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A Phylogeographic Investigation of African Monkeypox
Viruses, 2015 Monkeypox is a zoonotic disease caused by a virus member of the genus Orthopoxvirus and is endemic to Central and Western African countries. Previous work has identified two geographically disjuct clades of monkeypox virus based on the analysis of a few ...
Yoshinori Nakazawa +14 more
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Viruses, 2017 Monkeypox is a smallpox-like illness that can be accompanied by a range of significant medical complications. To date there are no standard or optimized guidelines for the clinical management of monkeypox (MPX) patients, particularly in low-resource ...
Mary G. Reynolds +4 more
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Molecular Mechanisms of Poxvirus Evolution [PDF]
mBio, 2023 Poxviruses are often thought to evolve relatively slowly because they are double-stranded DNA pathogens with proofreading polymerases. However, poxviruses have highly adaptable genomes and can undergo relatively rapid genotypic and phenotypic change, as illustrated by the recent increase in human-to-human transmission of monkeypox virus.
Greg Brennan +8 more
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F1000Research, 2013 We analyzed how land-use patterns and changes in urbanization influence reported rabid raccoons in Georgia from 2006 - 2010. Using Geographical Information Systems and rabies surveillance data, multivariate analysis was conducted on 15 land-use ...
John E. Duke +3 more
doaj +1 more source
A Poxvirus in a Marsupial Papilloma
Journal of General Virology, 1972 We wish to present some evidence for the implication of an as yet uncharacterized member of the pox group of viruses in producing epidermal papillomata in a marsupial, Setonix brachyurus. Generally neoplasms in marsupials have not been investigated in any great detail (Barker, Calaby & Sharman, 1963), and it is interesting that in the population of S ...
Papadimitriou, J. M., Ashman, R. B.
openaire +4 more sources
F1000Research, 2014 We analyzed how land-use patterns and changes in urbanization influence reported rabid raccoons in Georgia from 2006 - 2010. Using Geographical Information Systems and rabies surveillance data, multivariate analysis was conducted on 15 land-use ...
John E. Duke +3 more
doaj +1 more source
The 5'-poly(A) leader of poxvirus mRNA confers a translational advantage that can be achieved in cells with impaired cap-dependent translation. [PDF]
PLoS Pathogens, 2017 The poly(A) leader at the 5'-untranslated region (5'-UTR) is an unusually striking feature of all poxvirus mRNAs transcribed after viral DNA replication (post-replicative mRNAs).
Pragyesh Dhungel +2 more
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Proceedings of the National Academy of Sciences, 2007 Poxviruses are large enveloped viruses that replicate in the cytoplasm of vertebrate or invertebrate cells. At least six virus-encoded proteins are required for synthesis and processing of the double-stranded DNA genome of vaccinia virus, the prototype member of the family.
Frank S, De Silva +4 more
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Laboratory Infection of Novel Akhmeta Virus in CAST/EiJ Mice
Viruses, 2020 Akhmeta virus is a zoonotic Orthopoxvirus first identified in 2013 in the country of Georgia. Subsequent ecological investigations in Georgia have found evidence that this virus is widespread in its geographic distribution within the country and in its ...
Clint N. Morgan +10 more
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Antiviral Ranpirnase TMR-001 Inhibits Rabies Virus Release and Cell-to-Cell Infection In Vitro
Viruses, 2020 Currently, no rabies virus-specific antiviral drugs are available. Ranpirnase has strong antitumor and antiviral properties associated with its ribonuclease activity.
Todd G. Smith +12 more
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