Results 51 to 60 of about 350,201 (281)

dUTPase is essential in zebrafish development and possesses several single‐nucleotide variants with pronounced structural and functional consequences

FEBS Open Bio, EarlyView.
dUTPases are involved in balancing the appropriate nucleotide pools. We showed that dUTPase is essential for normal development in zebrafish. The different zebrafish genomes contain several single‐nucleotide variations (SNPs) of the dut gene. One of the dUTPase variants displayed drastically lower protein stability and catalytic efficiency as compared ...
Viktória Perey‐Simon, Angéla Békesi, Latifa Kazzazy, Jázmin Mihály, Máté Varga, Beáta G. Vértessy, Kinga Nyíri   +6 more
wiley   +1 more source

Prevalence and Safety of Prescribing PPIs with Clopidogrel in Palestine

Patient Preference and Adherence, 2023
Abdallah Damin Abukhalil, Tala Al Sheikh,* Sandra Muallem,* Ni’meh Al-Shami, Hani A Naseef Pharmacy Department, Faculty of Pharmacy, Nursing and Health Professions, Birzeit University, Birzeit, West Bank, Palestine*These authors contributed ...
Abukhalil AD, Al Sheikh T, Muallem S, Al-Shami N, Naseef HA   +4 more
doaj  

Comorbid patient with GERD and cardiovascular disease receiving antiplatelet therapy. The possibilities of choosing a proton pump inhibitor on a case study

Медицинский совет, 2019
The high prevalence of cardiovascular disease and its frequent pathogenetic relationship with various comorbid diseases and conditions lead to polypragmasia and the development of undesirable adverse reactions.
I. G. Pakhomova
doaj   +1 more source

Doing Science: How to optimise patient and public involvement in your research [PDF]

, 2015
This paper considers how best to achieve patient and public involvement in research and how to get the most out of it http://ow.ly ...
Bjerg, A, Hardavella, G, Jacinto, T, Powell, P, Saad, N   +4 more
core   +3 more sources

Laser‐Induced Graphene from Waste Almond Shells

Advanced Functional Materials, EarlyView.
Almond shells, an abundant agricultural by‐product, are repurposed to create a fully bioderived almond shell/chitosan composite (ASC) degradable in soil. ASC is converted into laser‐induced graphene (LIG) by laser scribing and proposed as a substrate for transient electronics.
Yulia Steksova, Anna Chiara Bressi, Marina Galliani, Attilio Marino, Gianni Ciofani, Eduardo Machado‐Charry, Hilda Gomez Bernal, Alessandra Francini, Luca Sebastiani, Francesco Greco   +9 more
wiley   +1 more source

Multilayer Soft Photonic Arrays Inspired by Cephalopod Skin for High‐Density, Independent, and Multimodal Actuation

Advanced Functional Materials, EarlyView.
A vertically stacked, DEA‐driven photonic array inspired by cephalopod skin, featuring highly crystalline colloidal crystal gels with vivid color, low FWHM and scalability is presented. The multilayer design removes lateral pixel interference, achieving near‐100% fill factor with fully independent RGB actuation.
Maga Kim, Imbo Kong, Do Yoon Kim, Jaeyoung Choi, Seong‐Yu Choi, Yun Hyeok Lee, Sihwan Lee, Byung Ik Park, Gimin Sung, In‐Suk Choi, Wook Sung Kim, Jeong‐Yun Sun   +11 more
wiley   +1 more source

3D Numerical Modelling of Turbulent Flow in a Channel Partially Filled with Different Blockage Ratios of Metal Foam [PDF]

Journal of Applied Fluid Mechanics
The aim of the present research work is to understand the intricacies of fluid flow through a rectangular channel that has been partially filled with a metal foam block of different blockage ratio (0.16-1), with a pore density (5–30 Pores Per Inch i.e ...
A. Narkhede, N. Gnanasekaran
doaj   +1 more source

Preliminary Study of a Ninj1‐Loaded Bimodal Ultrasound/NIR Fluorescence Targeted Molecular Probe for Diagnosing Early‐Stage Inflammation in Coronary Microvascular Dysfunction

Advanced Healthcare Materials, EarlyView.
Coronary microvascular dysfunction (CMD) targeting remains a challenge for precise diagnosis. This work presents a dual‐modal nanoprobe (T‐IR780‐NBs) that combines ultrasound contrast with near‐infrared fluorescence. This technology utilizes proteomics‐derived antibodies that specifically localize to inflamed and injured cardiac tissue, enabling ...
Xiaohui Xu, Lina Guan, Baihetiya Tayier, Chen Yuan, Shangke Chen, Qi Shi, Yuming Mu   +6 more
wiley   +1 more source

Macrophage-Related Genes Biomarkers in Left Ventricular Remodeling Induced by Heart Failure

Reviews in Cardiovascular Medicine, 2022
Background: Elevated left ventricular mass index contributes to morbidity and mortality induced by heart failure and M2 macrophages play a critical role in left ventricular remodeling.
Yue Zheng, Yuheng Lang, Zhenchang Qi, Bingcai Qi, Wenqing Gao, Xiaomin Hu, Tong Li   +6 more
doaj   +1 more source

Large-scale analysis of disease pathways in the human interactome

, 2017
Discovering disease pathways, which can be defined as sets of proteins associated with a given disease, is an important problem that has the potential to provide clinically actionable insights for disease diagnosis, prognosis, and treatment ...
Agrawal, Monica, Leskovec, Jure, Zitnik, Marinka   +2 more
core   +1 more source