Results 61 to 70 of about 16,870 (170)

The Role of Viruses in the Pathogenesis of Periodontitis

Journal of Periodontal Research, EarlyView.
This narrative review aimed to summarize current evidence on the presence and potential pathogenic role of viruses in periodontitis. Design: Narrative Review; Population: Patients with periodontitis; Exposure: Detection of viruses in oral samples (biopsies, saliva, gingival crevicular fluid, subgingival plaque, blood); Outcome: Viral prevalence, load ...
Kim Natalie Stolte, Jørgen Slots, Henrik Dommisch   +2 more
wiley   +1 more source

Use of poxvirus display to select antibodies specific for complex membrane antigens

, 2023
Antibody discovery against complex antigens is limited by the availability of a reproducible pure source of concentrated properly folded antigen. We have developed a technology to enable direct incorporation of membrane proteins such as GPCRs and into ...
Jessica M. Mayer, Ernest S. Smith, Alan P. Howell, Elizabeth E. Evans, Renee A. Kirk, Loretta L. Mueller, Madeleine R. Keefe, Leslie A. Balch, Angelica A. Cornelison, Malgorzata Gil-Moore, Maria Scrivens, Shuying Shi, Caroline D. Harvey, Christine A. Reilly, Mark J. Paris, Elaine M. Gersz, Maurice Zauderer, Wei Wang, Kari A Viggiani, Francis G. Murante, Richard L. Hall, Holm Bussler   +21 more
core   +1 more source

An integrated workflow for Mycoplasma detection and removal from cell cultures and viral stocks

Current Protocols, Volume 6, Issue 11, November 2026.
Abstract Contamination of cell cultures and viral stocks with Mycoplasma is one of the most frequent and underdiagnosed problems in laboratories working with these materials, severely affecting experimental reproducibility, data reliability, and biosafety.
Eliza Flores‐Souza, Carolina Colombelli Pacca‐Mazaro, Naiara Clemente Tavares, Camila Salles Nascimento, Tamiris Vanessa Miguel de Souza, Anna Beatriz de Oliveira Mendes, Erna Geessien Kroon, Carlos Eduardo Calzavara‐Silva, Jaquelline Germano de Oliveira   +8 more
wiley   +1 more source

Exploring the Development of Vaccine Platforms, With a Particular Focus on the COVID‐19 Pandemic

Acta Paediatrica, Volume 115, Issue 11, Page 2421-2426, November 2026.
ABSTRACT Vaccines have been a cornerstone of human health for more than 200 years and one of the most important tools to reduce childhood deaths caused by pathogens. The concept of vaccines is basically to take something safe, make it immunogenic and induce an immune response in the host that will protect it against something dangerous. Live attenuated
Matti Sällberg
wiley   +1 more source

ZBTB11 Promotes Breast Cancer Progression by Activating FBXO28‐Mediated MST1 Degradation and Suppressing Hippo Signaling

Advanced Science, Volume 13, Issue 56, 9 October 2026.
ZBTB11 is identified as an oncogenic transcription factor that activates FBXO28 in breast cancer. FBXO28 promotes K48‐linked ubiquitination and degradation of MST1, suppressing Hippo signaling and enhancing epithelial–mesenchymal transition and metastasis. This transcription‐to‐ubiquitination cascade defines a prognostic biomarker axis and highlights a
An Xu, Xiang‐Nan Xu, Xiao Huang, Zhou Luo, Chun‐Lian Li, Yang Du, Cheng Yan, Xiao‐Jie Yu, Jian‐Wen Wang, Long‐Di Yao, De‐Yuan Fu   +10 more
wiley   +1 more source

Taming Mre11–Rad50 at Telomeres: Convergent Strategies for Chromosome‐End Protection Across Evolution

BioEssays, Volume 48, Issue 10, October 2026.
All telomeres must be protected from DNA repair enzymes. This review explores how, from bacteriophages to mammals, unrelated telomere proteins have converged on the same recurring strategies: inhibiting the Mre11–Rad50 nuclease directly or physically shielding DNA ends. ABSTRACT Telomere biology is often framed as a uniquely eukaryotic problem, yet the
Florian Roisné‐Hamelin, Stephan Gruber   +1 more
wiley   +1 more source

Genome of Alaskapox Virus, a Novel Orthopoxvirus Isolated from Alaska

Viruses, 2019
Since the eradication of smallpox, there have been increases in poxvirus infections and the emergence of several novel poxviruses that can infect humans and domestic animals. In 2015, a novel poxvirus was isolated from a resident of Alaska.
Crystal M. Gigante, Jinxin Gao, Shiyuyun Tang, Andrea M. McCollum, Kimberly Wilkins, Mary G. Reynolds, Whitni Davidson, Joseph McLaughlin, Victoria A. Olson, Yu Li   +9 more
doaj   +1 more source

The Lord of the Rings: Cysteine bonds crosslink the tail of siphovirus

Protein Science, Volume 35, Issue 10, October 2026.
Abstract Long, non‐contractile tails composed of helical hexameric protein repeats that assemble into continuous tubular structures characterize siphoviruses. The siphovirus tail tube protein gp39 contains two cysteine residues per monomer. Cryo‐electron microscopy revealed that these cysteines are oriented toward the interface between the rings, which
Simona Povilonienė, Giedrius Sasnauskas, Giedrė Tamulaitienė, Greta Labutytė, Martynas Talaikis, Algirdas Mikšys, Aurelija Zajančkauskaitė, Lidija Truncaitė, Rolandas Meškys, Vida Časaitė   +9 more
wiley   +1 more source

Infections humaines à poxvirus

, 2019
Poxvirus (PXV) infections are a common cause of cutaneous signs. In France, certain forms of poxvirus are frequent and benign (molluscum contagiosum), while others are rare but potentially serious (cowpox virus [CPXV]).
Bohelay, G., Duong, T.-A.
core   +1 more source

A Review of Nonsteroidal Anti‐Inflammatory Drugs for Food‐Producing Animals With a Focus on Potential Applications for Farmed Finfish

Journal of Fish Diseases, Volume 49, Issue 10, October 2026.
ABSTRACT In finfish aquaculture, there are several inflammatory diseases impacting productivity and animal welfare, however there are limited options available to veterinarians to treat inflammation and pain in fish. Nonsteroidal anti‐inflammatory drugs (NSAIDs) are widely used in terrestrial animals raised for human consumption to treat a range of ...
Chloe J. English, Christine Huynh, William Roy, James W. Wynne, Hamish Rodger   +4 more
wiley   +1 more source