Results 11 to 20 of about 23,774 (215)

Phase separation of the PRPP amidotransferase into dynamic condensates promotes de novo purine synthesis in yeast. [PDF]

open access: yesPLoS Biology
De novo purine synthesis (DPS) is up-regulated under conditions of high purine demand to ensure the production of genetic materials and chemical energy, thereby supporting cell proliferation.
Masak Takaine   +3 more
doaj   +2 more sources

Preoperative Multiparametric MRI-Based Tumour-Periprostatic Adipose Tissue Interface Characterisation for Extraprostatic Extension Prediction in Prostate Cancer. [PDF]

open access: yesCancer Med
ABSTRACT Objective To evaluate the independent predictive value of tumour–periprostatic adipose tissue (PPAT) interface features on preoperative multiparametric magnetic resonance imaging (mpMRI) for extraprostatic extension (EPE) in prostate cancer and to compare discrimination and clinical net benefit with a baseline clinical model.
Zhang S   +8 more
europepmc   +2 more sources

Bayesian Ordered Lattice Design for Phase I Clinical Trials. [PDF]

open access: yesStat Med
ABSTRACT We develop a new framework specifically for early Phase I clinical trials called Bayesian Ordered Lattice Design (BOLD). This study is motivated by two key factors. First, Phase I clinical trials typically involve relatively small sample sizes, which can make the use of prior information on dose‐limiting toxicity (DLT) rates highly significant.
Wang GM, Tatsuoka C.
europepmc   +2 more sources

Fungsi Ppat Dan Bpn Dalam Penerbitan Sertifikat Hak Tanggungan [PDF]

open access: yesLEX PRIVATUM, 2015
Tujuan dilakukannya penelitian ini adalah untuk mengetahui bagaimana fungsi PPAT dalam penerbitan sertifikat hak tanggungan dan bagaimana fungsi BPN dalam penerbitan sertifikat hak tanggungan serta bagaimana otensitas akta pemberian hak tanggungan ...
Kaligis, E. (Esterina)
core   +3 more sources

MRI-measured periprostatic adipose tissue volume as a prognostic predictor in prostate cancer patients undergoing laparoscopic radical prostatectomy

open access: yesAdipocyte, 2023
In this study, we evaluated the association between the PPAT volume and the prognosis of PCa patients after LRP. We retrospectively analysed data of 189 PCa patients who underwent LRP in Beijing Chaoyang Hospital.
Tianyu Xiong   +7 more
doaj   +1 more source

Asas Publisitas Perjanjian Perkawinan (Post Nuptial Agreement)

open access: yesJurnal Ilmu Kenotariatan, 2023
Marriage agreements after Constitutional Court Decision Number 69/PUU/XII/2015 have a different concept regarding marriage agreements. A prenuptial agreement expanded to a postnuptial agreement has several problems, namely regarding the publicity of the ...
W. Werdiningsih
doaj   +1 more source

Periprostatic Adipose Tissue Microenvironment: Metabolic and Hormonal Pathways During Prostate Cancer Progression

open access: yesFrontiers in Endocrinology, 2022
The periprostatic adipose tissue (PPAT) is a site of invasion of prostate cancer (PCa) and is part of the microenvironment. It was shown that PPAT secretes factors and fatty acids (FAs) that alter the microenvironment of the PCa.
Paula Alejandra Sacca   +2 more
doaj   +1 more source

The Role of Regional Honor Council in Maintaining the Honor of Notary Position

open access: yesJurnal Ilmu Kenotariatan, 2023
A profession that in carrying out its duties, functions and authorities requires an ethics, so does a Notary. So the code of ethics is used as a guideline for the behavior of members of the profession in acting and behaving.
Isro Vita Nugrahaningsih
doaj   +1 more source

Penunjukan Camat Sebagai Ppat Sementara Di Wilayah Kerja Yang Formasi PPAT Telah Terpenuhi

open access: yesNotarius, 2022
The Land Deed Official, every year continues to increase, and the role of the sub-district head as a temporary PPAT is needed because the PPAT formation is unfulfilled in the working area. While the number of PPATs in the East Java Region is quite a bit, however in several districts in East Java with a large number of PPAT there are also have Temporary
Rizki Fitria Sari, Nabitatus Sa’adah
openaire   +1 more source

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