Results 121 to 130 of about 3,061,692 (322)
Pharmacology of Cardiac Potassium Channels [PDF]
, 2010 Cardiac K(+) channels are cardiomyocyte membrane proteins that regulate K(+) ion flow across the cell membrane on the electrochemical gradient and determine the resting membrane potential and the cardiac action potential morphology and duration. Several K(+) channels have been well studied in the human heart.
Li, GR, Dong, MQ
openaire +5 more sources
Nicorandil-Induced Hyperkalemia in a Uremic Patient
Case Reports in Medicine, 2012 Nicorandil is an antianginal agent with nitrate-like and ATP-sensitive potassium channel activator properties. After activation of potassium channels, potassium ions are expelled out of the cells, which lead to membrane hyperpolarization, closure of ...
Hung-Hao Lee +4 more
doaj +1 more source
Bulletin of Faculty of Pharmacy Cairo University, 2017 Objectives: This study was done to estimate the potential neuroprotective role of potassium channel openers in cerebral ischemia–reperfusion (IR) injury in streptozotocin (STZ) induced type-I diabetic rats (T1DR).
Anand B. Pithadia +2 more
doaj +1 more source
Brain : a journal of neurology, 2004 Patients presenting with subacute amnesia are frequently seen in acute neurological practice. Amongst the differential diagnoses, herpes simplex encephalitis, Korsakoff's syndrome and limbic encephalitis should be considered.
A. Vincent +12 more
semanticscholar +1 more source
Journal of the American Heart Association: Cardiovascular and Cerebrovascular DiseaseBackground Cardiovascular disease remains one of the leading causes of death globally. Myocardial ischemia and infarction, in particular, frequently cause disturbances in cardiac electrical activity that can trigger ventricular arrhythmias.
Ying Zhang +10 more
doaj +1 more source
A new family of outwardly rectifying potassium channel proteins with two pore domains in tandem. [PDF]
, 1995 Potassium channels catalyse the permeation of K+ ions across cellular membranes and are identified by a common structural motif, a highly conserved signature sequence of eight amino acids in the P domain of each channel's pore-forming alpha-subunit. Here
Goldstein, SA +4 more
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Biomimetic potassium selective nanopores [PDF]
arXiv, 2018 Reproducing the exquisite ion selectivity displayed by biological ion channels in artificial nanopore systems has proven to be one of the most challenging tasks undertaken by the nanopore community, yet a successful achievement of this goal offers immense technological potential.
arxiv
What have we learned from two-pore potassium channels? Their molecular configuration and function in the human heart [PDF]
, 2012 Two-pore domain potassium channels (K2P) control excitability, stabilize the resting membrane potential below firing threshold, and accelerate repolarisation in different cells.
Benyhe, Sándor +11 more
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Functional Reconstitution of a Voltage-Gated Potassium Channel in Giant Unilamellar Vesicles
PLoS ONE, 2011 Voltage-gated ion channels are key players in cellular excitability. Recent studies suggest that their behavior can depend strongly on the membrane lipid composition and physical state. In vivo studies of membrane/channel and channel/channel interactions
Sophie Aimon +5 more
semanticscholar +1 more source
KCNKØ: opening and closing the 2-P-domain potassium leak channel entails "C-type" gating of the outer pore. [PDF]
, 2001 Essential to nerve and muscle function, little is known about how potassium leak channels operate. KCNKØ opens and closes in a kinase-dependent fashion. Here, the transition is shown to correspond to changes in the outer aspect of the ion conduction pore.
Goldstein, SA, Ilan, N, Zilberberg, N
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