Results 221 to 230 of about 241,473 (261)
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A Guinea Pig Potency Test for Adenovirus Vaccine
The Journal of Immunology, 1960Summary An assay for potency of adenovirus vaccine in guinea pigs based on the antigen extinction principle is described. The potency test values in repeat titrations were reproducible within a maximal 7-fold range. Further need for control with a standard reference vaccine is indicated. Potency values for a number of vaccines of diverse
L N, BINN, M R, HILLEMAN
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A One-Dose Potency Test for Poliomyelitis Vaccine
The Journal of Immunology, 1965Summary Studies leading to the development and use of a one-dose potency test for poliomyelitis vaccine are described. The test is based on the measurement of neutralizing antibody in the serum of 6-week-old chickens that received one dose of a single dilution of vaccine.
R M, VANFRANK +5 more
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Rabies Vaccine Potency and Stability Testing
1988It is 100 years since Louis Pasteur carried out the first immunization of humans against rabies virus infection. Although great advances have been made in the development of more effective and purified vaccines, vaccines produced in adult or suckling animal nervous tissue are still in use in many countries.
Morag Ferguson +2 more
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Potency testing of killed polio vaccine in rats.
Developments in biological standardization, 1980Various laboratory animal species were considered for testing the potency of killed poliovaccine. The rat appeared most suitable for obtaining quantitative information by measuring the titre of the antibody response. There was, in general, a good correlation between antibody response in rats and D-antigen titre.
van Steenis, G +2 more
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Potency testing of bovine tuberculins.
Developments in biological standardization, 1987The diagnosis of bovine tuberculosis is based on the intradermal tuberculin test. Therefore in eradication campaigns HCSM or PPD tuberculins with high potency and maximal specificity per cattle dose are needed. In quality control and standardization assays the PPD tuberculins have the advantage that the protein content can serve as a basis for ...
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Release potency tests of hepatitis vaccines.
Developments in biological standardization, 1999SmithKline Beecham Biologicals produces two vaccines against hepatitis: hepatitis B (Engerix-B) introduced in 1986 and hepatitis A (Havrix) introduced in 1991. Using these two examples, we demonstrate the long and gradual transition process towards an in vitro release test for potency and a significant decrease in the number of animals needed for ...
J, Descamps +5 more
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Potency testing of bacterial vaccines for human use
Veterinary Microbiology, 1993The potency tests for bacterial vaccines are quite diverse. For some products (pertussis, cholera, anthrax, typhoid and BCG vaccines) these are specified as Additional Standards in the Code of Federal Regulations. For other products (tetanus and diphtheria toxoids, plague vaccine) the testing is done according to so-called Minimum Requirements, which ...
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Current Status of Rabies Vaccine Potency Testing
1985The method currently recommended for potency assays of rabies vaccine is the mouse protection test, the NIH test. There is, however, a need for a reliable in vitro potency assay to complement the results of these in vivo assays.
M. Ferguson, G. C. Schild
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Increased memory B cell potency and breadth after a SARS-CoV-2 mRNA boost
Nature, 2022Frauke Mücksch, Zijun Wang, Alice Cho
exaly