Results 1 to 10 of about 15,703 (207)

Genomic Analysis of Novel Poxvirus Brazilian Porcupinepox Virus, Brazil, 2019

Emerging Infectious Diseases, 2021
We obtained the complete sequence of a novel poxvirus, tentatively named Brazilian porcupinepox virus, from a wild porcupine (Coendou prehensilis) in Brazil that had skin and internal lesions characteristic of poxvirus infection.
Aline S. Hora, Sueli A. Taniwaki, Nathana B. Martins, Nataly N.R. Pinto, André E. Schlemper, André L.Q. Santos, Matias P.J. Szabó, Paulo E. Brandão   +7 more
doaj   +2 more sources

Temporal expression classes and functions of vaccinia virus and mpox (monkeypox) virus genes [PDF]

mBio
Poxviruses comprise pathogens that are highly pathogenic to humans and animals, causing diseases such as smallpox and mpox (formerly monkeypox). The family also contains members developed as vaccine vectors and oncolytic agents to fight other diseases ...
Yining Deng, Santiago Navarro-Forero, Zhilong Yang   +2 more
doaj   +2 more sources

Pharmacokinetics and Efficacy of a Potential Smallpox Therapeutic, Brincidofovir, in a Lethal Monkeypox Virus Animal Model

mSphere, 2021
Preparedness activities against highly transmissible viruses with high mortality rates have been highlighted during the ongoing coronavirus disease 2019 (COVID-19) pandemic.
Christina L. Hutson, Ashley V. Kondas, Mathew R. Mauldin, Jeffrey B. Doty, Irma M. Grossi, Clint N. Morgan, Sharon Dietz Ostergaard, Christine M. Hughes, Yoshinori Nakazawa, Chantal Kling, Brock E. Martin, James A. Ellison, Darin D. Carroll, Nadia F. Gallardo-Romero, Victoria A. Olson   +14 more
doaj   +1 more source

Rabies experts on demand: A cross‐sectional study describing the use of a rabies telehealth service

Public Health Challenges, 2023
Background Rabies expert on demand (REOD) telehealth service is provided by the U.S. Centers for Disease Control and Prevention (CDC) to assist public health practitioners, health providers, and the public to interpret national and international rabies ...
Sarah E. Baker, Yasmeen B. Ross, James A. Ellison, Benjamin P. Monroe, Lillian A. Orciari, Brett W. Petersen, Agam K. Rao, Ryan M. Wallace   +7 more
doaj   +1 more source

A cocktail of human monoclonal antibodies broadly neutralizes North American rabies virus variants as a promising candidate for rabies post-exposure prophylaxis

Scientific Reports, 2022
Human rabies remains a globally significant public health problem. Replacement of polyclonal anti-rabies immunoglobulin (RIG), a passive component of rabies post-exposure prophylaxis (PEP), with a monoclonal antibody (MAb), would eliminate the cost and ...
Monir Ejemel, Todd G. Smith, Lauren Greenberg, William C. Carson, David Lowe, Yong Yang, Felix R. Jackson, Clint N. Morgan, Brock E. Martin, Chantal Kling, Christina L. Hutson, Nadia Gallardo-Romero, James A. Ellison, Susan Moore, Adam Buzby, John Sullivan-Bolyai, Mark Klempner, Yang Wang   +17 more
doaj   +1 more source

Revealing the complexity of vampire bat rabies “spillover transmission”

Infectious Diseases of Poverty, 2023
Background The term virus ‘spillover’ embodies a highly complex phenomenon and is often used to refer to viral transmission from a primary reservoir host to a new, naïve yet susceptible and permissive host species.
Luis E. Escobar, Andres Velasco-Villa, Panayampalli S. Satheshkumar, Yoshinori Nakazawa, Paige Van de Vuurst   +4 more
doaj   +1 more source

Analysis of available animal testing data to propose peer-derived quantitative thresholds for determining adequate surveillance capacity for rabies

Scientific Reports, 2023
Historical targets for country-level animal rabies testing volumes were abandoned due to ethical and welfare concerns, and interpretation challenges of testing healthy animals.
Faisal S. Minhaj, Sarah C. Bonaparte, Cassandra Boutelle, Ryan M. Wallace   +3 more
doaj   +1 more source

Identification of Novel Cetacean Poxviruses in Cetaceans Stranded in South West England. [PDF]

PLoS ONE, 2015
Poxvirus infections in marine mammals have been mainly reported through their clinical lesions and electron microscopy (EM). Poxvirus particles in association with such lesions have been demonstrated by EM and were previously classified as two new ...
James Barnett, Akbar Dastjerdi, Nick Davison, Rob Deaville, David Everest, Julie Peake, Christopher Finnegan, Paul Jepson, Falko Steinbach   +8 more
doaj   +1 more source

Detection of Novel Poxvirus from Gray Seal (Halichoerus grypus), Germany

Emerging Infectious Diseases, 2023
We detected a novel poxvirus from a gray seal (Halichoerus grypus) from the North Sea, Germany. The juvenile animal showed pox-like lesions and deteriorating overall health condition and was finally euthanized. Histology, electron microscopy, sequencing,
Florian Pfaff, Katharina Kramer, Jacqueline King, Kati Franzke, Tanja Rosenberger, Dirk Höper, Patricia König, Donata Hoffmann, Martin Beer   +8 more
doaj   +1 more source

Progress on Poxvirus E3 Ubiquitin Ligases and Adaptor Proteins

Frontiers in Immunology, 2021
Poxviruses have evolved a variety of innate immunity evasion mechanisms, some of which involve poxvirus-encoded E3 ubiquitin ligases and adaptor proteins.
Haoran Cui, Haoran Cui, Haoran Cui, Yaxian Zhang, Yaxian Zhang, Leiliang Zhang, Leiliang Zhang, Leiliang Zhang   +7 more
doaj   +1 more source