Results 301 to 310 of about 3,177,241 (350)

Advances in TRP channel drug discovery: from target validation to clinical studies

Nature Reviews Drug Discovery, 2021
Ari-Pekka Koivisto, Maria G Belvisi, Rachelle Gaudet   +2 more
exaly  

Positional cloning of a novel potassium channel gene: KVLQT1 mutations cause cardiac arrhythmias

Nature Genetics, 1996
Qing Wang, M. Curran, I. Splawski, T. Burn, J. Millholland, T. VanRaay, J. Shen, K. Timothy, Vincent Gm, Vincent Gm, T. D. Jager, P. Schwartz, J. Towbin, A. Moss, D. Atkinson, G. Landes, T. Connors, M. Keating   +17 more
semanticscholar   +1 more source

KCNQ2 and KCNQ3 potassium channel subunits: molecular correlates of the M-channel.

Science, 1998
Hao Wang, Z. Pan, W. Shi, B. S. Brown, R. Wymore, I. Cohen, J. Dixon, D. Mckinnon   +7 more
semanticscholar   +1 more source

Peptide toxins and potassium channels

1990
After the first detailed description of the delayed outward potassium current in squid axon by Hodgkin and Huxley (1952) it took electrophysiologists more than 20 years to realize that in addition to it several types of K+ currents can exist in the same cell and that they have a number of functions including modulation of cell excitability and ...
openaire   +2 more sources

Crystal structure and mechanism of a calcium-gated potassium channel

Nature, 2002
Youxing Jiang, Alice Lee, Jiayun Chen, M. Cadene, B. Chait, R. MacKinnon   +5 more
semanticscholar   +1 more source

Biophysical and molecular mechanisms of Shaker potassium channel inactivation

Science, 1990
T. Hoshi, W. N. Zagotta, R. Aldrich
semanticscholar   +1 more source

Coassembly of KVLQT1 and minK (IsK) proteins to form cardiac IKS potassium channel

Nature, 1996
M. Sanguinetti, M. Curran, A. Zou, Jiaxiang Shen, P. Spector, D. Atkinson, M. Keating   +6 more
semanticscholar   +1 more source

HERG, a human inward rectifier in the voltage-gated potassium channel family.

Science, 1995
M. Trudeau, J. Warmke, B. Ganetzky, Gail A. Robertson   +3 more
semanticscholar   +1 more source

Cardiac potassium channel subtypes: new roles in repolarization and arrhythmia.

Physiological Reviews, 2014
N. Schmitt, M. Grunnet, S. Olesen
semanticscholar   +1 more source

A novel potassium channel gene, KCNQ2, is mutated in an inherited epilepsy of newborns

Nature Genetics, 1998
Nanda A. Singh, C. Charlier, D. Stauffer, B. Dupont, R. Leach, R. Melis, G. Ronen, I. Bjerre, T. Quattlebaum, Jerome V. Murphy, Malcolm L. McHarg, D. Gagnon, T. Rosales, A. Peiffer, V. Anderson, M. Leppert   +15 more
semanticscholar   +1 more source