ppAT drives glutamine-dependent purine biosynthesis and malignant progression in hepatocellular carcinoma [PDF]
BMC CancerBackground Hepatocellular carcinoma (HCC) is characterized by profound metabolic reprogramming, including altered nitrogen metabolism that supports tumor survival. phosphoribosyl pyrophosphate amidotransferase (ppAT) is the rate-limiting enzyme in purine
Junbin Zhou +7 more
exaly +3 more sources
PRINSIP KEHATI-HATIAN PEJABAT PEMBUAT AKTA TANAH DALAM PENGURUSAN PERALIHAN TANAH “LETTER C” [PDF]
Masalah-Masalah Hukum, 2017 Penulisan jurnal ini membahas mengenai salah satu permasalahan tentang Prinsip Kehati-Hatiaan Pejabat Pembuat Akta Tanah Dalam Pengurusan Peralihan Tanah “Letter C”.
Hendry Dwicahyo Wanda
doaj +4 more sources
Discovery of Inhibitors of 4′-Phosphopantetheine Adenylyltransferase (PPAT) To Validate PPAT as a Target for Antibacterial Therapy [PDF]
Antimicrobial Agents and Chemotherapy, 2013 ABSTRACT Inhibitors of 4′-phosphopantetheine adenylyltransferase (PPAT) were identified through high-throughput screening of the AstraZeneca compound library. One series, cycloalkyl pyrimidines, showed inhibition of PPAT isozymes from several species, with the most potent inhibition of enzymes from Gram-positive species.
Grant K Walkup, Ning Gao
exaly +3 more sources
Obesogenic Dysregulation of Human Periprostatic Adipose Tissue Promotes the Viability of Prostate Cells and Reduces Their Sensitivity to Docetaxel and Cabazitaxel [PDF]
Medical SciencesBackground: Periprostatic adipose tissue (PPAT) has been shown to play a significant role in prostate cancer (PCa) development and progression. This relationship is further exacerbated by obesity, as PPAT-secreted factors increase PCa aggressiveness and ...
Mariana Feijó +9 more
doaj +2 more sources
Akibat Hukum Akta Jual Beli Yang Dibatalkan Oleh Pengadilan Terhadap Pembeli Yang Beritikad Baik
Recital Review, 2022 This research examine the legal consequences of a sale and purchase deed canceled by the court on buyers who have good faith. This research purpose to analyze and criticize the PPAT responsibilitie of the land deed whose deed was canceled by the court as
Akbar Mastang, Muskibah Muskibah
doaj +3 more sources
Periprostatic adipose tissue-derived extracellular vesicles modulate prostate cancer cell behaviour in vitro according to tumour grade [PDF]
Molecular MedicineBackground Periprostatic adipose tissue (PPAT) actively interacts with prostate cancer (PCa) cells, partly through the release of extracellular vesicles (EVs).
Verónica Arreaza-Gil +12 more
doaj +2 more sources
Bentuk Surat Kuasa Membebankan Hak Tanggungan Setelah Dikeluarkannya Peraturan Kepala Badan Pertanahan Nasional Nomor 8 Tahun 2012 Tentang Ketentuan Pelaksana Peraturan Pemerintah Nomor 24 Tahun 1997 Tentang Pendaftaran Tanah [PDF]
, 2016 The Power of Attorney of the Encumbrance Rights (SKMHT) is a special power of attorney which includes the power to impose the provision of encumbrance by the encumbrance grantor to the recipient of the encumbrance or other person authorized to it.
Pratamikha, N. P. (Ni)
core +3 more sources
In vitro Condensation Assay of Fluorescent Protein-Fused PRPP Amidotransferase Purified from Budding Yeast Cells [PDF]
Bio-ProtocolDe novo synthesis of purine nucleotide is essential for the production of genetic materials and cellular chemical energy. PRPP amidotransferase (PPAT) is the rate-limiting enzyme in de novo purine synthesis, thereby playing a crucial regulatory role in ...
Masak Takaine
doaj +2 more sources
ANALISIS PENETAPAN FORMASI JABATAN PPAT DIKABUPATEN TANGGAMUS
Fiat Justisia, 2016 This study aims to determine the determination of position formations Land Deed Officer (PPAT) in Tanggamus and factors penghambat- his. Determination of position formations PPAT in Tanggamus yet by 3 (three) factors according Permeneg formulation ...
Fx Sumarja
doaj +3 more sources
A nomogram based on radiomic features from peri-prostatic adipose tissue for predicting bone metastasis in first-time diagnosed prostate cancer patients [PDF]
AdipocytePurpose To evaluate a radiomics-based nomogram using peri-prostatic adipose tissue (PPAT) features for predicting bone metastasis (BM) in newly diagnosed prostate cancer (PCa) patients.Methods A retrospective study of 151 PCa patients (October 2010 ...
Bohao Liu +9 more
doaj +2 more sources