Results 41 to 50 of about 3,016,110 (399)
Pulmonary vasoconstrictor action of KCNQ potassium channel blockers [PDF]
, 2006 KCNQ channels have been widely studied in the nervous system, heart and inner ear, where they have important physiological functions. Recent reports indicate that KCNQ channels may also be expressed in portal vein where they are suggested to influence ...
AM Evans +23 more
core +3 more sources
Potassium Channels: Complete and Undistorted [PDF]
Current Biology, 2005 The recently determined structure of a mammalian voltage-gated potassium channel has important implications for our understanding of voltage-sensing and gating mechanisms in channels. It is also the first crystal structure of an overexpressed eukaryotic membrane protein.
Grottesi, A, Sands, Z, Sansom, MS
openaire +3 more sources
Fast inactivation in Shaker K+ channels. Properties of ionic and gating currents. [PDF]
, 1998 Fast inactivating Shaker H4 potassium channels and nonconducting pore mutant Shaker H4 W434F channels have been used to correlate the installation and recovery of the fast inactivation of ionic current with changes in the kinetics of gating current known
Bezanilla, F +4 more
core +3 more sources
Potassium channels as tumour markers [PDF]
FEBS Letters, 2006 An increasing number of ion channels are being found to be causally involved in diseases, giving rise to the new field of “channelopathies”. Cancer is no exception, and several ion channels have been linked to tumour progression. Among them is the potassium channel EAG (Ether‐a‐go‐go).
Stuhmer, Walter +4 more
openaire +4 more sources
VKCDB: Voltage-gated potassium channel database
BMC Bioinformatics, 2004 Background The family of voltage-gated potassium channels comprises a functionally diverse group of membrane proteins. They help maintain and regulate the potassium ion-based component of the membrane potential and are thus central to many critical ...
Gallin Warren J, Li Bin
doaj +1 more source
Mechanism of resveratrol-induced relaxation in the human gallbladder
BMC Complementary and Alternative Medicine, 2017 Background Resveratrol is a polyphenolic compound extracted from plants and is also a constituent of red wine. Resveratrol produces relaxation of vascular smooth muscle and may prevent cardiovascular diseases.
Ching-Chung Tsai +4 more
doaj +1 more source
Depolarization of sperm membrane potential is a common feature of men with subfertility and is associated with low fertilization rate at IVF [PDF]
, 2016 STUDY QUESTION. Are significant abnormalities in outward (K+) conductance and resting membrane potential (Vm) present in the spermatozoa of patients undertaking IVF and ICSI and if so, what is their functional effect on fertilization success?
Barratt, Christopher L. R. +9 more
core +6 more sources
American Journal of Neuroradiology, 2014 Voltage-gated potassium channel complex encephalitis is a common form of autoimmune encephalitis presenting with intractable seizures that may respond to immunotherapy.
A. Kotsenas +7 more
semanticscholar +1 more source
Kv7 and Kv11 channels in myometrial regulation. [PDF]
, 2013 Ion channels play a key role in defining myometrial contractility. Modulation of ion channel populations is proposed to underpin gestational changes in uterine contractility associated with the transition from uterine quiescence to active labour.
Iain A. Greenwood +3 more
core +2 more sources
Effect of an autism-associated KCNMB2 variant, G124R, on BK channel properties
Current Research in Physiology, 2022 BK K+ channels are critical regulators of neuron and muscle excitability, comprised of a tetramer of pore-forming αsubunits from the KCNMA1 gene and cell- and tissue-selective β subunits (KCNMB1-4).
Hans J. Moldenhauer +4 more
doaj