Results 91 to 100 of about 14,853 (241)
Neomycin resistance as a dominant selectable marker for selection and isolation of vaccinia virus recombinants [PDF]
, 1985 The antibiotic G418 was shown to be an effective inhibitor of vaccinia virus replication when an appropriate concentration of it was added to cell monolayers 48 h before infection. Genetic engineering techniques were used in concert with DNA transfection
Franke, Christine A. +3 more
core
Breaking barriers: The cGAS‐STING pathway as a novel frontier in cancer immunotherapy
Cancer Communications, Volume 45, Issue 11, Page 1513-1546, November 2025.Abstract Since its discovery, the cyclic GMP‐AMP synthase (cGAS)‐stimulator of the interferon gene (STING) signaling pathway has been considered a pivotal component of innate immunity and a promising target for cancer immunotherapy. Beyond its canonical role in pathogen defense, accumulating evidence has demonstrated that the cGAS‐STING pathway ...
Yuheng Yan +5 more
wiley +1 more source
Ecography, Volume 2025, Issue 11, November 2025.Hawaii has experienced profound declines in native avifauna alongside the introduction of numerous bird species. While site‐specific population studies are common, landscape‐level analyses of avian population dynamics are rare, particularly in island ecosystems. To address this gap, we used a density surface model to create a spatio‐temporal projection
Trevor Bak +5 more
wiley +1 more source
FUNCTIONAL ANALYSIS OF VIRAL SCHLAFEN FROM CAMELPOX VIRUS
, 2009 This thesis concerns gene 176R from camelpox virus (CMLV) that encodes a protein known as viral schlafen (v-slfn). v-slfn has an N-terminal domain related to the p26 protein from baculovirus and a C-terminal domain related to mammalian schlafen ...
Goodbody, Rory Eric, Goodbody, Rory Eric
core +1 more source
Full Genome Sequence of the Western Reserve Strain of Vaccinia Virus Determined by Third-Generation Sequencing. [PDF]
, 2018 The vaccinia virus is a large, complex virus belonging to the Poxviridae family. Here, we report the complete, annotated genome sequence of the neurovirulent Western Reserve laboratory strain of this virus, which was sequenced on the Pacific Biosciences
Boldogkői, Zsolt +5 more
core +2 more sources
Changes in HIV‐1 Reservoir Dynamics After Mpox Infection
Journal of Medical Virology, Volume 97, Issue 11, November 2025.ABSTRACT In May 2022, a large outbreak of monkeypox virus (MPXV) occurred in several non‐endemic regions worldwide. Another outbreak in 2024 raised global concerns, particularly for immunocompromised individuals like people with HIV (PWH). Since the latent HIV‐1 reservoir remains a major barrier to a cure, we investigated how past mpox infection ...
Guiomar Casado‐Fernández +14 more
wiley +1 more source
A Unifying Scenario on the Origin and Evolution of Cellular and Viral Domains [PDF]
, 2009 The cellular theory on the nature of life has been one of the first major advancements in biology. Viruses, however, are the most abundant life forms, and their exclusion from mainstream biology and the Tree of Life (TOL) is a major paradox in biology ...
Claudiu I. Bandea
core +1 more source
Pixelated pathologies: Camera trapping as a tool for monitoring wildlife health
Journal of Applied Ecology, Volume 62, Issue 11, Page 2894-2913, November 2025.Given the increasing emergence of diseases, some with conservation and public health implications, improving and expanding wildlife health surveillance strategies is imperative. Camera trapping is particularly relevant for detecting new outbreaks, monitoring high‐risk zones and evaluating risk mitigation measures. Abstract Camera trapping has become an
Patricia Barroso, Pablo Palencia
wiley +1 more source
TNF Decoy Receptors Encoded by Poxviruses [PDF]
, 2021 Francisco Javier Alvarez-de Miranda +3 more
openalex +1 more source
PathogensSince smallpox vaccination was discontinued in 1980, there has been a resurgence of poxvirus infections, particularly the monkeypox virus. Without a global recommendation to use the smallpox vaccine, the population is not immune, posing a severe threat ...
Karolina Gregorczyk-Zboroch +12 more
doaj +1 more source