Results 211 to 220 of about 247,875 (263)
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An Adenovirus Vaccine Potency Test
The Journal of Immunology, 1961Summary Adenovirus vaccine potency estimates, based upon immune responses following multiple injections of fluid vaccine, were unreliable. As an alternative, a potency test based upon a single injection of vaccine with oil-adjuvant is described.
H, TINT, J, STONE
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Comparisons of outlier tests for potency bioassays
Pharmaceutical Statistics, 2019SummaryPotency bioassays are used to measure biological activity. Consequently, potency is considered a critical quality attribute in manufacturing. Relative potency is measured by comparing the concentration‐response curves of a manufactured test batch with that of a reference standard. If the curve shapes are deemed similar, the test batch is said to
Perceval Sondag +4 more
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Potency testing of acellular pertussis vaccines
Vaccine, 1992The laboratory assessment of the potential of acellular pertussis vaccines to protect against human disease is a major problem. The mouse intracerebral challenge test, which is the accepted potency assay for whole cell pertussis vaccines, is not suitable for testing acellular vaccines, and more recently developed murine respiratory infection assays ...
A, Robinson, S G, Funnell
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Potency Testing of Live Measles Vaccine
Archives of Pediatrics & Adolescent Medicine, 1962The preceding series of papers has furnished information pertaining to the number of infectious units of attenuated measles virus needed to immunize susceptible children. These presentations have also touched on the question of the optimum virus content of the live vaccine, both as it leaves the hands of the manufacturer and at the actual moment of ...
H M, MEYER +3 more
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American Journal of Veterinary Research, 1972
SUMMARY A relationship was shown to exist between agglutination titers and immunologic responses of cattle vaccinated with experimentally produced and commercially available Clostridium chauvoei-containing bacterins. The immunity of vaccinated and control cattle was challenged with C. chauvoei spore F.
M E, Macheak, K D, Claus, S E, Maloy
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SUMMARY A relationship was shown to exist between agglutination titers and immunologic responses of cattle vaccinated with experimentally produced and commercially available Clostridium chauvoei-containing bacterins. The immunity of vaccinated and control cattle was challenged with C. chauvoei spore F.
M E, Macheak, K D, Claus, S E, Maloy
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A comparison of methods for the potency test of rubella vaccine
Journal of Biological Standardization, 1977Forty titrations of HPV/77 rubella vaccine by the cytopathic effect microassay and 26 titrations by the tube interference test were performed. The variance analysis of the results demonstrated that the cytopathic effect microassay is a more reliable method for the potency test of rubella vaccine.
M, Rapicetta, R, Santoro, M E, Grandolfo
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A review of the effectiveness of vaccine potency control testing
International Journal for Parasitology, 2003The use of potency control testing is a valuable tool for testing the actual relative strength of manufactured assembly lots of vaccine. Biological-based manufacturing methods are inherently variable and potency testing is a tool to ensure lot-to-lot consistency of commercial vaccines.
David Scott, McVey +2 more
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A One-Dose Potency Test for Poliomyelitis Vaccine
The Journal of Immunology, 1965Summary Studies leading to the development and use of a one-dose potency test for poliomyelitis vaccine are described. The test is based on the measurement of neutralizing antibody in the serum of 6-week-old chickens that received one dose of a single dilution of vaccine.
R M, VANFRANK +5 more
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A Guinea Pig Potency Test for Adenovirus Vaccine
The Journal of Immunology, 1960Summary An assay for potency of adenovirus vaccine in guinea pigs based on the antigen extinction principle is described. The potency test values in repeat titrations were reproducible within a maximal 7-fold range. Further need for control with a standard reference vaccine is indicated. Potency values for a number of vaccines of diverse
L N, BINN, M R, HILLEMAN
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A potency test for live Newcastle disease vaccines
Journal of Biological Standardization, 1980The potency of live Newcastle disease vaccines was assessed by means of a multi-point challenge assay in vaccinated chicks. The assay was shown to give reproducible results and to be capable of detecting significant differences between the protective capacities of various vaccines.
D H, Thornton, C N, Hebert
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