Results 241 to 250 of about 1,714,984 (295)

Discovery of Small-Molecule Inhibitors of the KCNQ1/Kv7.1 Potassium Channel with Virtual Screening and Functional Validation in Electrophysiological Assays and KCNQ1-Knockout Neural Stem Cells. [PDF]

ACS Chem Neurosci
Alam KA, Martí-Solans J, Schall D, Kumar S, Iqbal SM, Teigen K, Berkel S, Mauceri D, Haug BE, Liin SI, Lynagh T, Martinez A, Haavik J.   +12 more
europepmc   +1 more source

A novel near-infrared fluorescent hERG potassium channel probe for glioblastoma therapy and imaging. [PDF]

Chem Sci
Liu Z, Liu L, Ban T, Wang X, Li R, Zhang X, Wang Y, Li X, Zhang W, Li P, Tang B.   +10 more
europepmc   +1 more source

OsKAT1 is a short Shaker potassium channel involved in root-to-shoot potassium translocation and contributes to rice grain yield. [PDF]

Proc Natl Acad Sci U S A
Yang S, Nguyen TH, Fizames C, Li J, Wang S, Vernet A, Guiderdoni E, Wang S, Guo Y, Zhang W, Wei T, Huang Y, Hao D, Wang J, Sentenac H, Véry AA, Shen RF, Su Y.   +17 more
europepmc   +1 more source

Synthetic cannabinoid receptor agonists inhibit the cardiac voltage-gated potassium channel hERG

Ottosson NE, Frampton DJA, Pipatpolkai T, Norman C, Karlsson U, Jauregi-Miguel A, Venter M, Sridhar A, Larsson HP, Gréen H, Liin SI.   +10 more
europepmc   +1 more source

Inhibition of adenylyl cyclase 1 or exchange protein activated by cAMP restores ATP-sensitive potassium channel activity after chronic opioid exposure. [PDF]

Br J Pharmacol
Klein AH, Alam SMS, Johnson K, Kriner C, Beck B, Nelson B, Hill C, Meyer B, Mellang J, Watts VJ.   +9 more
europepmc   +1 more source

The Kv10.1 potassium channel, driver of hypoxia-induced EMT and breast cancer cell aggressiveness. [PDF]

Cancer Cell Int
Laîné M, Guénin S, Gutierrez L, Dehouck MP, Jonckheere N, Gosselet F, Toillon RA, Mysiorek C, Ouadid-Ahidouch H, Girault A.   +9 more
europepmc   +1 more source

Overexpression of potassium channel Kcna5 alters skeletal patterning in the zebrafish regenerating fin. [PDF]

Dev Biol
Seaver AW, Li X, Iovine MK.
europepmc   +1 more source

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Lysosomal Potassium Channels

Cell Calcium, 2022
Lysosomes are acidic membrane-bound organelles that use hydrolytic enzymes to break down material through pathways such as endocytosis, phagocytosis, mitophagy, and autophagy. To function properly, intralysosomal environments are strictly controlled by a set of integral membrane proteins such as ion channels and transporters.
Peng, Huang, Mengnan, Xu, Yi, Wu, Alia Kazim, Rizvi Syeda, Xian-Ping, Dong   +4 more
openaire   +4 more sources

Potassium channels and epilepsy

Acta Neurologica Scandinavica, 2022
With the development and application of next-generation sequencing technology, the aetiological diagnosis of genetic epilepsy is rapidly becoming easier and less expensive. Additionally, there is a growing body of research into precision therapy based on genetic diagnosis.
Kai, Gao, Zehong, Lin, Sijia, Wen, Yuwu, Jiang   +3 more
openaire   +2 more sources