Results 91 to 100 of about 339,663 (292)

MiR‐513a promotes human erythroid differentiation by modulating c‐Jun

FEBS Open Bio, EarlyView.
During early human erythropoiesis, miR‐513a promoted erythroid differentiation in primary human CD34+ hematopoietic stem‐progenitor cells and human TF‐1 erythroleukemic cells by indirectly decreasing c‐Jun and phospho‐c‐Jun expression, which are associated with increased GATA1 expression.
MinJung Kim, Brittany Taylor, Shannon Bolten, Christian L. Eberly, Mahliya Abdurahman, T. Michael Creed, Acong Yang, Taylor L. Hatchet, Tristan Dyson, Shuo Gu, Curt I. Civin, Tami J. Kingsbury   +11 more
wiley   +1 more source

Development of a HgCdTe photomixer and impedance matched GaAs FET amplifier [PDF]

A research program for the development of a 10.6 micron HgCdTe photodiode/GaAs field effect transistor amplifier package for use at cryogenic temperatures (77k).
Paulauskas, W. A., Shanley, J. F., Taylor, D. R.   +2 more
core   +1 more source

Mass spectrometry based identification of AMP‐O‐Tris generated by Thermococcus onnurineus Cas10

FEBS Open Bio, EarlyView.
Isolated Thermococcus onnurineus Cas10 generates the noncanonical ATP‐derived product AMP‐O‐Tris while in Tris‐containing buffer as identified via mass spectrometry, revealing relaxed nucleophile selectivity under isolated conditions. These findings suggest that multiprotein Csm complex assembly restricts Cas10 reactivity toward canonical cyclic ...
Su‐Jin Lee, Ga Seul Lee, JinHan Kim, Kwang‐Hyun Park, Seong‐Ryung Go, Jeong Hee Moon, Eui‐Jeon Woo   +6 more
wiley   +1 more source

Natural Products as Geroprotective Modulators in Diabetic Nephropathy: A Mechanistic Framework Integrating Aging Hallmarks and the AMPK–SIRT1–Nrf2 Axis

Aging and Cancer, EarlyView.
Natural products target the aging kidney in diabetic nephropathy by restoring the AMPK–SIRT1–Nrf2 axis, reducing oxidative stress, inflammation, fibrosis, and cellular senescence while enhancing mitochondrial biogenesis and antioxidant defenses.
Sherif Hamidu, Latif Adams, Eunice Ampem‐Danso, Justice Kumi, Abigail Aning, Fatima Hamidu, Mustapha Abdul Mumin Mohammed, Ayuba Nii Darku Ankrah, Seth Kwabena Amponsah   +8 more
wiley   +1 more source

The 100 W class A power amplifier for L-band T/R module

Journal of Telecommunications and Information Technology, 2002
In the paper a balanced high power amplifier with class A silicon bipolar transistors for L-band T/R module is described. The amplifier was designed for maximum power and minimum transmitance distortions.
Wojciech Wojtasiak, Daniel Gryglewski, Edward Sędek   +2 more
doaj   +1 more source

Passive alignment stability and auto-alignment of multipass amplifiers based on Fourier transforms

, 2019
The stability properties of Fourier-based multipass amplifier to misalignments (tilts) of its optical components has been investigated. For this purpose, a method to quantify the sensitivity to tilts based on the amplifier small signal gain has been ...
Antognini, Aldo, Kirch, Klaus, Knecht, Andreas, Marszalek, Miroslaw, Nez, Francois, Nuber, Jonas, Pohl, Randolf, Schuhmann, Karsten, Schulthess, Ivo, Sinkunaite, Laura, Zeyen, Manuel   +10 more
core   +3 more sources

Patterns of Postictal Abnormalities in Relation to Status Epilepticus in Adults

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Abnormalities on peri‐ictal diffusion‐weighted magnetic resonance imaging (DWI‐PMAs) are well‐established for patients with status epilepticus (SE), but knowledge on patterns of DWI‐PMAs and their prognostic impact is sparse. Methods This systematic review and individual participant data meta‐analysis included observational studies ...
Andrea Enerstad Bolle, Silvana Sarria‐Estrada, Thomas Bonduelle, Bertram Daniel Dynesen, Manuel Toledo, Zhu Chung Che, Kjell Heuser, Anastasios Chatzikonstantinou, Jérôme Aupy, Udaya Seneviratne, Estevo Santamarina Perez, Christoph Patrick Beier   +11 more
wiley   +1 more source

CX3CL1 in Early Detection of Alzheimer's Disease: Plasma Dynamics Across Age and Disease Stages

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Backgrounds Alzheimer's disease (AD) is characterized by amyloid‐beta plaques, tau tangles, and neuroinflammation. C‐X3‐C motif chemokine ligand 1 (CX3CL1, also known as fractalkine), a neuroimmune chemokine implicated in AD pathogenesis, shows inconsistent alterations in plasma/serum across studies.
Ling Wang, Yujie Liu, Fei Li, Xuelin Li, Lanlan Li, Jie Zhang, Yali Xu   +6 more
wiley   +1 more source

A High Power Frequency-Stabilized Tunable Two-Frequency Diode Laser System for the Generation of Coherent THz-Waves by Photomixing [PDF]

, 1998
A tunable two-frequency high-power diode laser system at 850 nm for terahertz (Thz)-wave generation by photomixing in low-temperature-grown GaAs photo-conductors has been developed. The difference frequency is obtained through a three laser system, where
Blake, Geoffrey A., Chen, Pin, Matsuura, Shuji, Pearson, J. C., Pickett, Herbert M.   +4 more
core  

Design and characterization of a lumped element single-ended superconducting microwave parametric amplifier with on-chip flux bias line

, 2013
We demonstrate a lumped-element Josephson parametric amplifier, using a single-ended design that includes an on-chip, high-bandwidth flux bias line. The amplifier can be pumped into its region of parametric gain through either the input port or through ...
Barends, Rami, Bochmann, Joerg, Chen, Yu, Chen, Zijun, Chiaro, Ben, Cleland, Andrew, Dunsworth, Andrew, Jeffrey, Evan, Kelly, Julian, Martinis, John, Megrant, Anthony, Mutus, Josh, Neill, Charles, O'Malley, Peter, Roushan, Pedram, Sank, Daniel, Siddiqi, Irfan, Vainsencher, Amit, Vijayaraghavan, Rajamani, Wenner, James, White, Ted   +20 more
core   +1 more source