Results 71 to 80 of about 339,663 (292)

KLK7 overexpression promotes an aggressive phenotype and facilitates peritoneal dissemination in colorectal cancer cells

open access: yesFEBS Open Bio, EarlyView.
KLK7, a tissue kallikrein‐related peptidase, is elevated in advanced colorectal cancer and associated with shorter survival. High KLK7 levels in ascites correlate with peritoneal metastasis. In mice, KLK7 overexpression increases metastasis. In vitro, KLK7 enhances cancer cell proliferation, migration, adhesion, and spheroid formation, driving ...
Yosr Z. Haffani   +6 more
wiley   +1 more source

Domain associated with zinc fingers‐containing NF90‐NF45 complex inhibits m6A modification of primary microRNA by suppressing METTL3/14 activity

open access: yesFEBS Open Bio, EarlyView.
NF90–NF45 functions as a negative regulator of methyltransferase‐like 3/14 (METTL3/14)‐mediated N6‐methyladenosine (m6A) modification on primary microRNAs (pri‐miRNAs). NF90–NF45 binds to anti‐oncogenic pri‐miRNAs and inhibits their m6A modification, thereby suppressing the biogenesis of anti‐oncogenic miRNAs.
Takuma Higuchi   +6 more
wiley   +1 more source

Design and Simulation for a High-efficiency Class-B Power Amplifier

open access: yesMATEC Web of Conferences, 2017
A class-B power amplifier with high output power and high power added efficiency (PAE) is designed in this paper. Based on the ADS tools of load-pull and source-pull, the optimal load impedance and source impedance can be obtained, respectively.
Jiang Wei, Lin Qian, Wu Haifeng
doaj   +1 more source

Design of a three-phase 100 A linear amplifier for power-hardware-in-the-loop machine emulation

open access: yesThe Journal of Engineering, 2019
Here, the setup of a three-phase 100 A linear amplifier is proposed. This work focusses on the use of this linear amplifier as power element for machine-emulation.
Manuel Fischer   +4 more
doaj   +1 more source

Enzymatic degradation of biopolymers in amorphous and molten states: mechanisms and applications

open access: yesFEBS Open Bio, EarlyView.
This review explains how polymer morphology and thermal state shape enzymatic degradation pathways, comparing amorphous and molten biopolymer structures. By integrating structure–reactivity principles with insights from thermodynamics and enzyme engineering, it highlights mechanisms that enable efficient polymer breakdown.
Anđela Pustak, Aleksandra Maršavelski
wiley   +1 more source

Tumor‐stromal crosstalk and macrophage enrichment are associated with chemotherapy response in bladder cancer

open access: yesFEBS Open Bio, EarlyView.
Chemoresistance in bladder cancer: Macrophage recruitment associated with CXCL1, CXCL5 and CXCL8 expression is characteristic of Gemcitabine/Cisplatin (Gem/Cis) Non‐Responder tumors (right side) while Responder tumors did not show substantial tumor‐stromal crosstalk (left side). All biological icons are attributed to Bioicons: carcinoma, cancerous‐cell‐
Sophie Leypold   +11 more
wiley   +1 more source

A Transformer-Based Dual-Mode Ka-Band CMOS Power Amplifier With Enhanced Back-Off Efficiency

open access: yesIEEE Journal of Microwaves
This paper presents the differential-to-single-ended load-modulated (DISEL)-power amplifier, a transformer-based dual-mode Ka-band CMOS power amplifier designed to enhance power-added efficiency (PAE) under output back-off conditions while maintaining ...
Hyunsoo Kim, Jaeyong Lee, Changkun Park
doaj   +1 more source

Mathematical model of optical amplifier using nonlinear stimulated Brillouin scattering (SBS) in optical fiber

open access: yesمجلة بغداد للعلوم, 2007
We demonstrate the results of a mathematical model for investigation the nonlinear Stimulated Brillouin Scattering (SBS), which can be employed to achieve high optical amplifier.
Baghdad Science Journal
doaj   +1 more source

A 1-W, 30-ghz, CPW Amplifier for ACTS Small Terminal Uplink [PDF]

open access: yes
The progress is described of the development of a 1 W, 30 GHz, coplanar waveguide (CPW) amplifier for the Advanced Communication Technology Satellite (ACTS)Small Terminal Uplink.
Simons, Rainee N., Taub, Susan R.
core   +1 more source

A Power Efficient Audio Amplifier Combining Switching and Linear Techniques [PDF]

open access: yes, 1998
Integrated Class D audio amplifiers are very power efficient, but require an external filter which prevents further integration. Also due to this filter, large feedback factors are hard to realise, so that the load influences the distortion- and transfer
Tuijl, A.J.M. van, Zee, R.A.R. van der
core   +2 more sources

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