Results 51 to 60 of about 16,696 (211)

Viral skin diseases in odontocete cetaceans: gross, histopathological, and molecular characterization of selected pathogens

open access: yesFrontiers in Veterinary Science, 2023
Fifty-five skin lesions from 31 stranded cetaceans along the Canary coasts (2011–2021) were submitted to macroscopic, histological, and molecular analyses to confirm infection by cetacean poxvirus, herpesvirus and cetacean morbillivirus.
Simone Segura-Göthlin   +7 more
doaj   +1 more source

Status and future of recombinant adeno‐associated virus vector manufacturing

open access: yesBiotechnology Progress, EarlyView.
Abstract Sixty years of adeno‐associated virus (AAV) research illustrates a trajectory marked by basic science exploration, iterative innovation, persistent challenges, a number of clinical setbacks, as well as commercial therapeutic triumphs. This continual evolution has led to recombinant AAV (rAAV) becoming a cornerstone of modern gene therapy ...
Frank Agbogbo, David Dismuke
wiley   +1 more source

What is rural? Examining the relationship between human populations and their inter-connectedness in the context of communicable disease transmission

open access: yesInternational Journal of Health Geographics
Background Rurality and urbanicity are recognized determinants of public health outcomes that influence policy and resource allocation. However, many commonly used methods to classify the rural-urban continuum, such as the Rural-Urban Commuting Area ...
Cassandra Boutelle   +6 more
doaj   +1 more source

Cowpox virus: What’s in a Name?

open access: yesViruses, 2017
Traditionally, virus taxonomy relied on phenotypic properties; however, a sequence-based virus taxonomy has become essential since the recent requirement of a species to exhibit monophyly.
Matthew R. Mauldin   +6 more
doaj   +1 more source

Strategies and Patterns of Codon Bias in Molluscum Contagiosum Virus

open access: yesPathogens, 2021
Trends associated with codon usage in molluscum contagiosum virus (MCV) and factors governing the evolution of codon usage have not been investigated so far.
Rahul Raveendran Nair   +4 more
doaj   +1 more source

Pietro Verri: The History of Smallpox Vaccination Through His Pencil

open access: yesJEADV Clinical Practice, EarlyView.
ABSTRACT The last case of natural smallpox infection occurred in 1977, and the disease is considered eradicated since 1980. Throughout the history of medicine, early attempts to combat smallpox involved inoculation, a practice based on the observation that those who recovered from the disease became immune.
Omar Simonetti   +5 more
wiley   +1 more source

Zoonotic Poxviruses Associated with Companion Animals

open access: yesAnimals, 2011
Understanding the zoonotic risk posed by poxviruses in companion animals is important for protecting both human and animal health. The outbreak of monkeypox in the United States, as well as current reports of cowpox in Europe, point to the fact that ...
Mary G. Reynolds, Danielle M. Tack
doaj   +1 more source

Early Mpox Detection: Integrating Skin Lesion Imaging, Epidemiology, and Treatment for Deep Learning Approaches

open access: yesMedicine Advances, EarlyView.
Research papers utilizing publicly available, web‐scraped resources related to mpox—including news portals and datasets such as Monkeypox2022, Kaggle, and the Monkeypox Skin Images Dataset—demonstrate variability in accuracy. Our findings suggest that although deep learning models such as MobileNetV2, VGG16, and GoogLeNet report accuracy exceeding 95%,
Taskin Sabit, Faiza Tasnim
wiley   +1 more source

Vaccinia virus replication is not affected by APOBEC3 family members [PDF]

open access: yes, 2006
Background: The APOBEC3G protein represents a novel innate defense mechanism against retroviral infection. It facilitates the deamination of the cytosine residues in the single stranded cDNA intermediate during early steps of retroviral infection.
Sutter Gerd   +17 more
core   +1 more source

Exploring the Development of Vaccine Platforms, With a Particular Focus on the COVID‐19 Pandemic

open access: yesActa Paediatrica, EarlyView.
ABSTRACT Vaccines have been a cornerstone of human health for more than 200 years and one of the most important tools to reduce childhood deaths caused by pathogens. The concept of vaccines is basically to take something safe, make it immunogenic and induce an immune response in the host that will protect it against something dangerous. Live attenuated
Matti Sällberg
wiley   +1 more source

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