Going viral − Virus‐targeting nanobodies for research, diagnostics and therapy
The increasing prevalence of viral diseases represents a major threat for global human health. Nanobodies, small binding fragments derived from camelid heavy‐chain antibodies, offer versatile tools for viral research, diagnostics, and antiviral therapy.
Domenic Ebert, Ulrich Rothbauer
wiley +1 more source
Highlights A versatile material-antimony potassium tartrate is added to wide-bandgap perovskite cells for the first time. Inverted wide-bandgap perovskite solar cells with a structure of ITO/MeO-2PACz/perovskite/C60/ALD-SnO2/Cu yield a champion power ...
Xuzhi Hu +9 more
doaj +1 more source
The influence of training status, age, and muscle fiber type on cycling efficiency and endurance performance. [PDF]
The purpose of this study was to assess the influence of age, training status, and muscle fiber-type distribution on cycling efficiency. Forty men were recruited into one of four groups: young and old trained cyclists, and young and old untrained ...
Wiles, J. +15 more
core +1 more source
Vacuolar H+‐ATPase (V‐ATPase) is a multisubunit rotary proton pump that acidifies intracellular compartments. Using elastic network models, we identified conserved hinge residues that govern its large‐scale functional motions. We show that intrinsically encoded ‘soft modes’ drive critical functional transitions, including rotary catalysis and ...
Diksha Parwana +3 more
wiley +1 more source
Applications of the genetic algorithm optimisation approach in the design of high efficiency microwave class E power amplifiers [PDF]
In this thesis Genetic Algorithm Optimisation Methods (GA) is studied and for the first time used to design high efficiency microwave class E power amplifiers (PAs) and associated load patch antennas.
Lu, Qing
core
Unlocking the potential of cell‐permeable nanobodies for intracellular applications
This review outlines current strategies for delivery of nanobodies into cells and highlights recent examples of functional applications. By addressing and manipulating intracellular targets, these molecules hold great potential for treating cancer, respiratory diseases and neurological disorders, making this a vibrant area of research in the biomedical
Mariona Gené‐Verdés +2 more
wiley +1 more source
Data Value-Added Service Comprehensive Evaluation Method on the Performance of Power System Big Data
With the development of digital economy, the integration and secure sharing of energy big data have become pivotal in driving innovation across the energy production, distribution, and consumption sectors.
Hao Zhang +6 more
doaj +1 more source
The Collection Efficiency of the Value Added Tax: Theory and International Evidence [PDF]
This paper evaluates the political economy and structural factors explaining the collection efficiency of the Value Added Tax [VAT]. We consider the case where the collection efficiency is determined by the probability of audit and by the penalty on ...
Yothin Jinjarak, Joshua Aizenman
core
Comparing the paths of Hedgehog release in artificial and natural settings
Hh morphogens require solubilization factors to overcome their tight association with the plasma membrane and signal to distant cells, but the precise functions of these factors are controversial. Here, we use published in vivo observations as the most relevant evidence to test their suggested functions and discuss contradictions and gaps between in ...
Janna Puschmann, Kay Grobe
wiley +1 more source
Development of rugged 2 GHz power bars delivering more than 100 W and 60% power added efficiency
S.2398-2403In this work we systematically study the structural, optical and electrical properties of AlGaN/GaN heterostructures grown by MOCVD 3-inch on SiC substrates Thefinally developed HEMTs demonstrate excellent highvoltage stability, high power ...
Müller, Stefan +13 more
core +1 more source

