Results 241 to 250 of about 469,402 (307)

Strength through diversity: how cancers thrive when clones cooperate

Molecular Oncology, EarlyView.
Intratumor heterogeneity can offer direct benefits to the tumor through cooperation between different clones. In this review, Kuiken et al. discuss existing evidence for clonal cooperativity to identify overarching principles, and highlight how novel technological developments could address remaining open questions.
Marije C. Kuiken, Maartje Witsen, Emile E. Voest, Krijn K. Dijkstra   +3 more
wiley   +1 more source

An Aptamer-Based EXACT Anticoagulant as a Sustainable, Animal-Free Alternative to Unfractionated Heparin. [PDF]

Adv Sci (Weinh)
Yu H, Pitoc G, Zhang M, Clancy J, Frederiksen J, Yan A, Francis S, Sullenger R, Rempel R, Gammell S, Caiazzi J, Sullenger BA.   +11 more
europepmc   +1 more source

Detection of circulating tumor DNA in colorectal cancer patients using a methylation‐specific droplet digital PCR multiplex

Molecular Oncology, EarlyView.
We developed a cost‐effective methylation‐specific droplet digital PCR multiplex assay containing tissue‐conserved and tumor‐specific methylation markers. The assay can detect circulating tumor DNA with high accuracy in patients with localized and metastatic colorectal cancer.
Luisa Matos do Canto, Louise Raunkilde, Jan Lindebjerg, Mads Malik Aagaard, Christina Therkildsen, Jakob Kleif, Lars Henrik Jensen, Torben Frøstrup Hansen, Rikke Fredslund Andersen   +8 more
wiley   +1 more source

Conference report WHO informal consultation on the draft WHO Guideline on the phasing out of animal tests for the quality control of biological products.

Biologicals
Feavers I, Lei D, Milne C, Knezevic I, Zhou T, Kim E.   +5 more
europepmc   +1 more source

In Vitro Pharmacology of Mitragynine at α-Adrenoceptors. [PDF]

ACS Chem Neurosci
Chen Y, Seto J, Obeng S, Mottinelli M, Mukhopadhyay S, Tyagi R, Hampson AJ, McCurdy CR, McMahon LR, Moniri NH, Canal CE.   +10 more
europepmc   +1 more source

Discovery of an allosteric binding site for anthraquinones at the human P2X4 receptor. [PDF]

Nat Commun
Nagel J, Namasivayam V, Weinhausen S, Sierra-Marquez J, Baqi Y, Al Musawi HAM, Abdelrahman A, Vaaßen VJ, Schlegel JG, Taplick L, Torp J, Kubicek J, Maertens B, Geyer M, Claff T, Nicke A, Hagelueken G, Müller CE.   +17 more
europepmc   +1 more source

Prolintane analogs as hybrid monoamine transporter ligands: Structural determinants and species differences. [PDF]

J Biol Chem
Kastner N, Islam MN, Dybek M, Roth E, Heisinger S, Holy M, Jäntsch K, Walther D, Stockner T, Baumann MH, Brandt SD, Wallach J, Sitte HH, Kudlacek O.   +13 more
europepmc   +1 more source

Person - A Key Concept for Ethics [PDF]

, 1989
Doran, Kevin
core   +1 more source

Self-disturbance in first-episode psychosis: Theoretical framework and potential cannabis interactions - a systematic review. [PDF]

Front Psychiatry
Ricci V, De Berardis D, Martinotti G, Maina G.   +3 more
europepmc   +1 more source

The Potential of Plant Secondary Metabolites as Bread Mould Inhibitors: Exploring Their Individual and Combined Antifungal Effect. [PDF]

Foods
Lepoutre A, Debonne E, Van Genechten W, Martini S, Van Dijck P, Devlieghere F.   +5 more
europepmc   +1 more source