Results 251 to 260 of about 274,660 (308)

Protocol to study human Kv1.2 potassium channel pathogenic sequence variants using two-electrode voltage-clamp technique. [PDF]

STAR Protoc
Manville RW, Abbott GW.
europepmc   +1 more source

Design and In Vitro Evaluation of Cross-Linked Poly(HEMA)-Pectin Nano-Composites for Targeted Delivery of Potassium Channel Blockers in Cancer Therapy. [PDF]

Gels
Civir GO, Bahadori F, Ozay O, Ergin Kızılçay G, Atesoglu S, Aldogan EH, Celik B.   +6 more
europepmc   +1 more source

Minoxidil and nebivolol restore aortic elastic fiber homeostasis in diabetic mice via potassium channel activation. [PDF]

Front Physiol
Henry A, Vanalderwiert L, Oszust F, Wahart A, Carvajal Berrio DA, Brauchle EM, Schenke-Layland K, Brinckmann J, Steenbock H, Debelle L, Six I, Faury G, Jaisson S, Gillery P, Durlarch V, Sartelet H, Maurice P, Bennasroune A, Martiny L, Duca L, Romier B, Blaise S.   +21 more
europepmc   +1 more source

<i>In silico</i> prediction of the impact of genomic variations in the small conductance calcium activated potassium channel SK3 structure and function. [PDF]

Front Neurosci
Padilla L, Del Val C, Neidre DB, Kokenge AS, Martinez JE, Teixeira AL, Zwir I, de Erausquin GA.   +7 more
europepmc   +1 more source

Rosmarinic Acid Induces Vasorelaxation via Endothelium-Dependent, Potassium Channel-Related, and Calcium-Modulated Pathways: Evidence from Rat Aortic Rings. [PDF]

Biomedicines
Sahinturk S, Isbil N.
europepmc   +1 more source

Large-Scale Structure-Based Virtual Screening Identifies Diverse K _Na 1.1 (KCNT1) Potassium Channel Inhibitors

Caseley EA, Simmons KJ, Cole BA, Flynn AJ, Muench SP, Lippiat JD.   +5 more
europepmc   +1 more source

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Lysosomal Potassium Channels

Cell Calcium, 2022
Lysosomes are acidic membrane-bound organelles that use hydrolytic enzymes to break down material through pathways such as endocytosis, phagocytosis, mitophagy, and autophagy. To function properly, intralysosomal environments are strictly controlled by a set of integral membrane proteins such as ion channels and transporters.
Peng, Huang, Mengnan, Xu, Yi, Wu, Alia Kazim, Rizvi Syeda, Xian-Ping, Dong   +4 more
openaire   +4 more sources

Potassium channels and epilepsy

Acta Neurologica Scandinavica, 2022
With the development and application of next-generation sequencing technology, the aetiological diagnosis of genetic epilepsy is rapidly becoming easier and less expensive. Additionally, there is a growing body of research into precision therapy based on genetic diagnosis.
Kai, Gao, Zehong, Lin, Sijia, Wen, Yuwu, Jiang   +3 more
openaire   +2 more sources

Potassium Channels in Cancer

2021
Neoplastic transformation is reportedly associated with alterations of the potassium transport across plasma and intracellular membranes. These alterations have been identified as crucial elements of the tumourigenic reprogramming of cells. Potassium channels may contribute to cancer initiation, malignant progression and therapy resistance of tumour ...
Katrin, Ganser, Lukas, Klumpp, Helmut, Bischof, Robert, Lukowski, Franziska, Eckert, Stephan M, Huber   +5 more
openaire   +2 more sources