Results 71 to 80 of about 5,414 (165)

Mapuera virus, a rubulavirus that inhibits interferon signalling in a wide variety of mammalian cells without degrading STATs

, 2007
Majouera virus (MPRV) is a paramyxovirus that was originally isolated from bats, but its host range remains unknown. It was classified as a member of the genus Rubulavirus on the basis of structural and genetic features.
Goodbourn, S, Childs, K, Randall, RE, Precious, B, Stock, N, Wang, LF, Hagmaier, K, Randall, Richard Edward, Wang, L-F   +8 more
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NK Cells and Poxvirus infection

Frontiers in Immunology, 2013
In recent years our understanding of the role of NK cells in the response to viral infection has grown rapidly. Not only do we realize viruses have many immune evasion strategies to escape NK cell responses, but that stimulation of NK cell subsets ...
Deborah N. Burshtyn
doaj   +1 more source

Evaluation and Clinical Validation of Pan‐Specific and Clade‐Specific Diagnostic Real‐Time PCR Assays for Monkeypox Virus

Journal of Medical Virology, Volume 98, Issue 4, April 2026.
ABSTRACT Human mpox, formerly known as monkeypox, has twice been declared a Public Health Emergency of International Concern (PHEIC) by the World Health Organization, in 2022 and 2024. Despite this, global access to rapid, reliable diagnostics remains limited, hindering outbreak control and equitable clinical response. To address this gap, we developed
Hong Chang, Tin Hang Hung, Binbin Li, Bobby Lim‐Ho Kong, Ashwathi Asha Madhaven, Yue Wang, Ming‐shan Tsai, Dan Deng, Zhanfeng Cui   +8 more
wiley   +1 more source

Ocular Vaccinia Infection in Laboratory Worker, Philadelphia, 2004

Emerging Infectious Diseases, 2006
We report a case of ocular vaccinia infection in an unvaccinated laboratory worker. The patient was infected by a unique strain used in an experiment performed partly outside a biosafety cabinet.
Felicia M.T. Lewis, Esther Chernak, Erinn Goldman, Yu Li, Kevin Karem, Inger K. Damon, Richard Henkel, E. Claire Newbern, Patrina Ross, Caroline C. Johnson   +9 more
doaj   +1 more source

Human Cyclophilins—An Emerging Class of Drug Targets

Medicinal Research Reviews, Volume 46, Issue 2, Page 475-512, March 2026.
ABSTRACT Cyclophilins are a family of enzymes with peptidyl‐prolyl isomerase activity found in all cells of all organisms. To date, 17 cyclophilin isoforms have been identified in the human body, participating in diverse biological processes. Consequently, cyclophilins have emerged as promising targets for drug development to address a wide array of ...
Katarina Jurkova, Hana Navratilova, Kamil Musilek, Ondrej Benek   +3 more
wiley   +1 more source

Methods of treating Poxviral Infections

, 2011
The present application relates to iminosugars and methods of treating viral infections with iminosugars and, in particular, to the use of iminosugars for treatment and/or prevention of viral infections caused by or associated with a virus belonging to ...
Klose, Brennan, Butters, Terry D, Zitzmann, N, Dwek, Raymond A, Klose, B, Butters, T, Ramstedt, U, Dwek, R, Zitzmann, Nicole, Ramstedt, Urban   +9 more
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Vaccinia virus modulates the redox environment by inhibiting reactive oxygen and nitrogen species with increased activity of endogenous antioxidant enzymes

Scientific Reports
The vaccinia virus (VACV) is the most studied and well-characterised member of the Poxviridae family. However, the mechanisms through which it modulates redox homeostasis in host cells remain unclear.
Marília Bueno da Silva Menegatto, Ariane Coelho Ferraz, Rafaela Lameira Souza Lima, Pedro Henrique Guimarães, Oluwashola Samuel Ola-Olu, Pedro Alves Machado-Junior, Wellington Carvalho Malta, Thaís de Fátima Silva Moraes, Frank Silva Bezerra, Breno de Mello Silva, José Carlos de Magalhães, Jordana Grazziela Alves Coelho dos Reis, Flávio Guimarães da Fonseca, Giliane de Souza Trindade, Erna Geessien Kroon, Cintia Lopes de Brito Magalhães   +15 more
doaj   +1 more source

Poxvirus & Rabies Branch (PRB) [PDF]

The epidemiologists, laboratory scientists, and public health professionals in PRB are responsible for surveillance, control, and prevention of illness and death due to poxviruses and rabies.CS256610Publication date from document properties.pox-rabies ...

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Monkey pox [PDF]

Hospital Pharmacology
Introduction: The endemic monkeypox virus (MPXV) is a double-stranded DNA virus that is a member of the Orthopoxviral genus of the Poxviridae family. The viruses proliferate quickly and enter the bloodstream, where they cause viremia, which subsequently ...
Hoque Majedul M.
doaj   +1 more source

The development of penguinpox virus (PEPV) as a vaccine vector : transfer vector construction and rescue of virus growth in rabbit kidney cells (RK-13) by vaccinia virus K1

, 2010
Includes bibliographical references (leaves 131-137).Of the many vaccine trials which have taken place, the most promising results have been obtained from the recent phase 3 clinical trial which tested the ability of a dual protein and Canarypox virus ...
Hu, Nai-Chung
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