Results 271 to 280 of about 274,660 (308)
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Pharmacology & Therapeutics, 1990
Many venom toxins interfere with ion channel function. Toxins, as specific, high affinity ligands, have played an important part in purifying and characterizing many ion channel proteins. Our knowledge of potassium ion channel structure is meager because until recently, no specific potassium channel toxins were known, or identified as such. This review
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Many venom toxins interfere with ion channel function. Toxins, as specific, high affinity ligands, have played an important part in purifying and characterizing many ion channel proteins. Our knowledge of potassium ion channel structure is meager because until recently, no specific potassium channel toxins were known, or identified as such. This review
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Halothane acts on many potassium channels, including a minimal potassium channel
Neuroscience Letters, 1993There has been considerable controversy over whether general anesthetics act directly on membrane proteins, and if so, whether there are uniquely sensitive protein targets upon which they act. Here, we examine the actions of halothane on a diverse collection of voltage-gated potassium channels expressed in Xenopus oocytes, and find that they are all ...
L, Zorn +4 more
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Peptide toxins and potassium channels
1990After the first detailed description of the delayed outward potassium current in squid axon by Hodgkin and Huxley (1952) it took electrophysiologists more than 20 years to realize that in addition to it several types of K+ currents can exist in the same cell and that they have a number of functions including modulation of cell excitability and ...
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PERMEATION IN POTASSIUM CHANNELS: Implications for Channel Structure
Annual Review of Biophysics and Biophysical Chemistry, 1987The SR K+ channel is a single-ion channel with a tunnel that is not very selective, while the DR and CaK channels are both more selective, multi-ion channels. The permeation mechanisms of the three channels are probably most systematically distinguished by the length of their tunnels; the SR has the shortest and the DR the longest.
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The potassium-selective channel “NaK2K”: Why is it a potassium channel?
Biophysical Journal, 2023Mohamed Shehata +3 more
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The TWIK2 Potassium Efflux Channel in Macrophages Mediates NLRP3 Inflammasome-Induced Inflammation
Immunity, 2018Anke Di, Shiqin Xiong, Zhiming Ye
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Potassium channel regulates ciliogenesis
Nature Reviews Molecular Cell Biology, 2016Paulina Strzyz, Strzyz Paulina
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Single channel studies of the ATP-regulated potassium channel in brain mitochondria
Journal of Bioenergetics and Biomembranes, 2009Piotr Bednarczyk +2 more
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Single-channel basis for the slow activation of the repolarizing cardiac potassium current, I Ks
Proceedings of the National Academy of Sciences of the United States of America, 2013Daniel Werry +2 more
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