Results 81 to 90 of about 24,392 (225)
Bisbenzimide compounds inhibit the replication of prototype and pandemic potential poxviruses
We previously identified the bisbenzimide Hoechst 33342 (H42) as a potent multi-stage inhibitor of the prototypic poxvirus, the vaccinia virus (VACV), and several parapoxviruses.
Jerzy Samolej +8 more
doaj +1 more source
Genome of Alaskapox Virus, a Novel Orthopoxvirus Isolated from Alaska
Since the eradication of smallpox, there have been increases in poxvirus infections and the emergence of several novel poxviruses that can infect humans and domestic animals. In 2015, a novel poxvirus was isolated from a resident of Alaska.
Crystal M. Gigante +9 more
doaj +1 more source
Eczema Monkeypoxicum Following Sexual Transmission Treated With Tecovirimat
Capsule summary Mpox is a zoonotic infection that may present severe dissemination in patients with pre‐existing dermatoses. We report a 30‐year‐old man with active atopic dermatitis who developed extensive, sexually transmitted mpox with widespread cutaneous involvement consistent with eczema monkeypoxicum.
Andrés Vidal González +6 more
wiley +1 more source
Les vecteurs viraux : outils modernes de vaccination [PDF]
Les vaccins destinés aux animaux appartiennent à deux grandes catégories : les vaccins à agents vivants, et ceux à agents inertes. Depuis quelques années, dans chacune de ces catégories, les innovations technologiques ont considérablement amélioré et ...
Bertagnoli, Stéphane +6 more
core
Using purine skews to predict genes in AT-rich poxviruses [PDF]
BioMed CentralBackground: Clusters or runs of purines on the mRNA synonymous strand have been found in many different organisms including orthopoxviruses.
Da Silva, Melissa, Upton, Chris
core +1 more source
Poxviruses have evolved a wide array of mechanisms to evade the immune response, and we provide an overview of the different immunomodulatory strategies. Poxviruses prevent the recognition of viral DNA that triggers the immune responses and inhibit signaling pathways within the infected cell. A unique feature of poxviruses is the production of secreted
Hernáez, Bruno, Alcamí, Antonio
openaire +3 more sources
This review focuses on the clinical features, molecular mechanisms, treatment methods, and preventive measures of the VZV, with the aim of providing a theoretical basis for the development of new treatment and prevention methods for HZ. ABSTRACT Varicella zoster virus (VZV) is a ubiquitous human herpesvirus that establishes lifelong latency and causes ...
Lei Peng +8 more
wiley +1 more source
A novel candidate HIV vaccine vector based on the replication deficient Capripoxvirus, Lumpy skin disease virus (LSDV) [PDF]
Background The Capripoxvirus, Lumpy skin disease virus (LSDV) has a restricted host-range and is being investigated as a novel HIV-1 vaccine vector. LSDV does not complete its replication cycle in non-ruminant hosts. Methods The safety of LSDV was tested
Anna-Lise Williamson +6 more
core +2 more sources
ABSTRACT Background: Orf virus (ORFV), a zoonotic member of the genus Parapoxvirus, causes contagious ecthyma in sheep and goats and poses significant economic and public health concerns. Despite frequent outbreaks, molecular data on ORFV circulating in Tanzania remain scarce.
Charles Mayenga +4 more
wiley +1 more source

