Results 41 to 50 of about 3,214 (169)
NMR assignments of the FKBP-type PPIase domain of FKBP42 from Arabidopsis thaliana [PDF]
The Atfkbp42 gene is associated with reduced and disoriented growth of Arabidopsis thaliana. Resonance assignments are reported for the FKBP-type PPIase domain of AtFKBP42. Signal intensities reveal an additional structure element that is atypical for such FKBP domains.
Burgardt Noelia Inés +4 more
openaire +4 more sources
Clostridioides difficile is the main cause for nosocomial antibiotic associated diarrhea and has become a major burden for the health care systems of industrial countries.
Can Murat Ünal +11 more
doaj +1 more source
Unfolding Plant Defence: Endoplasmic Reticulum Stress Signalling at the Plant‐Pathogen Interface
ABSTRACT The endoplasmic reticulum (ER) stress response, a conserved proteostasis network, has emerged as a central hub that reprograms plant immunity during pathogen attack. This review synthesises how plants harness ER‐stress signalling to mount multilayered defences and how pathogens have evolved counterstrategies to subvert these pathways.
Zhe Meng +8 more
wiley +1 more source
Molecular docking analysis of juglone with parvulin-type PPiase PrsA from Staphylococcus aureus
Staphylococcus aureus is an opportunistic pathogen that causes variety of infections range from mild skin diseases to life-threatening sepsis. It is also notorious for acquiring resistance to numerous antibiotics. Parvulin-type peptidyl-prolyl cis-trans isomerase (PPiase) domain containing PrsA protein is considered as an essential folding factor for ...
Dipten, Laskar +2 more
openaire +2 more sources
Components of SurA required for outer membrane biogenesis in uropathogenic Escherichia coli.
BackgroundSurA is a periplasmic peptidyl-prolyl isomerase (PPIase) and chaperone of Escherichia coli and other Gram-negative bacteria. In contrast to other PPIases, SurA appears to have a distinct role in chaperoning newly synthesized porins destined for
Kristin M Watts, David A Hunstad
doaj +1 more source
Abnormal type I collagen post-translational modification and crosslinking in a cyclophilin B KO mouse model of recessive osteogenesis imperfecta. [PDF]
Cyclophilin B (CyPB), encoded by PPIB, is an ER-resident peptidyl-prolyl cis-trans isomerase (PPIase) that functions independently and as a component of the collagen prolyl 3-hydroxylation complex.
Wayne A Cabral +14 more
doaj +1 more source
Structure‐guided and biochemical analyses indicate that DNA primase of Leishmania donovani represents a potential therapeutic target, as repurposed compounds, particularly Pritelivir, demonstrate marked inhibitory effects accompanied by reduced parasite proliferation, replication, and altered cellular morphology in in vitro and cell‐based studies ...
Deep Bhowmik +3 more
wiley +1 more source
Brucella spp. are the etiological agent of animal and human brucellosis. We have reported previously that cyclophilins of Brucella (CypA and CypB) are upregulated within the intraphagosomal replicative niche and required for stress adaptation and host ...
Emanuel J. Muruaga +5 more
doaj +1 more source
The effector MrB1 induces cytotoxicity in plant cells through oxidative stress, membrane damage, protein folding collapse, and energy failure. These alterations compromise cellular integrity and result in necrosis. ABSTRACT Frosty pod rot (FPR) is an invasive disease responsible for severe yield losses of cacao trees.
Taís Araújo Santos +7 more
wiley +1 more source
Genomic and Transcriptomic Insights Into Salinity Tolerance in Dry Pea
ABSTRACT Salinity is a major crop production constraint in dry pea (Pisum sativum L.), making the development of salt‐tolerant varieties essential to improve crop productivity and land‐use efficiency. The genetic mechanisms of salt tolerance in dry pea are largely unknown, and research on salt‐tolerant genes is limited.
Shailesh Raj Acharya +11 more
wiley +1 more source

