Results 41 to 50 of about 24,392 (225)
The poxvirus F17 protein counteracts mitochondrially orchestrated antiviral responses
Nature Communications, 2023 Poxviruses are unusual DNA viruses that replicate in the cytoplasm. To do so, they encode approximately 100 immunomodulatory proteins that counteract cytosolic nucleic acid sensors such as cGAMP synthase (cGAS) along with several other antiviral response
Nathan Meade +6 more
doaj +1 more source
PLoS Pathogens, 2022 The evolutionarily successful poxviruses possess effective and diverse strategies to circumvent or overcome host defense mechanisms. Poxviruses encode many immunoregulatory proteins to evade host immunity to establish a productive infection and have ...
Steven J Conrad +7 more
doaj +1 more source
Poxvirus under the eyes of electron microscope
Applied Microscopy, 2022 Zoonotic poxvirus infections pose significant threat to human health as we have witnessed recent spread of monkeypox. Therefore, insights into molecular mechanism behind poxvirus replication cycle are needed for the development of efficient antiviral ...
Jaekyung Hyun
doaj +1 more source
Poxvirus DNA Replication [PDF]
Cold Spring Harbor Perspectives in Biology, 2013 Poxviruses are large, enveloped viruses that replicate in the cytoplasm and encode proteins for DNA replication and gene expression. Hairpin ends link the two strands of the linear, double-stranded DNA genome. Viral proteins involved in DNA synthesis include a 117-kDa polymerase, a helicase-primase, a uracil DNA glycosylase, a processivity factor, a ...
openaire +2 more sources
A broadly applicable method to characterize large DNA viruses and adenoviruses based on the DNA polymerase gene [PDF]
, 2006 Background Many viral pathogens are poorly characterized, are difficult to culture or reagents are lacking for confirmatory diagnoses. We have developed and tested a robust assay for detecting and characterizing large DNA viruses and adenoviruses.
Larry A Hanson +3 more
core +1 more source
Vaccines, 2020 Four decades after the eradication of smallpox, poxviruses continue to threaten the health of humans and other animals. Vaccinia virus (VACV) was used as the vaccine that successfully eradicated smallpox and is a prototypic member of the poxvirus family.
Chen Peng +7 more
doaj +1 more source
Strategies and Patterns of Codon Bias in Molluscum Contagiosum Virus
Pathogens, 2021 Trends associated with codon usage in molluscum contagiosum virus (MCV) and factors governing the evolution of codon usage have not been investigated so far.
Rahul Raveendran Nair +4 more
doaj +1 more source
Contemporary outbreaks of different avipoxviruses in Humboldt penguins of wild animal park Planckendael and in chickens of commercial poultry farms in Belgium [PDF]
, 2017 In the present study, the first outbreak of a penguinpox virus (PPV) in Humboldt penguins (Spheniscus humboldd) and four outbreaks of fowlpox virus (FPV) in layer chickens are reported.
Avalakuppa Papi Reddy, Vishwanatha Reddy +3 more
core
Biotechnology and Bioengineering, EarlyView.ABSTRACT The detergent Triton X‐100 (TX‐100) is a typical component of solvent/detergent (S/D) mixes applied for virus inactivation steps of biomanufacturing processes, yet environmentally unfavorable properties have led to restrictions on its use. Deviron 13‐S9 has recently been described as an eco‐friendly TX‐100 alternative, with powerful virus ...
Johanna Kindermann +3 more
wiley +1 more source
Frontiers in Veterinary Science, 2023 Fifty-five skin lesions from 31 stranded cetaceans along the Canary coasts (2011–2021) were submitted to macroscopic, histological, and molecular analyses to confirm infection by cetacean poxvirus, herpesvirus and cetacean morbillivirus.
Simone Segura-Göthlin +7 more
doaj +1 more source