Results 21 to 30 of about 14,853 (241)
Retrospective study of poxviruses diagnosed in cattle from Goiás State, Brazil (2010-2018)
: A retrospective study of poxvirus infections diagnosed in cattle from Goiás state (GO), Brazil, from 2010 to 2018, was performed. All cases have been investigated by the GO Official Veterinary Service (Agrodefesa), from which technical forms and ...
Lorena F. Silva +6 more
doaj +1 more source
The extraordinary evolutionary history of the reticuloendotheliosis viruses [PDF]
The reticuloendotheliosis viruses (REVs) comprise several closely related amphotropic retroviruses isolated from birds. These viruses exhibit several highly unusual characteristics that have not so far been adequately explained, including their extremely
A Katzourakis +95 more
core +3 more sources
Poxviruses Utilize Multiple Strategies to Inhibit Apoptosis
Cells have multiple means to induce apoptosis in response to viral infection. Poxviruses must prevent activation of cellular apoptosis to ensure successful replication. These viruses devote a substantial portion of their genome to immune evasion. Many of
Daniel Brian Nichols +2 more
doaj +1 more source
Enhancing the Immunogenicity of Vaccinia Virus
The conventional live smallpox vaccine based on the vaccinia virus (VACV) cannot be widely used today because it is highly reactogenic. Therefore, there is a demand for designing VACV variants possessing enhanced immunogenicity, making it possible to ...
Sergei N. Shchelkunov +11 more
doaj +1 more source
Vaccinia protein C16 blocks innate immune sensing of DNA by binding the Ku complex [PDF]
VACV gene C16L encodes a 37-kDa protein that is highly conserved in orthopoxviruses and functions as an immunomodulator. Intranasal infection of mice with a virus lacking C16L (vΔC16) induced less weight loss, fewer signs of illness and increased ...
Peters, Nicholas Edward +1 more
core +1 more source
Una nueva alerta mundial en salud causada por la viruela del simio
Introducción: La viruela del simio es una zoonosis de etiología viral causada por virus de la viruela del simio. Es una enfermedad endémica en los países africanos.
Richar Jose Gomez de la Rosa +1 more
doaj +1 more source
Mass vaccination has played a critical role in the global eradication of smallpox. Various vaccinia virus (VACV) strains, whose origin has not been clearly documented in most cases, have been used as live vaccines in different countries.
Sergei N. Shchelkunov +11 more
doaj +1 more source
Poxviruses are large, complex DNA viruses that have played several seminal roles in medicine and biological science. Cowpox virus was introduced by Jenner as the first human vaccine in 1796; widespread vaccination with vaccinia virus led to the global eradication of smallpox in 1977, the only human disease to have been eradicated....
Jessica Clark, Dayna Diven
+4 more sources
Cidofovir Activity against Poxvirus Infections
Cidofovir [(S)-1-(3-hydroxy-2-phosphonylmethoxypropyl)cytosine, HPMPC] is an acyclic nucleoside analog approved since 1996 for clinical use in the treatment of cytomegalovirus (CMV) retinitis in AIDS patients.
Robert Snoeck, Graciela Andrei
doaj +1 more source
Monkeypox: A Little-Studied Biological Threat to Russia
Monkeypox is a natural focal zoonosis of rodents and monkeys living in the Congo Valley (clade CB) and West Africa (clade WA). The special interest in monkeypox is due to its pandemic spread, which began in May 2022.
M. V. Supotnitskiy
doaj +1 more source

