By dawn or dusk—how circadian timing rewrites bacterial infection outcomes
The circadian clock shapes immune function, yet its influence on infection outcomes is only beginning to be understood. This review highlights how circadian timing alters host responses to the bacterial pathogens Salmonella enterica, Listeria monocytogenes, and Streptococcus pneumoniae revealing that the effectiveness of immune defense depends not only
Devons Mo +2 more
wiley +1 more source
Design of SiC-Si Hybrid Interleaved 3-Phase 5-Level E-Type Back-to-Back Converter
In modern applications, such as variable frequency electric drives, aircraft propulsion, electric vehicles, and uninterruptible power supply units, high power-dense, and efficient AC-AC power converters are the key to reducing power losses, thus limiting
Marco di Benedetto +2 more
doaj +1 more source
Analog-to-digital converter has increased reliability and reduced power consumption [PDF]
Eight-bit analog-to-digital converter decreases average power consumption and increases component reliability. The converter uses solid-state components in pulse operation and magnetic core components for minimizing power consumption.
Thornwall, J. C.
core +1 more source
Hematopoietic (stem) cells—The elixir of life?
The aging of HSCs (hematopoietic stem cells) and the blood system leads to the decline of other organs. Rejuvenating aged HSCs improves the function of the blood system, slowing the aging of the heart, kidney, brain, and liver, and the occurrence of age‐related diseases.
Emilie L. Cerezo +4 more
wiley +1 more source
Analysis of an LLC–DAB integrated DC–DC converter topology with low loss and low cost
This paper proposes an LLC‐DAB integrated high‐frequency isolated DC–DC converter topology structure to reduce the loss and cost of the DC power distribution system. Furthermore, the complexity and efficiency of the system also can be improved.
Shichong Zhang +3 more
doaj +1 more source
Generic closed loop controller for power regulation in dual active bridge DC-DC converter with current stress minimization [PDF]
This paper presents a comprehensive and generalized analysis of the bidirectional dual active bridge (DAB) DC/DC converter using triple phase shift (TPS) control to enable closed loop power regulation while minimizing current stress.
Abdelsalam, Ibrahim +3 more
core +3 more sources
This perspective highlights emerging insights into how the circadian transcription factor CLOCK:BMAL1 regulates chromatin architecture, cooperates with other transcription factors, and coordinates enhancer dynamics. We propose an updated framework for how circadian transcription factors operate within dynamic and multifactorial chromatin landscapes ...
Xinyu Y. Nie, Jerome S. Menet
wiley +1 more source
Real‐time assay of ribonucleotide reductase activity with a fluorescent RNA aptamer
Ribonucleotide reductases (RNR) synthesize DNA building blocks de novo, making them crucial in DNA replication and drug targeting. FLARE introduces the first single‐tube real‐time coupled RNR assay, which enables isothermal tracking of RNR activity at nanomolar enzyme levels and allows the reconstruction of allosteric regulatory patterns and rapid ...
Jacopo De Capitani +4 more
wiley +1 more source
AC-DC PFC Converter Using Combination of Flyback Converter and Full-bridge DC-DC Converter
This paper presents a combination of power factor correction converter using Flyback converter and Full-bridge dc-dc converter in series connection. Flyback converter is operated in discontinuous conduction mode so that it can serve as a power factor ...
Moh. Zaenal Efendi +4 more
doaj +3 more sources
Demonstration of sustained and useful converter responses during balanced and unbalanced faults in microgrids [PDF]
In large power grids where converter penetration is presently low and the network impedance is predominantly reactive, the required response from converters during faults is presently specified by phrases such as “maximum reactive output”.
Burt, Graeme +4 more
core +1 more source

