Human cytomegalovirus tegument proteins (pp65, pp71, pp150, pp28) [PDF]
Human cytomegalovirus (HCMV), a member of the Betaherpesvirinae sub-family of Herpesviridae family, is a widespread pathogen that infects a majority of the world's population by early adulthood.
Tomtishen III John
doaj +3 more sources
Effect of Cytomegalovirus Recombinant Phosphoprotein 150 (pp150) on Function and Maturation of Murine Dendritic Cells: an In-Vitro Study [PDF]
Background: Tegument protein pp150 of cytomegaloviruses (CMVs) plays a vital role in all stages of viral life cycle, representing the most important tegument protein candidate for HCMV treatment.
Yousef Nikmanesh +7 more
doaj +3 more sources
The smallest capsid protein mediates binding of the essential tegument protein pp150 to stabilize DNA-containing capsids in human cytomegalovirus. [PDF]
Human cytomegalovirus (HCMV) is a ubiquitous herpesvirus that causes birth defects in newborns and life-threatening complications in immunocompromised individuals. Among all human herpesviruses, HCMV contains a much larger dsDNA genome within a similarly-
Xinghong Dai +10 more
doaj +6 more sources
P706: RESISTANCE TO HYPOMETHYLATING AGENTS (HMA) IN HIGH-RISKMYELODYSPLASTIC SYNDROME (HR-MDS): THE ROLE OF THE ADENOSINEDEAMINASE ACTING ON RNA 1 (ADAR1) ENZYME [PDF]
HemaSphere, Volume 7, Issue S3, August 2023.
Dimitriou D +10 more
europepmc +2 more sources
Citrus Diseases Exotic to Florida: Witches' Broom Disease of Lime (WBDL)
This paper discusses Witches' Broom Disease of Lime (WBDL). This document is Fact Sheet PP-228, one of a series of the Plant Pathology Department, UF/IFAS Extension. Original publication date: April 2006.
Kuang Ren Chung +2 more
doaj +5 more sources
Synthetic lethal mutations in the cyclin A interface of human cytomegalovirus. [PDF]
Generally, the antagonism between host restriction factors and viral countermeasures decides on cellular permissiveness or resistance to virus infection.
Henry Weisbach +5 more
doaj +1 more source
Control of Cytoplasmic Maturation Events by Cytomegalovirus Tegument Protein pp150 [PDF]
ABSTRACT Cytomegalovirus replication depends upon a betaherpesvirus-conserved 150-kDa tegument phosphoprotein (pp150; encoded by UL32) that supports the final steps in virion maturation at cytoplasmic assembly compartments. Amino acid substitutions were introduced into conserved region 1 (CR1) and CR2 of pp150, affecting a region
Ritesh, Tandon, Edward S, Mocarski
openaire +2 more sources
Epigenetic quantification of immunosenescent CD8+ TEMRA cells in human blood
We studied old individuals over 65 years of age. We studied their CD4+ and CD8+ T cell subpopulations, quantified the CMV‐specific antibodies, inflammation‐associated proteins, and DNA methylation levels of selected CpGs. Based on our data we developed an epigenetic model to estimate CD8+ TEMRA cell levels in whole blood.
Ahto Salumets +11 more
wiley +1 more source
Human cytomegalovirus structural proteins: immune reaction against pp150 synthetic peptides [PDF]
In the present study, several peptides of the major structural antigen (pp150) of human cytomegalovirus (CMV) have been chemically synthesized and tested by a modified slot blotting procedure for their ability to bind CMV-specific immunoglobulin G (IgG) and IgM present in human sera. The sequences of the peptides were deduced on the basis of either (i)
M P, Landini +3 more
openaire +2 more sources
The association of cytomegalovirus and multiple sclerosis was assessed in a case–control study of presymptomatically collected samples. Cytomegalovirus seropositivity was found to reduce the risk of developing multiple sclerosis by 30%. Interactions between cytomegalovirus, Epstein–Barr virus and human herpesvirus 6A serostatus further impact the risk ...
Viktor Grut +20 more
wiley +1 more source

