Cytomegalovirus pUL96 Is Critical for the Stability of pp150-Associated Nucleocapsids [PDF]
ABSTRACT Maturation of human cytomegalovirus (HCMV) initiates with nucleocapsids that egress from the nucleus and associate with a juxtanuclear cytoplasmic assembly compartment, where virion envelopment and release are orchestrated. Betaherpesvirus conserved proteins pp150 (encoded by UL32) and pUL96 are critical for HCMV growth in cell ...
Ritesh, Tandon, Edward S, Mocarski
openaire +2 more sources
Evidence for a Causal Association Between Human Cytomegalovirus Infection and Chronic Back Pain: A One-Sample Mendelian Randomization Study. [PDF]
ABSTRACT Background Chronic back pain (CBP) is a major cause of disability globally. While its etiology is multifactorial, specific contributing genetic and environmental factors remain to be discovered. Paraspinal muscle fat has been shown in human and preclinical studies to be related to CBP. One potential risk factor is infection by cytomegalovirus (
Naeini MK +4 more
europepmc +2 more sources
Betaherpesvirus-Conserved Cytomegalovirus Tegument Protein ppUL32 (pp150) Controls Cytoplasmic Events during Virion Maturation [PDF]
ABSTRACT The UL32 gene of human cytomegalovirus (CMV) encodes a prominent betaherpesvirus-conserved virion tegument protein, called pp150 (basic phosphoprotein/ppUL32), that accumulates within a cytoplasmic inclusion adjacent to the nucleus at late times during infection.
David P, AuCoin +3 more
openaire +2 more sources
Human cytomegaloviruses expressing yellow fluorescent fusion proteins--characterization and use in antiviral screening. [PDF]
Recombinant viruses labelled with fluorescent proteins are useful tools in molecular virology with multiple applications (e.g., studies on intracellular trafficking, protein localization, or gene activity).
Sarah Straschewski +5 more
doaj +1 more source
Indonesian Cryptocurrencies Legislative Readiness: Lessons from the United States
Cryptocurrencies can facilitate cross-border global transfers easily and pseudonymously. It can be converted into fiat currencies, making it suitable for money laundering crimes.
Hanif Nur Widhiyanti +2 more
doaj +1 more source
Konsequenzen einer zellzyklusunabhängigen viralen Genexpression für den lytischen Infektionszyklus des humanen Zytomegalievirus [PDF]
Das humane Zytomegalievirus (HCMV) ist ein ubiquitäres Pathogen, das zur Gruppe der Herpesviren gehört. Bei Immunsupprimierten wie zum Beispiel AIDS-Patienten oder Organtransplantierten aber auch bei Neugeborenen kann die HCMV-Infektion schwere ...
Schablowsky, Christoph
core +1 more source
A CRISPR‐Cas9 tool to explore the genetics of Bacillus subtilis phages
Significance and Impact of the Study: This study presents a new CRISPR‐Cas9 vector specifically designed for the use with Bacillus phages. It is more efficient than existing systems, and in combination with the established vector‐specific construction of artificial CRISPR arrays, it will contribute to better exploitation and understanding of viral ...
K. Otte +6 more
wiley +1 more source
Dates of birth and seasonal changes in well-being among 4904 subjects completing the seasonal pattern assessment questionnaire [PDF]
Background: Abnormal distributions of birthdates, suggesting intrauterine aetiological factors, have been found in several psychiatric disorders, including one study of out-patients with Seasonal Affective Disorder (S.A.D.).
Cameron, Isobel M. +4 more
core +1 more source
Cytomegalovirus (CMV) and Epstein‐Barr virus (EBV) infections are widely distributed throughout the world. EBV is linked to various hematological and autoimmune disorders whereas CMV might play important role in the progression of chronic hematological diseases, such as hemoglobinopathies, lymphomas, myelomas, hemophilia, and aplastic and sickle cell ...
Jean de Melo Silva +4 more
wiley +1 more source
Summary: Background: An understanding of the correlation between maternal immunity and congenital cytomegalovirus (CMV) infection is critical for informing the design and evaluation of an effective maternal vaccine.
Yue Huang +20 more
doaj +1 more source

