitch, L.S. Liebovitch, M. Ausloos, M. Karplus, Marcel Ausloos, N. Vandewalle, S.B. Lowen, Sz. Mercik, Sz. Mercik, Z. Siwy, Zuzanna Siwy   +25 more
arxiv   +3 more sources

A Lipid Bilayer Formed on a Hydrogel Bead for Single Ion Channel Recordings [PDF]

Micromachines, 2020
Ion channel proteins play important roles in various cell functions, making them attractive drug targets. Artificial lipid bilayer recording is a technique used to measure the ion transport activities of channel proteins with high sensitivity and ...
Minako Hirano, Daiki Yamamoto, Mami Asakura, Tohru Hayakawa, Shintaro Mise, Akinobu Matsumoto, Toru Ide   +6 more
doaj   +3 more sources

Pharmacological Characterization of a Recombinant Mitochondrial ROMK2 Potassium Channel Expressed in Bacteria and Reconstituted in Planar Lipid Bilayers

Membranes, 2023
In the inner mitochondrial membrane, several potassium channels that play a role in cell life and death have been identified. One of these channels is the ATP-regulated potassium channel (mitoKATP).
Milena Krajewska, Adam Szewczyk, Bogusz Kulawiak, Piotr Koprowski   +3 more
doaj   +1 more source

Unique features of two potassium channels, OsKAT2 and OsKAT3, expressed in rice guard cells. [PDF]

PLoS ONE, 2013
Potassium is the most abundant cation and a myriad of transporters regulate K(+) homeostasis in plant. Potassium plays a role as a major osmolyte to regulate stomatal movements that control water utility of land plants.
Hyunsik Hwang, Jinyoung Yoon, Hyun Yeong Kim, Myung Ki Min, Jin-Ae Kim, Eun-Hye Choi, Wenzhi Lan, Young-Min Bae, Sheng Luan, Hana Cho, Beom-Gi Kim   +10 more
doaj   +1 more source

Current Challenges of Mitochondrial Potassium Channel Research

Frontiers in Physiology, 2022
In this paper, the current challenges of mitochondrial potassium channels research were critically reviewed. Even though recent progress in understanding K+ traffic in mitochondria has been substantial, some basic issues of this process remain unresolved.
Bogusz Kulawiak, Adam Szewczyk
doaj   +1 more source

Identification of key potassium channel genes of temporal lobe epilepsy by bioinformatics analyses and experimental verification

Frontiers in Neurology, 2023
One of the most prevalent types of epilepsy is temporal lobe epilepsy (TLE), which has unknown etiological factors and drug resistance. The detailed mechanisms underlying potassium channels in human TLE have not yet been elucidated.
Lin-ming Zhang, Lin-ming Zhang, Ling Chen, Ling Chen, Yi-fei Zhao, Yi-fei Zhao, Wei-mei Duan, Wei-mei Duan, Lian-mei Zhong, Lian-mei Zhong, Ming-wei Liu   +10 more
doaj   +1 more source