Results 221 to 230 of about 247,875 (263)

Relative mutagenic potencies determined in the micronucleus test

Journal of Theoretical Biology, 1978
Abstract Data from two publications which include dose-response data were subject to model fitting using a Poisson distribution and a linear dose-response function. In Swiss mice, acetylaminofluorene was the weakest mutagen tested. Aflatoxin B 1 , 3-methylcholanthrene and dimethylnitrosamine were 66, 14, and 140 times as potent, respectively.
M A, Friedman, W H, Carter, J, Staub, A, Segreti   +3 more
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Simple potency test for LH-RH preparations

Journal of Biological Standardization, 1980
Proestrous rats, pretreated with fluphenazine dihydrochloride (FD) to block ovulation, were used to compare the ovulation-inducing activity of two synthetic LH-RH preparations; one was received from the National Institute for Biological Standards and Control labelled Gonadorelin acetate (77/596) and the other one was prepared in Ayerst Research ...
U K, Banik, M L, Givner
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A collaborative study on the potency testing of antirabies globulin

Journal of Biological Standardization, 1975
Studies have shown that Rabies Immune Globulin, Human, used in combination with vaccine, is most effective when given within a relatively narrow dose range. A dosage of 20 International Units (i.u.) per kg gave satisfactory results while 10 i.u./kg appeared to be insufficient for early protection and 40 i.u./kg may have interfered with optimal antibody
E A, Fitzgerald, G M, Baer, V F, Cabasso, R F, Vallancourt   +3 more
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A Simple Potency Test for Foot-and-Mouth Disease Vaccines in Mice and Comparison of Results with those of Potency Tests in Cattle

Zentralblatt für Veterinärmedizin Reihe B, 2010
Summary Adult mice vaccinated with monovalent foot-and-mouth disease vaccines prepared according to the Frenkel method developed complement fixing antibodies demonstrable by a modified direct complement-fixation test, which was called “complement-consumption test” (CCT) in distinction from conventional CFT.
E, Traub, P, Thein, F, Kesting
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Potency testing of killed polio vaccine in rats.

Developments in biological standardization, 1980
Various laboratory animal species were considered for testing the potency of killed poliovaccine. The rat appeared most suitable for obtaining quantitative information by measuring the titre of the antibody response. There was, in general, a good correlation between antibody response in rats and D-antigen titre.
van Steenis, G, van Wezel, AL, Sekhuis, VM   +2 more
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Proposed Potency Testing of Smallpox Vaccine

The Journal of Immunology, 1961
Summary and Conclusions From the results of the studies described here, it is obvious that immediate application of titration in rabbit kidney tissue culture is a valid measure of smallpox vaccine potency only for the virus strain and passage levels employed.
V J Cabasso, I F Moore, M R Stebbins
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Potency testing of bacterial vaccines for human use

Veterinary Microbiology, 1993
The potency tests for bacterial vaccines are quite diverse. For some products (pertussis, cholera, anthrax, typhoid and BCG vaccines) these are specified as Additional Standards in the Code of Federal Regulations. For other products (tetanus and diphtheria toxoids, plague vaccine) the testing is done according to so-called Minimum Requirements, which ...
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Rabies Vaccine Potency and Stability Testing

1988
It is 100 years since Louis Pasteur carried out the first immunization of humans against rabies virus infection. Although great advances have been made in the development of more effective and purified vaccines, vaccines produced in adult or suckling animal nervous tissue are still in use in many countries.
Morag Ferguson, Valerie Seagroatt, G. C. Schild   +2 more
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Potency testing of bovine tuberculins.

Developments in biological standardization, 1987
The diagnosis of bovine tuberculosis is based on the intradermal tuberculin test. Therefore in eradication campaigns HCSM or PPD tuberculins with high potency and maximal specificity per cattle dose are needed. In quality control and standardization assays the PPD tuberculins have the advantage that the protein content can serve as a basis for ...
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Planarian stem cells specify fate yet retain potency during the cell cycle

Cell Stem Cell, 2021
Omri Wurtzel, Peter W Reddien
exaly