TCEPVDB: Artificial Intelligence-Based Proteome-Wide Screening of Antigens and Linear T-Cell Epitopes in the Poxviruses and the Development of a Repository [PDF]
ProteomesBackground: Poxviruses constitute a family of large dsDNA viruses that can infect a plethora of species including humans. Historically, poxviruses have caused a health burden in multiple outbreaks.
David J Kelvin +2 more
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Emerging interplays between poxviruses and autophagy [PDF]
Frontiers in Cellular and Infection MicrobiologyPoxviruses are large double-stranded DNA viruses that replicate exclusively in the cytoplasm. Their life cycle is closely associated with various membrane-related cellular processes.
Yongge Li +4 more
doaj +4 more sources
Comparative Genomic Analysis of Two Bat Poxviruses in the Genus Vespertilionpoxvirus [PDF]
VirusesPoxviruses are large double-stranded DNA (dsDNA) viruses that cause important human and animal diseases, including smallpox and mpox. Poxviruses have also been identified in diverse bat populations; however, their potential for zoonotic transmission and ...
Chi Zhang +4 more
doaj +3 more sources
Poxviruses in Bats … so What? [PDF]
Viruses, 2014 Poxviruses are important pathogens of man and numerous domestic and wild animal species. Cross species (including zoonotic) poxvirus infections can have drastic consequences for the recipient host.
Kate Baker, Pablo R Murcia
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Battle Royale: Innate Recognition of Poxviruses and Viral Immune Evasion [PDF]
Biomedicines, 2021 Host pattern recognition receptors (PRRs) sense pathogen-associated molecular patterns (PAMPs), which are molecular signatures shared by different pathogens.
Stefan Rothenburg +2 more
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A Selectable and Excisable Marker System for the Rapid Creation of Recombinant Poxviruses [PDF]
PLoS ONE, 2011 Genetic manipulation of poxvirus genomes through attenuation, or insertion of therapeutic genes has led to a number of vector candidates for the treatment of a variety of human diseases.
John Bell, Jiahu Wang
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Frontiers in Microbiology, 2023 The monkeypox virus (MPXV) has become a major threat due to the increasing global caseload and the ongoing multi-country outbreak in non-endemic territories.
Jatin Chadha
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Journal of Infection and Public HealthBackground: Poxviruses comprise a group of large double-stranded DNA viruses and are known to cause diseases in humans, livestock animals, and other animal species. The Mpox virus (MPXV; formerly Monkeypox), variola virus (VARV), and volepox virus (VPXV)
David J Kelvin, Mansi Dutt, Anuj Kumar
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Rapid spread of MPXV clade Ib with high genetic relatedness among men who have sex with men, Berlin, Germany, week 50 2025 up to week 10 2026 [PDF]
EurosurveillanceFollowing the first detection of monkeypox virus (MPXV) clade Ib in Berlin, Germany, in December 2025, clade Ib rapidly predominated over clade IIb among notified mpox cases.
Janine Michel
doaj +2 more sources
Poxvirus A52 protein subverts autophagy flux by blocking autophagosome-lysosome fusion to promote viral replication. [PDF]
PLoS PathogensMany poxviruses are significant zoonotic pathogens threatening public health. Autophagy, a regulated process vital for cellular homeostasis, can participate in defense against virus invasion.
Kang Niu +9 more
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