Results 11 to 20 of about 12,825 (182)

Poxvirus Recombination

Pathogens, 2022
Genetic recombination is used as a tool for modifying the composition of poxvirus genomes in both discovery and applied research. This review documents the history behind the development of these tools as well as what has been learned about the processes
David Hugh Evans
doaj   +3 more sources

Protective Human Anti-Poxvirus Monoclonal Antibodies Are Generated from Rare Memory B Cells Isolated by Multicolor Antigen Tetramers

Vaccines, 2022
Smallpox, an epidemic disease caused by Orthopoxvirus variola, was eradicated worldwide through immunization. The immunization against smallpox was discontinued in 1980.
Xiuling Gu, Yufan Zhang, Wei Jiang, Dongfang Wang, Jiao Lu, Guanglei Gu, Chengfeng Qin, Min Fang   +7 more
doaj   +1 more source

Progress on Poxvirus E3 Ubiquitin Ligases and Adaptor Proteins

Frontiers in Immunology, 2021
Poxviruses have evolved a variety of innate immunity evasion mechanisms, some of which involve poxvirus-encoded E3 ubiquitin ligases and adaptor proteins.
Haoran Cui, Haoran Cui, Haoran Cui, Yaxian Zhang, Yaxian Zhang, Leiliang Zhang, Leiliang Zhang, Leiliang Zhang   +7 more
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Israeli Rousettus aegyptiacus Pox Virus (IsrRAPXV) Infection in Juvenile Egyptian Fruit Bat (Rousettus aegyptiacus): Clinical Findings and Molecular Detection

Viruses, 2021
During 2019, five carcasses of juvenile Egyptian fruit bats (Rousettus aegyptiacus) were submitted to the Kimron Veterinary Institute. These bats exhibited typical poxvirus like lesion plaques of different sizes on the skin, abdomen and the ventral side ...
Dan David, Irit Davidson, Sharon Karniely, Nir Edery, Ariela Rosenzweig, Asaf Sol   +5 more
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Inactivated Rabies Virus-Vectored Immunocontraceptive Vaccine in a Thermo-Responsive Hydrogel Induces High and Persistent Antibodies against Rabies, but Insufficient Antibodies against Gonadotropin-Releasing Hormone for Contraception

Vaccines, 2019
Rabies is preventable through vaccination, but the need to mount annual canine vaccination campaigns presents major challenges in rabies control and prevention.
Xianfu Wu, Yong Yang, Chantal Kling, Laurie Seigler, Nadia F. Gallardo-Romero, Brock E. Martin, Todd G. Smith, Victoria A. Olson   +7 more
doaj   +1 more source

IMVAMUNE^® and ACAM2000^® Provide Different Protection against Disease When Administered Postexposure in an Intranasal Monkeypox Challenge Prairie Dog Model

Vaccines, 2020
The protection provided by smallpox vaccines when used after exposure to Orthopoxviruses is poorly understood. Postexposu re administration of 1st generation smallpox vaccines was effective during eradication.
M. Shannon Keckler, Johanna S Salzer, Nishi Patel, Michael B Townsend, Yoshinori J Nakazawa, Jeffrey B Doty, Nadia F Gallardo-Romero, Panayampalli S Satheshkumar, Darin S Carroll, Kevin L Karem, Inger K Damon   +10 more
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T helper 1 effector memory CD4+ T cells protect the skin from poxvirus infection

Cell Reports, 2023
Summary: Poxvirus infections of the skin are a recent emerging public health concern, yet the mechanisms that mediate protective immunity against these viral infections remain largely unknown.
Jake C. Harbour, Mahmoud Abdelbary, John B. Schell, Samantha P. Fancher, Jack J. McLean, Taylen J. Nappi, Susan Liu, Timothy J. Nice, Zheng Xia, Klaus Früh, Jeffrey C. Nolz   +10 more
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The Genome of Yoka Poxvirus [PDF]

Journal of Virology, 2011
ABSTRACT Yoka poxvirus was isolated almost four decades ago from a mosquito pool in the Central African Republic. Its classification as a poxvirus is based solely upon the morphology of virions visualized by electron microscopy. Here we describe sequencing of the Yoka poxvirus genome using a combination of Roche/454 and Illumina ...
Guoyan, Zhao, Lindsay, Droit, Robert B, Tesh, Vsevolod L, Popov, Nicole S, Little, Chris, Upton, Herbert W, Virgin, David, Wang   +7 more
openaire   +2 more sources

Poxvirus pathogenesis

Microbiological Reviews, 1991
Poxviruses are a highly successful family of pathogens, with variola virus, the causative agent of smallpox, being the most notable member. Poxviruses are unique among animal viruses in several respects. First, owing to the cytoplasmic site of virus replication, the virus encodes many enzymes required either for macromolecular precursor pool regulation
R M, Buller, G J, Palumbo
openaire   +2 more sources

Emergence of a Novel Pathogenic Poxvirus Infection in the Endangered Green Sea Turtle (Chelonia mydas) Highlights a Key Threatening Process

Viruses, 2021
Emerging viral disease is a significant concern, with potential consequences for human, animal and environmental health. Over the past several decades, multiple novel viruses have been found in wildlife species, including reptiles, and often pose a major
Subir Sarker, Christabel Hannon, Ajani Athukorala, Helle Bielefeldt-Ohmann   +3 more
doaj   +1 more source