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In situ structure of the poxvirus portal complex
Poxviruses are a family of large, complex double-stranded DNA viruses that includes human pathogens such as variola—the cause of smallpox—and monkeypox. Recent outbreaks of mpox underscore the need for a better understanding of poxvirus biology
Thomas Calcraft +3 more
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BackgroundSome human poxvirus infections can be acquired through zoonotic transmission. We report a previously unknown poxvirus infection in 2 patients, 1 of whom was immunocompromised; both patients had known equine contact.MethodsThe patients were ...
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, 2017 dissertationViruses undergo rapid genetic changes in response to selective forces imposed by host immune defenses. All organisms are at risk of virus infections, and the ancient and ongoing coevolution between viruses and their hosts have shaped genome ...
Cone, Kelsey Rogers
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, 2014 Poxvirus-based vaccines have a long record of efficacy as both anti-tumour agents and vectors for gene therapy in different human tumour models. Interestingly, several studies of these vaccines have now entered the clinical evaluation phase for safety ...
MODESTI, ANDREA +14 more
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A Flagellin-Poxvirus Antigen Vaccine: Strengths and Limitations
, 2009 Bacterial flagellin is a potent adjuvant that enhances adaptive immune responses to a variety of antigens. The vaccinia virus antigens L1R and B5R are highly immunogenic in the context of the parent virus, but recombinant forms of the proteins are only ...
Delaney, Kristen
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, 1986 A case of poxvirus infection ill a flock of turkeys is reported. The affected turkeys had nodular wartlike growths of various sizes and shapes on the unfeathered skill of face, around the eyelids and on the feet.
Ideris, Aini, Ibrahim, A. Latif
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Poxvirus Use a "Gene Accordion" to Tune Out Host Defenses
, 2012 A multistep process of gene amplification, mutation, and reduction allows poxvirus to overcome host antiviral defenses.
Andersson, Dan I.,, Roth, John R.
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, 2010 Most DNA viruses selfishly exploit the cellular transcription machinery of infected cells. Poxviruses are unique among DNA viruses in that they encode the majority of the enzymes required for RNA synthesis.
Bruce A Knutson, Steven S Broyles
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Dermatoses of nipple as molluscum contagiosum – Clinical dilemma
Journal of Family Medicine and Primary Care, 2018 Molluscum contagiosum is a very common skin and mucosal disease of viral origin, caused by molluscum contagiosum virus (MCV) 0 of poxvirus family. With the eradication of smallpox, MCV is the only member of the poxvirus family that causes substantial ...
Puneet K Agarwal, Chirag S Dausage
doaj +1 more source
Poxvirus A51R: A microtubule maestro and virulence virtuoso [PDF]
Seo et al.1 shed light on virus-host interactions as they reveal how poxvirus A51R stabilizes microtubules in infected cells, which impacts vaccinia virus virulence in mice by potentially inhibiting reactive-oxygen-species-dependent antiviral responses ...
G.W. Gant Luxton +3 more
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