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ATP-Sensitive Potassium Channels

Current Pharmaceutical Design, 2005
ATP-sensitive potassium (K(ATP)) channels link membrane excitability to metabolism. They are regulated by intracellular nucleotides and by other factors including membrane phospholipids, protein kinases and phosphatases. K(ATP) channels comprise octamers of four Kir6 pore-forming subunits associated with four sulphonylurea receptor subunits.
Rodrigo, GC, Standen, NB
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Potassium channels still hot

Trends in Pharmacological Sciences, 1997
The last session of the conference focused on studies which showed the formation of a channel complex consisting of KvLQT1 (a classical K+ channel protein with six transmembrane regions with one pore structure) and another component, termed minK or IsK (a small protein with a single transmembrane domain) resulting in heteromeric channel with new ...
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It's “juxta” potassium channel!

Journal of Neuroscience Research, 2004
AbstractNeuronal excitability depends on the appropriate expression and localization of ion channels. Juxtaparanodal Kv1 channels have been used as a model to study the role of neuroglial interactions in regulating the expression and localization of channels in myelinated axons.
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Peptide toxins and potassium channels

1990
After the first detailed description of the delayed outward potassium current in squid axon by Hodgkin and Huxley (1952) it took electrophysiologists more than 20 years to realize that in addition to it several types of K+ currents can exist in the same cell and that they have a number of functions including modulation of cell excitability and ...
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Structure of a Pancreatic ATP-Sensitive Potassium Channel

Cell, 2017
Ningning Li, Jing-Xiang Wu, Dian Ding
exaly  

A dominant-negative mutation in the TRESK potassium channel is linked to familial migraine with aura

Nature Medicine, 2010
M Zameel Cader   +2 more
exaly  

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