Results 21 to 30 of about 10,498 (172)
Annual Review of Virology, 2014 Current standard treatments of cancer can prolong survival of many cancer patients but usually do not effectively cure the disease. Oncolytic virotherapy is an emerging therapeutic for the treatment of cancer that exploits replication-competent viruses to selectively infect and destroy cancerous cells while sparing normal cells and tissues.
Winnie M, Chan, Grant, McFadden
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Cell Host & Microbe, 2007 Successful viruses engage in a dynamic interplay with their hosts, where both utilize diverse strategies to impose their supremacy. In this issue of Cell Host & Microbe, Wiebe and Traktman describe a novel interaction between vaccinia virus and mammalian cells.
Department of Molecular Genetics and Microbiology, College of Medicine, University of Florida Southwest Archer Road, P.O. Box 100332, Gainesville, FL 32610, USA ( host institution ) +2 more
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Cowpox Viruses: A Zoo Full of Viral Diversity and Lurking Threats
Biomolecules, 2023 Cowpox viruses (CPXVs) exhibit the broadest known host range among the Poxviridae family and have caused lethal outbreaks in various zoo animals and pets across 12 Eurasian countries, as well as an increasing number of human cases.
Ryan C. Bruneau +2 more
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Viruses, 2022 Cetacean poxviruses (CePVs) cause ‘tattoo’ skin lesions in small and large cetaceans worldwide. Although the disease has been known for decades, genomic data for these poxviruses are very limited, with the exception of CePV-Tursiops aduncus, which was ...
Léa Luciani +4 more
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Monkeypox and other zoonotic poxviruses
, 2022 Poxviruses have caused the most important diseases for humanity for a long time. An important triumph was achieved with the eradication of smallpox, defined by the World Health Organization in 1979.
Ahmet Kürşat AZKUR +5 more
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Vaccines, 2023 Background: The years 2022–2023 witnessed a monkeypox virus (mpox) outbreak in some countries worldwide, where it exists in an endemic form. However, the number of infectious cases is continuously on the rise, and there has been an unexpected, drastic ...
Shiza Malik +4 more
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Poxvirus Interactions with the Host Ubiquitin System
Pathogens, 2021 The ubiquitin system has emerged as a master regulator of many, if not all, cellular functions. With its large repertoire of conjugating and ligating enzymes, the ubiquitin system holds a unique mechanism to provide selectivity and specificity in ...
Sian Lant, Carlos Maluquer de Motes
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Veterinary Microbiology, 2010 (Uploaded by Plazi for the Bat Literature Project) Poxviruses compromise a group of long known important pathogens including some zoonotic members affecting lifestock animals and humans. While whole genome sequence analysis started to shed light into the molecular mechanisms underlying host cell infection, viral replication as well as virulence, our ...
Essbauer, Sandra +2 more
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Journal of Medical Science, 2022 Human monkeypox represents a relatively underexplored infection that has received increased attention since the reported outbreak in May 2022. Due to its clinical similarities with human smallpox, this virus represents a potentially tremendous health ...
Dženan Kovačić, Adna Salihović
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Molecular Mechanisms of Poxvirus Evolution
mBio, 2023 Poxviruses are often thought to evolve relatively slowly because they are double-stranded DNA pathogens with proofreading polymerases. However, poxviruses have highly adaptable genomes and can undergo relatively rapid genotypic and phenotypic change, as ...
Greg Brennan +8 more
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