Results 81 to 90 of about 456,361 (296)

Bioinspired Stabilization of Fluorescent Au@SiO2 Tracers for Multimodal Biological Imaging

Advanced Functional Materials, EarlyView.
This study demonstrates a bioinspired stabilization strategy for fluorescent gold‐silica nanoparticles. Inspired by natural biosilica maturation, high‐temperature calcination transforms the silica shells, preventing dissolution in cell culture media and intracellular environments.
Wang Sik Lee, Henry Lee, Patricia Taladriz‐Blanco, Dimitri Vanhecke, Barbara Rothen‐Rutishauser, Alke Petri‐Fink   +5 more
wiley   +1 more source

Regulation of mitochondrial potassium BKCa channel by naringenin derivatives: application of a new cellular model

European Journal of Medicinal Chemistry Reports
Mitochondrial potassium (mitoK) channels play a crucial role in mitochondrial and cellular physiology. One of the best described mitoK channels is the mitochondrial large-conductance calcium-activated potassium (mitoBKCa) channel.
Aleksandra Sęk, Silvia Cammarone, Rafał P. Kampa, Karolina Pytlak, Barbara Kalenik, Joanna Lewandowska, Francesca Ghirga, Isabella Romeo, Omar Atrooz, Piotr Bednarczyk, Adam Szewczyk, Bruno Botta, Deborah Quaglio, Bogusz Kulawiak   +13 more
doaj   +1 more source

Distinct Distribution Patterns of Potassium Channel Sub-Units in Somato-Dendritic Compartments of Neurons of the Medial Superior Olive

Frontiers in Cellular Neuroscience, 2019
Coincidence detector neurons of the medial superior olive (MSO) are sensitive to interaural time differences in the range of a few tens of microseconds. The biophysical basis for this remarkable acuity is a short integration time constant of the membrane,
Alisha L. Nabel, Alisha L. Nabel, Alexander R. Callan, Alexander R. Callan, Sarah A. Gleiss, Sarah A. Gleiss, Nikolaos Kladisios, Christian Leibold, Felix Felmy, Felix Felmy   +9 more
doaj   +1 more source

A Lipid Bilayer Formed on a Hydrogel Bead for Single Ion Channel Recordings

Micromachines, 2020
Ion channel proteins play important roles in various cell functions, making them attractive drug targets. Artificial lipid bilayer recording is a technique used to measure the ion transport activities of channel proteins with high sensitivity and ...
Minako Hirano, Daiki Yamamoto, Mami Asakura, Tohru Hayakawa, Shintaro Mise, Akinobu Matsumoto, Toru Ide   +6 more
doaj   +1 more source

Upregulation of Functional Kv11.1 Isoform Expression by Inhibition of Intronic Polyadenylation with Antisense Morpholino Oligonucleotides

, 2014
The KCNH2 gene encodes the Kv11.1 potassium channel that conducts the rapidly activating delayed rectifier current in the heart. KCNH2 pre-mRNA undergoes alternative processing; intron 9 splicing leads to the formation of a functional, full-length Kv11 ...
Gong, Qiuming, Stump, Matthew R., Zhou, Zhengfeng   +2 more
core   +1 more source

The selectivity, voltage-dependence and acid sensitivity of the tandem pore potassium channel TASK-1 : contributions of the pore domains [PDF]

, 2007
We have investigated the contribution to ionic selectivity of residues in the selectivity filter and pore helices of the P1 and P2 domains in the acid sensitive potassium channel TASK-1.
A Sali, AD O’Connell, AJ Patel, C Girard, C Karschin, CMB Lopes, CMB Lopes, D Bichet, D Bockenhauer, D Kim, D Kim, D Leonoudakis, DA Bayliss, DA Doyle, DL Prole, F Bezanilla, F Duprat, F Lesage, F Lesage, F Maingret, G Czirják, G Czirják, G Yellen, I Ashmole, I Lauritzen, I So, I. Ashmole, J Lopez-Barneo, JF Cordero-Morales, JF Cordero-Morales, JG Starkus, K. H. Yuill, KH Yuill, KJ Buckler, L Heginbotham, L Pei, LJ McGuffin, M Taglialatela, M. J. Sutcliffe, MJ Morton, ML Chapman, N Decher, N Zilberberg, P Hadjú, P. J. Stansfeld, P. R. Stanfield, PR Stanfield, R MacKinnon, R Reyes, S Rajan, S Somodi, SA Goldstein, SC Tosatto, SJ Kehl, TJ Jentsch, TW Claydon, X Li, Y Kim, Y Zhou, ZA Wood   +59 more
core   +2 more sources

Nucleation‐Controlled Reconstruction of CuOx for Selective CO2 Electroreduction

Advanced Functional Materials, EarlyView.
The ratio of oxygen vacancies (Ov) and exposed Cu2O (111)/(200) of CuOx precatalyst is modulated by nucleation control of Cu(OH)2 precursor. Low Ov ratio and high ratio of Cu2O (111)/(200) in slow‐nucleated CuOx reconstructs to high‐coordinated oxide‐derived copper (OD‐Cu) during electrochemical CO2 reduction reaction (CO2RR) and exhibits enhanced ...
Ying Ying Ch'ng, Zhipeng Ma, Ming Zhang, Shujie Zhou, Varun Kundi, Priyank Vijaya Kumar, Wenyu Zhong, Yuwei Yang, Jitraporn Vongsvivut, Qinfen Gu, Xiaoxuan Luo, Lixue Jiang, Rahman Daiyan, Zhaojun Han, Rose Amal   +14 more
wiley   +1 more source

Activation of KATP channels in pain modulation: a systematic review of preclinical studies

Frontiers in Physiology
ObjectiveTo systematically review the involvement of KATP channel activation in pain modulation in preclinical studies.BackgroundKATP channels are expressed at several levels in the spinal and trigeminal pain pathways, where they seem to modulate ...
Signe Schønning Beich, Lili Kokoti, Mohammad Al-Mahdi Al-Karagholi, Mohammad Al-Mahdi Al-Karagholi   +3 more
doaj   +1 more source

Theoretical Predictions of Superconductivity in Alkali Metals under High Pressure

, 2006
We calculated the superconductivity properties of alkali metals under high pressure using the results of band theory and the rigid-muffin-tin theory of Gaspari and Gyorffy.
D. A. Papaconstantopoulos, D. A. Young, Lei Shi, U. Schwarz   +3 more
core   +1 more source

Color Routing and Beam Steering of Single‐Molecule Emission with a Spherical Silicon Nanoantenna

Advanced Functional Materials, EarlyView.
We experimentally demonstrate broadband directional emission from single molecules using a single spherical silicon nanoparticle assembled via DNA origami. By varying nanoparticle (NP) size and emitter position, we achieve unidirectional emission, beam steering, and color routing at the nanoscale, revealing modal interference as the underlying ...
María Sanz‐Paz, Nicole Siegel, Guillermo Serrera, Javier González‐Colsa, Fangjia Zhu, Karol Kołątaj, Minoru Fujii, Hiroshi Sugimoto, Pablo Albella, Guillermo P. Acuna   +9 more
wiley   +1 more source