A high‐performance n‐type element for quasi‐solid‐state thermocells has been introduced, outperforming conventional p‐type elements and showcasing the potential to harness body heat as an energy source or power embedded sensors. This advance significantly contributes to waste thermal energy harvesting and wearable technology, paving the way for self ...
Gilyong Shin +10 more
wiley +1 more source
THE OVEREXPRESSION OF GENE ENCODING RICE POTASSIUM CHANNEL - OsТРКa INCREASES THE SALT AND DROUGHT TOLERANCE OF PLANTS [PDF]
The main aim of this study was to investigate the role of potassium TPK channel (OsTPKa) from rice in regulation of salinity and drought stresses, potassium deficiency.
S.V. Isayenkov +2 more
doaj +1 more source
ML277 specifically enhances the fully activated open state of KCNQ1 by modulating VSD-pore coupling [PDF]
Upon membrane depolarization, the KCNQ1 potassium channel opens at the intermediate (IO) and activated (AO) states of the stepwise voltage-sensing domain (VSD) activation. In the heart, KCNQ1 associates with KCNE1 subunits to form
Cui, Jianmin +4 more
core +1 more source
Stochastic Representations of Ion Channel Kinetics and Exact Stochastic Simulation of Neuronal Dynamics [PDF]
In this paper we provide two representations for stochastic ion channel kinetics, and compare the performance of exact simulation with a commonly used numerical approximation strategy.
Anderson, David F. +2 more
core +3 more sources
The MPTT‐nanozyme‐hydrogel system (Mn3O4@ChS‐HA) provides a multifunctional therapeutic strategy for intervertebral disc degeneration (IVDD), effectively targeting oxidative stress and enhancing AF repair by restoring extracellular matrix (ECM) and redox homeostasis.
Yangyang Chen +13 more
wiley +1 more source
Participation of Large Ca2+ Activated Potassium Channel in Antinociceptive Activity of Chalcone Derivative (3-(2, 5-dimethoxyphenyl)-1-(5-methylfuran-2-yl) prop-2-en-1-one) DMPF-1 Action in Mice Model [PDF]
The role of potassium channels in nociceptive activity was proposed in the past decade. Various type of potassium channel has been found to exert different action in propogation of action potential in nervous system.
Akhtar, Muhammad Nadeem +4 more
core
Expression and function of ATP-dependent potassium channels in zebrafish islet β-cells [PDF]
ATP-sensitive potassium channels (K(ATP) channels) are critical nutrient sensors in many mammalian tissues. In the pancreas, K(ATP) channels are essential for coupling glucose metabolism to insulin secretion.
Conway, Hannah +8 more
core +2 more sources
Hollow poly(heptazine imide) spheres are prepared through a novel approach that integrates hard templating with ionothermal synthesis. This method enables precise control over surface area, pore volume, hydrophilicity, light absorption, band position, and metal composition. These tunable properties facilitate the customized design of semiconductors for
Lingli Ni +10 more
wiley +1 more source
Regulation of Proliferation by a Mitochondrial Potassium Channel in Pancreatic Ductal Adenocarcinoma Cells [PDF]
Previous results link the mitochondrial potassium channel Kv1.3 (mitoKv1.3) to the regulation of apoptosis. By synthesizing new, mitochondria-targeted derivatives (PAPTP and PCARBTP) of PAP-1, a specific membrane-permeant Kv1.3 inhibitor, we have ...
Amigorena +48 more
core +2 more sources
Porous silicon nanoparticles (PSiNPs) reprogram macrophage endocytosis of manganese@albumin‐based TLR4 nanoagonists, driving TRIF‐biased TLR4 signaling, eliciting robust proinflammatory responses, and potentiating macrophage‐mediated immunotherapeutic effects against NSCLC.
Xiaomei Zhang +9 more
wiley +1 more source

